Immediate Postoperative Evolution of Cerebral Doppler and Saturation Parameters After Cardiopulmonary Bypass in Infants With Congenital Heart Disease: A Prospective Cohort Study [0.03%]
先天性心脏病婴儿体外循环术后即时脑多普勒及血氧饱和度参数的前瞻性队列研究
Marina Mir,Guillaume Maitre,Adrian Dancea et al.
Marina Mir et al.
Objectives: To describe temporal trends and instantaneous relationships between middle cerebral artery (MCA) cerebral blood flow velocity, cerebral oxygen saturation (Csat), cerebral fractional tissue oxygen extraction (c...
Observational Study
Critical care explorations. 2026 Feb 13;8(2):e1364. DOI:10.1097/CCE.0000000000001364 2026
Performance of Intracranial Pressure Waveform Morphological Features as Biomarkers of Intracranial Hypertension [0.03%]
脑内压波形形态特征作为颅内高压生物标志物的效能研究
Haoer Shi,Bethany Young,Andrea L C Schneider et al.
Haoer Shi et al.
Importance: Intracranial hypertension (IH) is a life-threatening condition requiring timely intervention. Morphology of the intracranial pressure (ICP) waveform, especially the ratio of the second to the first ICP wavefor...
Strategies for Safer Cefepime Use to Prevent Neurotoxicity Using the Electronic Health Record [0.03%]
利用电子健康记录预防神经毒性的cefepime用药安全策略
Sahar F Zafar,Hemi Park,Alyssa R Letourneau et al.
Sahar F Zafar et al.
Cefepime, a cornerstone antibiotic in critical care, is associated with underrecognized cefepime-induced neurotoxicity (CIN), particularly in patients 65 years old and older. The true incidence is unknown due to inconsistent monitoring and ...
Prediction of Adverse Events in Single Ventricle Physiology Infants Using Artificial Intelligence Tools [0.03%]
使用人工智能工具预测单心室生理婴儿的不良事件
Min Yu,Lucas Saenz Gaitan,Alejandro Lopez Magallon et al.
Min Yu et al.
Background: Adverse events (AEs) within the cardiac ICU (CICU) are associated with high mortality and comorbidity. Patients with single ventricle (SV) physiology are particularly vulnerable to experiencing such events bef...
rECMOmender: Reinforcement Learning for Decision Support in Venovenous Extracorporeal Membrane Oxygenation Management [0.03%]
基于强化学习的静脉到静脉体外膜氧合管理决策支持系统
Jiafeng Song,Sagar B Dave,Yu Yang et al.
Jiafeng Song et al.
Context: Management of ventilator and venovenous extracorporeal membrane oxygenation (ECMO) settings in critically ill adults requires individualized decisions to balance oxygenation, ventilation, and complication risks. ...
Successful Heat Stroke-Induced Pediatric Acute Liver Failure Treatment With N-Acetylcysteine Case Report [0.03%]
一例热射病诱发儿童急性肝衰竭成功使用N-乙酰半胱氨酸治疗的病例报告
Archana Anandakrishnan,Amanda OHalloran,Tamir Diamond
Archana Anandakrishnan
Background: Previously healthy children are at risk of developing exertional heat stroke when experiencing extreme heat. Pediatric clinicians in primary care, emergency department, and critical care settings should be ver...
Exploring the Relationship Between Neighborhood Disadvantage and ICU Delirium Characteristics [0.03%]
探究社区不利因素与ICU谵妄特征之间的关系
Rosalyn Chi,Anthony J Perkins,Sikandar H Khan et al.
Rosalyn Chi et al.
Importance: Delirium is a neuropsychiatric syndrome characterized by fluctuating disturbances in attention and awareness, associated with worse clinical outcomes and higher mortality. Previous research studies have noted ...
Association Between Positive End-Expiratory Pressure at Venovenous Extracorporeal Membrane Oxygenation Initiation and Liberation Outcomes in Acute Respiratory Distress Syndrome: A Multicenter Retrospective Study [0.03%]
呼气末正压与急性呼吸窘迫综合征患者体外膜肺氧合初始置管及撤机结局的相关性分析:多中心回顾性研究
Takashi Hongo,Yoshinori Kosaki,Tetsuya Yumoto et al.
Takashi Hongo et al.
Importance: The optimal level of positive end-expiratory pressure (PEEP) during venovenous extracorporeal membrane oxygenation (ECMO) for acute respiratory distress syndrome (ARDS) remains uncertain. ...
Multicenter Study
Critical care explorations. 2026 Feb 5;8(2):e1375. DOI:10.1097/CCE.0000000000001375 2026
Daniel Nigri,Meredith C Winter,Patrick A Ross et al.
Daniel Nigri et al.
Importance: Viral bronchiolitis is the leading cause of nonelective admission to the PICU. Guidelines recommend management that focuses on supportive care. Evidence suggests that inhaled epinephrine may reduce lower airwa...
Guideline-Concordant Sedative and Analgesia Use in Critically Ill Patients Receiving Sustained Neuromuscular Blockade [0.03%]
重症监护中使用神经肌肉阻滞剂的患者中的指南一致镇静和镇痛疗法的应用
Megan E Feeney,Ava E Canova,Anica C Law et al.
Megan E Feeney et al.
Objectives: Given significant harms of awake paralysis, guidelines recommend combination sedation and analgesia during neuromuscular blockade. In this study, we sought to describe guideline-concordant use of parenteral se...
Multicenter Study
Critical care explorations. 2026 Jan 26;8(2):e1370. DOI:10.1097/CCE.0000000000001370 2026