Functional Pharmacobezoar and Bowel Ischemia Requiring Hemicolectomy Complicating Extended-Release Carbamazepine-Venlafaxine Overdose [0.03%]
长效卡马西平-文拉法辛中毒继发药块形成及肠缺血致乙状结肠切除术
Mirna Gerges,Abigail Greek,Sarah McMullen
Mirna Gerges
Background: Overdoses of extended-release (ER) medications can cause life-threatening toxicity from prolonged gastrointestinal drug retention due to pharmacobezoar formation. This may result in severe complications includ...
Determinants of ICU Admission Care Limitation in Patients Younger Than 65 Years: A Prospective, Observational, Multicenter Study [0.03%]
影响
Edgar Guillon,Maud Jonas,Guillaume Rieul et al.
Edgar Guillon et al.
Importance: Intensivists daily face ethics decisions regarding care limitation at admission (LA) or withholding life-sustaining therapy (WHLST) at admission, but no study focuses on patient younger than 65 years. ...
Observational Study
Critical care explorations. 2026 Apr 22;8(4):e1396. DOI:10.1097/CCE.0000000000001396 2026
Venovenous Extracorporeal Membrane Oxygenation After Cardiac Arrest Due to Refractory Anaphylaxis From Nut Ingestion [0.03%]
难治性坚果过敏引起的 refractory nut anaphylaxis导致的心脏骤停后的静脉转流体外膜氧合 venovenous extracorporeal membrane oxygenation治疗
Catherine Yip,Katherine Hickey,Joanne Hojsak et al.
Catherine Yip et al.
Background: Severe anaphylaxis can cause vasoplegia, decreased cardiac output, bronchoconstriction, and acute pulmonary edema, leading to cardiopulmonary arrest. In evaluating these patients for extracorporeal membrane ox...
Awake Flexible Scope Intubation in Critically Ill Patients With Physiologically Difficult Airways: A Prospective, Observational Case Series [0.03%]
清醒纤维支气管镜引导插管在生理上难以插管的重症患者中的应用：前瞻性观察性病例系列研究
Daenis C D Camiré,Tara S Ramaswamy,Lawrence F Chu et al.
Daenis C D Camiré et al.
Importance and objectives: Asleep tracheal intubation is a potentially dangerous intervention in critically ill patients. Patients at high-risk of severe hypoxemia or hemodynamic collapse have a "physiologically difficult...
Observational Study
Critical care explorations. 2026 Apr 6;8(4):e1394. DOI:10.1097/CCE.0000000000001394 2026
Physician Gestalt Compared With Artificial Intelligence Model to Predict Intubation in Critically Ill Patients [0.03%]
与人工智能模型相比，医师对危重患者插管的预测能力评估
Michael A Miller,Xiaolei Lu,Alex Pearce et al.
Michael A Miller et al.
Importance: Accurate prediction of intubation in critically ill patients could enable interventions that improve patient outcomes. However, the performance of intensive care physicians compared with machine learning (ML) ...
Observational Study
Critical care explorations. 2026 Apr 2;8(4):e1393. DOI:10.1097/CCE.0000000000001393 2026
Is There Any Dose of Benzodiazepines Safe for Delirium in the PICU? A Secondary Analysis of the PICU Up! Pilot Trial Dataset [0.03%]
苯二氮卓类药物治疗PICU delirium有安全剂量吗？PICU Up! 候试验数据的次级分析结果
Isabella Blackman,Rachel De Armas,Sofia Padilla et al.
Isabella Blackman et al.
Importance: A better understanding of the relationship between sedative dose and PICU delirium is crucial for delirium prevention. Objectives: ...
Randomized Controlled Trial
Critical care explorations. 2026 Mar 31;8(4):e1389. DOI:10.1097/CCE.0000000000001389 2026
Ceragenin-Coated Endotracheal Tubes for the Reduction of Ventilator-Associated Pneumonia: A Prospective, Longitudinal, Crossover, Interrupted Time, Implementation Study (CEASE VAP Study) [0.03%]
减少呼吸机相关性肺炎的万应菌体涂层气管插管：前瞻性、纵向、交叉、中断时间实施研究（CEASE VAP 研究）
John Muscedere,Patrick A Norman,Christine D&#x;Arsigney et al.
John Muscedere et al.
Objective: To evaluate the impact of Ceragenin-coated endotracheal tubes (CSA ETTs) on the incidence of ventilator-associated pneumonia (VAP) in critically ill adults and assess feasibility of conducting a multicenter stu...
Multicenter Study
Critical care explorations. 2026 Mar 20;8(4):e1382. DOI:10.1097/CCE.0000000000001382 2026
Feasibility of a Large Language Model Chatbot to Support Parental Understanding in the PICU [0.03%]
大型语言模型聊天机器人在PICU支持家长理解的可行性研究
R Brandon Hunter,Satid Thammasitboon,Sreya Rahman et al.
R Brandon Hunter et al.
Objectives: To evaluate the feasibility of a large language model (LLM)-based chatbot for answering parental questions in the PICU and inform design of a randomized controlled trial (RCT). ...
Tocilizumab Efficacy Across Inflammatory Subphenotypes in COVID-19-Related Acute Respiratory Distress Syndrome [0.03%]
托珠单抗在COVID-19相关性急性呼吸窘迫综合征不同炎症亚表型中的疗效
Daan F L Filippini,Jessica Khyali,Malou Janssen et al.
Daan F L Filippini et al.
Objectives: This study evaluated whether the established efficacy of tocilizumab, an interleukin-6 (IL-6) receptor antagonist, differs between the hypoinflammatory and hyperinflammatory subphenotypes. ...
Post-Acute Sequelae of COVID-19 Persist Over 3 Years in Acute Lung Injury/Acute Respiratory Distress Syndrome Survivors But Are Not Associated With Persistent Thromboinflammation or Endothelial Dysfunction [0.03%]
急性肺损伤/急性呼吸窘迫综合征幸存者的新冠肺炎后遗症在三年内持续存在，但与持续的血栓炎症或内皮功能障碍无关
Ansley E Jones,Zain Khan,Claire F McGroder et al.
Ansley E Jones et al.
Importance: Inflammation, endothelial dysfunction, and complement activation are associated with COVID-19 acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). ...