Rapid Microbiological Diagnostics for Sepsis: Narrative Review of Current and Prospective Approaches [0.03%]
脓毒症的快速微生物学诊断：当前和未来方法叙述性回顾
Luke B Harrison,Zahra N Sohani,David Lasry et al.
Luke B Harrison et al.
Objectives: In this review, we aim to provide critical care clinicians with a concise introduction to the current and prospective tools that exist for rapid diagnostics in sepsis employed in the microbiology laboratory. O...
Christina Maratta,Melany Gaetani,Nicole K McKinnon et al.
Christina Maratta et al.
Importance: Pediatric cerebral venous sinus thrombosis (CVST) is being increasingly recognized and can pose substantial risks of morbidity and mortality. Data on the epidemiology, management, and outcomes of CVST in the P...
Observational Study
Critical care explorations. 2026 May 25;8(6):e1418. DOI:10.1097/CCE.0000000000001418 2026
PPARγ Variant rs10865710 and Mortality in Pediatric Septic Shock Stratified by Corticosteroid Exposure [0.03%]
糖皮质激素治疗与儿重感染性休克中PPARγ基因多态位点rs10865710型与死亡率之间的关系研究
Valentina Bonnefil,Stephen Standage,Andrew J Lautz et al.
Valentina Bonnefil et al.
Objectives: To determine whether genetic variation in peroxisome proliferator-activated receptor gamma (PPARγ) is associated with mortality across corticosteroid exposure strata in pediatric septic shock. ...
Observational Study
Critical care explorations. 2026 May 25;8(6):e1410. DOI:10.1097/CCE.0000000000001410 2026
External Validation, Recalibration, and Extension of a Prediction Model of Early Acute Kidney Injury in Critically Ill Children Using Multicenter Data [0.03%]
利用多中心数据对外科术后儿童急性肾损伤预测模型进行外部验证、再评价及扩展研究
Adam C Dziorny,Stephen Drury,Alex Clark et al.
Adam C Dziorny et al.
Background: Acute kidney injury (AKI) is common in critically ill children and is associated with high morbidity and mortality. Risk prediction models designed for clinical decision support implementation can facilitate e...
Multicenter Study
Critical care explorations. 2026 May 25;8(6):e1425. DOI:10.1097/CCE.0000000000001425 2026
Performance of the Ventilatory Ratio to Predict Intubation in Patients With COVID-19 Acute Respiratory Distress Syndrome [0.03%]
通气比预测COVID-19急性呼吸窘迫综合征患者插管的效能
Antoine Goury,Zoubir Djerada,Guillaume Thery et al.
Antoine Goury et al.
Objectives: Ventilatory ratio (VR) could be a useful marker of COVID-19 acute respiratory distress syndrome (ARDS) worsening, since its value has been shown to correlate with dead space and severity of non-COVID-19 ARDS. ...
Multicenter Study
Critical care explorations. 2026 May 25;8(6):e1423. DOI:10.1097/CCE.0000000000001423 2026
Beyond Net Ultrafiltration Rate: A Precision Fluid Management Paradigm Integrating Three Key Parameters for Pediatric Continuous Renal Replacement Therapy [0.03%]
超越超滤系数：一种整合三个关键参数的儿童连续性肾脏替代治疗精准液体管理理念
Wenjun Liu,Chunxiao Wang,Changyang Ye et al.
Wenjun Liu et al.
Importance: Fluid management in critically ill children receiving continuous renal replacement therapy (CRRT) is challenging due to limitations of conventional metrics. Net ultrafiltration rate (NUFR, mL/kg/hr) lacks pedi...
Substance Use and Delirium Trends in the Critically Ill During the Peri-COVID Period [0.03%]
围COVID时期危重症患者谵妄和物质使用趋势
Emma Bick,Benjamin J Sines,C Adrian Austin
Emma Bick
Importance: Substance use complicates many hospitalizations by increasing delirium rates, acuity, and costs. Its prevalence rose during the COVID-19 pandemic, potentially contributing to increased delirium in hospitalized...
Supporting Informed Surrogate Decision-Making in Deceased Donor Intervention Research: Co-Creating Educational Materials With Families [0.03%]
与家属共创教育资料支持知情代理决策在器官捐献干预研究中的应用
Nicholas Murphy,Charles Weijer,Janice Beitel et al.
Nicholas Murphy et al.
Deceased donor intervention research aims to improve organ donation and transplantation outcomes, but its feasibility often depends on obtaining valid informed consent from surrogate decision makers during a difficult time for families in t...
Extracorporeal Membrane Oxygenation for Pneumocystis Pneumonia: Outcomes in Patients From the Extracorporeal Life Support Organization [0.03%]
体外膜氧合治疗肺炎链球菌肺炎：来自体外生命支持组织患者的结局指标
Kyle J Henry,Emily R Thompson,Kealy Ham et al.
Kyle J Henry et al.
Objectives: Pneumocystis jirovecii pneumonia (PCP) can cause severe hypoxemic respiratory failure in immunocompromised patients. Contemporary outcomes of venovenous extracorporeal membrane oxygenation (VV ECMO) support fo...
Extracorporeal Membrane Oxygenation Combined With Esophageal Pressure-Guided Mechanical Ventilation as Salvage Therapies in Postpneumonectomy Acute Respiratory Distress Syndrome [0.03%]
体外膜氧合联合食道压引导机械通气在术后急性呼吸窘迫综合征患者中的应用研究
Emmanuelle Guérin,Jade Roland,India Sourieau et al.
Emmanuelle Guérin et al.
Background: Massive hemoptysis and postpneumonectomy acute respiratory distress syndrome (ARDS) are rare but life-threatening conditions with limited therapeutic options. This case highlights the feasibility of combining ...