Relationship Between Phenotyping and Individualized Absolute Risk Differences in Sepsis: A Secondary Analysis of Two Approaches in Two Multicenter Trials [0.03%]
脓毒症表型与个体化绝对风险差异之间的关系：来自两个多中心试验的两种方法的二次分析
Victor B Talisa,Sachin P Yende,Derek C Angus et al.
Victor B Talisa et al.
Objectives: Sepsis trials likely include patients who vary in response to therapeutic interventions. The optimal approach to identify such differences in treatment response remains unclear. Estimating individualized absol...
Randomized Controlled Trial
Critical care explorations. 2025 Oct 13;7(10):e1332. DOI:10.1097/CCE.0000000000001332 2025
Physiological Signal Entropy in Pediatric Traumatic Brain Injury: Looking Beyond the Obvious: A STARSHIP Study [0.03%]
儿童创伤性脑损伤的生理信号熵：超越表面现象：一项STARSHIP研究
Stefan Yu Bögli,Claudia Ann Smith,Peter Hutchinson et al.
Stefan Yu Bögli et al.
Objectives: Multimodality monitoring based prognostication in pediatric traumatic brain injury (TBI) relies heavily on the evaluation of instantaneous and easily interpretable monitoring values. Entropy quantifies the lev...
Observational Study
Critical care explorations. 2025 Oct 13;7(10):e1333. DOI:10.1097/CCE.0000000000001333 2025
Augmenting Mortality Prediction in Critically Ill Adults With Medication Data and Machine Learning Models [0.03%]
基于药物数据和机器学习模型增强重症成人患者死亡率预测
Brian Murray,Tianyi Zhang,Zhetao Chen et al.
Brian Murray et al.
Background: Mortality prediction in ICU adults is only marginally improved when medication regimen complexity (MRC) data is incorporated into traditional regression models. Machine learning (ML) may improve this predictio...
Biomarkers of Microcirculatory Dysfunction in Sepsis: A Pilot Prospective Observational Study [0.03%]
一项前瞻性观察研究：脓毒症微循环障碍的生物标志物
August Longino,Katharine Martin,Stephen Bourland et al.
August Longino et al.
Context: To evaluate and compare sublingual microscopy (SLM) to urinary glycosaminoglycan (GAG) assays, dimethylmethylene blue (DMMB) assay, and liquid chromatography tandem mass spectrometry (LC-MS/MS) quantification of ...
Observational Study
Critical care explorations. 2025 Oct 9;7(10):e1324. DOI:10.1097/CCE.0000000000001324 2025
Aging and Host Responses to Severe Infection: Proteomic Analysis of a Prospective Multicenter Cohort From Uganda [0.03%]
乌干达前瞻性多中心队列的蛋白质组分析：老龄化与重度感染后的宿主反应
Gabriel Conte Cortez Martins,Julius J Lutwama,Nicholas Owor et al.
Gabriel Conte Cortez Martins et al.
Objective: Severe infectious diseases are a leading cause of morbidity and mortality worldwide, particularly in sub-Saharan Africa (SSA), where young and middle-aged adults are disproportionately affected. Although age-re...
Multicenter Study
Critical care explorations. 2025 Oct 7;7(10):e1330. DOI:10.1097/CCE.0000000000001330 2025
Supervised Machine Learning Models Predicting Postoperative Low Cardiac Output Syndrome In Neonates [0.03%]
预测新生儿术后低心排血量综合征的监督机器学习模型
Orkun Baloglu,Xiaofeng Wang,Bradley S Marino et al.
Orkun Baloglu et al.
Objective: To train and test supervised machine learning (ML) models to predict low cardiac output syndrome (LCOS) within the first 48 postoperative hours in neonates undergoing cardiothoracic surgery. ...
Observational Study
Critical care explorations. 2025 Oct 3;7(10):e1327. DOI:10.1097/CCE.0000000000001327 2025
Supervised Machine Learning Models Predicting Postoperative Low Cardiac Output Syndrome In Neonates [0.03%]
基于监督的机器学习模型预测新生儿术后低心排综合征
Orkun Baloglu,Xiaofeng Wang,Bradley S Marino et al.
Orkun Baloglu et al.
Objective: To train and test supervised machine learning (ML) models to predict low cardiac output syndrome (LCOS) within the first 48 postoperative hours in neonates undergoing cardiothoracic surgery. ...
Observational Study
Critical care explorations. 2025 Oct 3;7(10):e1327. DOI:10.1097/CCE.0000000000001327 2025
Cognitive Load in Pediatric Critical Care Medicine: Tsunamis and a Thousand Cuts [0.03%]
儿科重症监护医学中的认知负荷：海啸与千刀割腹
Daniel E Ehrmann,Sara N Gallant,Sunkyung Yu et al.
Daniel E Ehrmann et al.
Importance: Excessive cognitive load impairs task performance and contributes to burnout, but studies of cognitive load in pediatric critical care medicine (PCCM) settings are limited. ...
Understanding the Outcomes of Extracorporeal Membrane Oxygen Support in Patients With Sickle Cell Trait [0.03%]
血红蛋白S病患者接受体外膜氧合支持的结果分析
Kate M Willsey,Michael E Plazak,Leonid Belyayev et al.
Kate M Willsey et al.
The impact of common hemoglobinopathies, such as sickle cell trait (SCT), on outcomes in adults requiring extracorporeal membrane oxygenation (ECMO) remains understudied. Extracorporeal Life Support Organization registry data was analyzed t...
How High-Flow Nasal Cannula Is Impacted by Nasogastric/Esophageal Tube: A Bench Study [0.03%]
鼻胃管/食道管对高流量鼻导管的影响：试验台研究
Fernando Vieira,Annia Schreiber,Mayson L A Sousa et al.
Fernando Vieira et al.
High-flow nasal cannula (HFNC) is a common noninvasive respiratory therapy for respiratory failure, offering positive airway pressure and dead space clearance. In critically ill patients, additional nasal tubes for feeding or monitoring are...