Tobi E Nagel,Ivy J Mutai,Theodore Josephs et al.
Tobi E Nagel et al.
BigDNA: Primer Design Software for Overlap-Based Assembly of Phage Genomes and Larger DNAs [0.03%]
基于重叠的噬菌体基因组和较大DNA组装引物设计软件BigDNA
Ivan Vuong,Catherine M Mageeney,Kelly P Williams
Ivan Vuong
Background: Gibson assembly and assembly-in-yeast are strategies to create long synthetic DNAs from diverse fragments, for example, when engineering bacteriophage genomes. Design for these methods requires terminal sequen...
Martha Clokie,Thomas Sicheritz-Pontén
Martha Clokie
Purification of Functional Gene Transfer Agents Using Two-Step Preparative Monolithic Chromatography [0.03%]
利用两步 preparative monolithic 层析纯化功能基因转移载体
Evan Langille,Christina S Bottaro,Andrew S Lang
Evan Langille
Background: Gene transfer agents (GTAs) are phage-like particles that transfer cellular genomic DNA between cells. A hurdle faced in studying GTA function and interactions with cells is the difficulty in obtaining pure an...
vHULK, a New Tool for Bacteriophage Host Prediction Based on Annotated Genomic Features and Neural Networks [0.03%]
一种基于基因组注释特征和神经网络的新型噬菌体宿主预测工具vHULK
Deyvid Amgarten,Bruno Koshin Vázquez Iha,Carlos Morais Piroupo et al.
Deyvid Amgarten et al.
Background: The experimental determination of a bacteriophage host is a laborious procedure. Thus, there is a pressing need for reliable computational predictions of bacteriophage hosts. ...
Special Issue on Phage/Host Combat: Phage Strategies for Taking Over the Host and Host Strategies for Defenses [0.03%]
噬菌体与宿主战斗的特别专栏：噬菌体占领宿主和宿主防御策略的对策研究
Martha R J Clokie,Deborah M Hinton
Martha R J Clokie
Lotta-Riina Sundberg,Noora Rantanen,Gabriel Magno de Freitas Almeida
Lotta-Riina Sundberg
Pathogenic bacteria are attracted toward mucosa, as it is their way of entry into the body. However, we know surprisingly little about the phage-bacterium interactions in the mucosal environment. Here, we explored the effect of the mucosal ...
Martha R J Clokie,Thomas Sicheritz-Pontén
Martha R J Clokie
Aline Tabib-Salazar,Sivaramesh Wigneshweraraj
Aline Tabib-Salazar
Post-transcriptional regulation (PTR) determines the fate of RNA in the cell and represents an important control point in the flow of genetic information and thus underpins many, if not all, aspects of cell function. Host takeover by phages...