Caitlin M Carmody,Emma L Farquharson,Sam R Nugen
Caitlin M Carmody
Background: Increasing the quantity and detail of bacteriophage genomic data is critical to broadening our understanding of how bacteriophages operate to allow us to harness their unique properties for biotechnology advan...
Phage Annotation Guide: Guidelines for Assembly and High-Quality Annotation [0.03%]
噬菌体注释指南：组装和高质量注释的指导原则
Dann Turner,Evelien M Adriaenssens,Igor Tolstoy et al.
Dann Turner et al.
All sequencing projects of bacteriophages (phages) should seek to report an accurate and comprehensive annotation of their genomes. This article defines 14 questions for those new to phage genomics that should be addressed before submitting...
Solvent Extraction of Klebsiella pneumoniae Bacteriophage Lysates with 1-Dodecanol Results in Endotoxin Reduction with Low Risk of Solvent Contamination [0.03%]
使用1-十二醇萃取肺炎克雷伯氏菌噬菌体裂解液可减少内毒素并具有较低的溶剂污染风险
Jordyn Michalik-Provasek,Harley Parker,Lauren Lessor et al.
Jordyn Michalik-Provasek et al.
Antimicrobial resistance in pathogenic bacteria is increasing worldwide. One solution to this crisis is bacteriophage therapy, a treatment that harnesses naturally occurring bacterial viruses to invade and lyse antimicrobial resistant bacte...
Eleanor M Townsend,Lucy Kelly,Lucy Gannon et al.
Eleanor M Townsend et al.
Introduction: Klebsiella is a clinically important pathogen causing a variety of antimicrobial resistant infections in both community and nosocomial settings, particularly pneumonia, urinary tract infection, and sepsis. Bacteriophage (phage...
Bacteriophages as Biocontrol Agents for Flavobacterium psychrophilum Biofilms and Rainbow Trout Infections [0.03%]
用于大肠杆菌心理嗜磷菌生物膜和虹彩 trout 感染的噬菌体生物防治剂
Krister Sundell,Lotta Landor,Daniel Castillo et al.
Krister Sundell et al.
Background: Bacteriophages (phages) have been proposed as an alternative to antibiotics and surface disinfectants for treatment of Flavobacterium psychrophilum biofilms and fish infections in aquaculture settings. The aim of the study was t...
Catherine A Hernandez,Andrea J Salazar,Britt Koskella
Catherine A Hernandez
Background: One crucial first step in bacteriophage therapy is choosing a phage to apply, which involves screening for effectiveness in a meaningful way. Increasingly, research suggests that in vitro tests of phage-mediated bacterial lysis ...
Methods for Extraction and Detection of Pf Bacteriophage DNA from the Sputum of Patients with Cystic Fibrosis [0.03%]
囊性纤维化患者痰液Pf噬菌体DNA的提取及检测方法
Elizabeth B Burgener,Patrick R Secor,Michael C Tracy et al.
Elizabeth B Burgener et al.
Background: There is increasing interest in the pulmonary microbiome's bacterial and viral communities, particularly in the context of chronic airway infections in cystic fibrosis (CF). However, the isolation of microbial DNA from the sputu...
Tailored Antibacterials and Innovative Laboratories for Phage (Φ) Research: Personalized Infectious Disease Medicine for the Most Vulnerable At-Risk Patients [0.03%]
针对最脆弱高危患者的个性化感染病医学的量身定制抗菌素和创新型实验室噬菌体(Φ)研究
Austen L Terwilliger,Carmen Gu Liu,Sabrina I Green et al.
Austen L Terwilliger et al.
Mutation is the most powerful driver of change for life on Earth. Pathogenic bacteria utilize mutation as a means to survive strong live-die selective pressures generated by chemical antibiotics. As such, the traditional drug-making pipelin...