The group A Streptococcus interleukin-8 protease SpyCEP promotes bacterial intracellular survival by evasion of autophagy [0.03%]
链球菌分泌的SpyCEP蛋白酶通过逃避自噬促进细菌在细胞内的存活作用
René Bergmann,Giuseppe Gulotta,Federica Andreoni et al.
René Bergmann et al.
Autophagy serves an innate immune function in defending the host against invading bacteria, including group A Streptococcus (GAS). Autophagy is regulated by numerous host proteins, including the endogenous negative regulator calpain, a cyto...
Bicarbonate Effects on Antibacterial Immunity and Mucus Glycobiology in the Cystic Fibrosis Lung: A Review With Selected Experimental Observations [0.03%]
小苏打对囊性纤维化肺部抗菌免疫和黏液糖生物学的影响：带有选定实验观察的综述
Ruth Siew,Tzung-Lin Ou,Samira Dahesh et al.
Ruth Siew et al.
The primary defect in cystic fibrosis (CF) is abnormal chloride and bicarbonate transport in the cystic fibrosis transmembrane conductance regulator (CFTR) epithelial ion channel. The apical surface of the respiratory tract is lined by an a...