Kirstin J Kooda,Julia Nelson,Sara E Ausman et al.
Kirstin J Kooda et al.
This study aimed to determine if extended infusion (EI; over > 3 hr) beta-lactam therapy increased IV access requirements compared with traditional dosing (TD; over 30 min). Eighty-six adult ICU patients treated with TD anti-pseudomonal bet...
Outcomes of Venovenous Extracorporeal Membrane Oxygenation for Pneumocystis jirovecii Pneumonia: A Multicenter Retrospective Case Series [0.03%]
静脉至静脉体外膜肺支持治疗新型隐球菌肺炎的预后：多中心病例系列回顾研究
Aaron M Pulsipher,Kyle Henry,Holenarasipur R Vikram et al.
Aaron M Pulsipher et al.
Pneumocystis jirovecii pneumonia (PCP) is a life-threatening opportunistic infection increasingly recognized among non-HIV immunocompromised patients. In severe cases progressing to acute respiratory distress syndrome, venovenous extracorpo...
Multicenter Study
Critical care explorations. 2025 Aug 4;7(8):e1296. DOI:10.1097/CCE.0000000000001296 2025
Characteristics and Outcomes of Patients Receiving Volatile Anesthetics in Near-Fatal Asthma: A Retrospective Observational Cohort Study [0.03%]
重度哮喘急性发作患者吸入麻醉药的临床特征及预后分析：回顾性队列研究
Christopher Remmington,Luigi Camporota,Daniel Taylor et al.
Christopher Remmington et al.
Importance and objectives: Inhaled volatile anesthetics are employed as rescue therapy in near-fatal asthma, despite limited evidence. This study aims to describe the characteristics, management, and outcomes of mechanica...
Observational Study
Critical care explorations. 2025 Jul 30;7(8):e1295. DOI:10.1097/CCE.0000000000001295 2025
Comparative Evaluation of Lipopolysaccharide Administration Methods to Induce Acute Lung Injury in Murine Models: Efficacy, Consistency, and Technical Considerations [0.03%]
小鼠急性肺损伤模型内毒素诱导方法的比较评估：效应、再现性及技术考量
Eva Kuhar,Duncan J Stewart,Doreen Engelberts et al.
Eva Kuhar et al.
Context: Direct preclinical lipopolysaccharide acute lung injury (ALI) models are commonly used to study acute respiratory distress syndrome. Differences in lipopolysaccharide delivery methods may impact lung injury sever...
Comparative Study
Critical care explorations. 2025 Jul 28;7(8):e1292. DOI:10.1097/CCE.0000000000001292 2025
Health Economic Evaluations in Intensive Care: An Updated Systematic Review [0.03%]
重症监护中的卫生经济学评估：系统回顾更新版
Christina-Le Nguyen,Wai Chung Tse,Thomas M Carney et al.
Christina-Le Nguyen et al.
Objectives: Intensive care is a critical but resource-intensive component of healthcare. Health economic evaluations, such as cost-effectiveness analyses (CEAs), offer valuable insights for decision-making by weighing the...
Epidemiology of Community-Acquired Versus Hospital-Acquired Sepsis in Acute Hospitals in Ireland, 2016-2022 [0.03%]
2016-2022年爱尔兰急性医院内获得性与社区获得性脓毒症的流行病学
Emer M Liddy,Doaa K Amin,Declan J McKeown et al.
Emer M Liddy et al.
Importance: Sepsis is a leading cause of morbidity and mortality. Understanding sepsis epidemiology is crucial to enable clinicians to identify patients at highest risk of developing and dying from sepsis. ...
Comparative Study
Critical care explorations. 2025 Jul 15;7(7):e1289. DOI:10.1097/CCE.0000000000001289 2025
Right Ventricular Longitudinal Strain Predicts Weaning Success in Cardiogenic Shock Patients Supported by a Microaxial Flow Pump [0.03%]
右心纵向应变可预测接受微型轴流泵支持的 cardiogenic 患者的脱机成功率Shock患者
Konstantinos Rapis,Francesco Paolo Lo Muzio,Alessandro Faragli et al.
Konstantinos Rapis et al.
Importance: The effect of left ventricular (LV) mechanical unloading on right ventricular (RV) function in patients with cardiogenic shock (CS) remains poorly understood, yet may have significant implications for device w...
Evaluation of Hydrocortisone Discontinuation Strategies in Septic Shock: A Retrospective Cohort Study [0.03%]
早期停用氢化可的松在脓毒性休克中效果的回顾性队列研究
Hanine O AlMubayedh,Rayd A AlMehizia,Abdul Salam et al.
Hanine O AlMubayedh et al.
Importance: While corticosteroid administration in septic shock has been shown to reduce vasopressor requirements and accelerate shock reversal, the optimal discontinuation strategy remains unexplored. ...
Association of Dynamic Arterial Elastance With Fluid Responsiveness in Critically Ill Children [0.03%]
动脉弹性与重症儿童液体反应性的相关性分析
Sarah B Walker,Kyle S Honegger,Michael S Carroll et al.
Sarah B Walker et al.
Objectives: Cardiac mechanical efficiency has been shown to be a predictor of fluid responsiveness (FR) in adults. Our goal was to assess the association between mechanical efficiency as measured by dynamic arterial elast...
Observational Study
Critical care explorations. 2025 Jul 14;7(7):e1291. DOI:10.1097/CCE.0000000000001291 2025
Troubleshooting Severe Airflow Obstruction With a Pressure-Limited Transport Ventilator: Lessons From Two Cases [0.03%]
有关使用限压转运呼吸机治疗重度气流受限的思考：两个病例的启示
Peter M Reardon,Melody J Bishop,Christopher J Yarnell et al.
Peter M Reardon et al.
Presentations of status asthmaticus or severe chronic obstructive pulmonary disease exacerbation can present a formidable challenge to effective invasive ventilation. The optimal ventilation strategy targets low respiratory rates and high i...