Tailoring Effective Phage Cocktails for Long-Term Lysis of Escherichia coli Based on Physiological Properties of Constituent Phages [0.03%]
基于组成噬菌体的生理特性针对埃希氏大肠杆菌定制有效的噬菌体制剂以实现长期裂解
Tomoyoshi Kaneko,Toshifumi Osaka,Satoshi Tsuneda
Tomoyoshi Kaneko
Background: Bacteriophage (phage) therapy has regained attention as an alternative to antimicrobial agents for eliminating bacteria; however, the emergence of phage-resistant bacteria during the therapy is a major concern...
Novel Escherichia coli-Infecting Bacteriophages Isolated from Uganda That Target Human Clinical Isolates [0.03%]
来自乌干达的新类大肠杆菌感染细菌噬菌体可靶向人类临床分离株
Janet Yakubu Nale,Benjamin Chan,Nnaemeka Emmanuel Nnadi et al.
Janet Yakubu Nale et al.
Background: The antimicrobial resistance catastrophe is a growing global health threat and predicted to be worse in developing countries. Phages for Global Health (PGH) is training scientists in these regions to isolate r...
Phage Therapy in the Management of Urinary Tract Infections: A Comprehensive Systematic Review [0.03%]
全面系统性回顾噬菌体治疗在泌尿系统感染管理中的应用
Amany M Al-Anany,Payton B Hooey,Jonathan D Cook et al.
Amany M Al-Anany et al.
Urinary tract infections (UTIs) are a problem worldwide, affecting almost half a billion people each year. Increasing antibiotic resistance and limited therapeutic options have led to the exploration of alternative therapies for UTIs, inclu...
A Summer of Phage Conferences Reflects the Burgeoning Interest in Phages [0.03%]
暑期噬菌体会议反映人们对噬菌体日益增长的兴趣
Martha R J Clokie,Thomas Sicheritz-Pontén
Martha R J Clokie
Isolation and Characterization of Phages That Bypass the Requirement for RNA-Mediated Antitermination [0.03%]
分离和表征绕过RNA介导的终止因子要求的噬菌体
Rodney A King,Millicent Babbs,Kimberly Baugh et al.
Rodney A King et al.
Introduction: The rpoCY75N mutation in the zinc-binding domain of the β' subunit of Escherichia coli RNA polymerase blocks the RNA-based mechanism of transcription antitermination utilized by bacteriophage HK022. ...
"Two Is Better Than One": The Multifactorial Nature of Phage-Antibiotic Combinatorial Treatments Against ESKAPE-Induced Infections [0.03%]
“1+1>2”——噬菌体与抗生素联合治疗对抗ESKAPE感染的协同效应机制研究
Gale Bernice N Fungo,John Christian W Uy,Kristiana Louise J Porciuncula et al.
Gale Bernice N Fungo et al.
Phage-antibiotic synergy (PAS) has been extensively explored over the past decade, with the aim of developing more effective treatments against multidrug-resistant organisms. However, it remains unclear how to effectively combine these two ...
In Vitro Evolution to Increase the Titers of Difficult Bacteriophages: RAMP-UP Protocol [0.03%]
体外进化以提高困难细菌噬菌体的滴度：RAMP-UP协议
Danielle N Kok,Joanne Turnbull,Nobuto Takeuchi et al.
Danielle N Kok et al.
Background: Bacteriophages are becoming increasingly important in the race to find alternatives to antibiotics. Unfortunately, bacteriophages that might otherwise be useful are sometimes discarded due to low titers making...
New Bacteriophages Members of the Ackermannviridae Family Specific for Klebsiella pneumoniae ST258 [0.03%]
新型肺炎克雷伯菌ST258的噬菌体成员_ACKERMANNVIRIDAE家族成员
Estefanía Tisalema-Guanopatín,Fausto Cabezas-Mera,Karla Nolivos-Rodríguez et al.
Estefanía Tisalema-Guanopatín et al.
Background: Carbapenem-resistant Klebsiella pneumoniae, particularly isolates classified as sequence-type 258 (ST258), are multidrug-resistant strains that are strongly associated with poor-prognosis nosocomial infections...
Characterization of a Diverse Collection of Salmonella Phages Isolated from Tennessee Wastewater [0.03%]
来自田纳西州废水的一系列沙门氏菌噬菌体的表征
Daniel W Bryan,Lauren K Hudson,Jia Wang et al.
Daniel W Bryan et al.
Background: Salmonella enterica is one of the most prevalent bacterial foodborne pathogens. Salmonella phages are currently used in biocontrol applications and have potential for use as therapeutics. ...