Monocyte Anisocytosis Can Discriminate Between Sepsis and Sterile Inflammation, but not Mortality, in Critically Ill Surgical/Trauma Patients: A Secondary Prospective Analysis [0.03%]
单核细胞不等大可以区分重症外科/创伤患者的脓毒症和无菌性炎症，但与死亡率无关：二次前瞻性分析
Miguel Hernández-Ríos,Ruoxuan Wu,Valerie A Polcz et al.
Miguel Hernández-Ríos et al.
Objectives background: Monocyte anisocytosis (monocyte distribution width [MDW]) has been previously validated to predict sepsis and outcome in patients presenting in the emergency department and mixed-population ICUs. De...
Observational Study
Critical care explorations. 2025 Sep 9;7(9):e1309. DOI:10.1097/CCE.0000000000001309 2025
Family-Partnered Delirium Care in the ICU: Feasible Today, Essential Tomorrow? [0.03%]
重症监护病房中的家庭参与性德尔格照护：今日具有可行性，明日则必不可少？
Vanessa Vater,Peter Nydahl,Pam Ramsay
Vanessa Vater
Immune Response Subphenotyping to Predict Mortality in Sepsis: A Prospective Study in Resource-Limited Setting [0.03%]
免疫应答亚型表型预测脓毒症患者的病死率：资源匮乏地区的前瞻性研究
Velma Herwanto,Robert Sinto,Leonard Nainggolan et al.
Velma Herwanto et al.
Importance: Sepsis remains a leading cause of death in infectious cases. The heterogeneity of immune responses is a major challenge in the management and prognostication of patients with sepsis. Identifying distinct immun...
Acute Respiratory Distress Syndrome Phenotypes After Stem Cell Transplantation: A Latent Class Analysis [0.03%]
造血干细胞移植后急性肺损伤的亚型:潜在类别分析
Svetlana Herasevich,Kiyan Heybati,William J Hogan et al.
Svetlana Herasevich et al.
Objective: To identify distinct phenotypes of acute respiratory distress syndrome (ARDS) developing after hematopoietic cell transplantation (HCT), using routinely available clinical data at ICU admission. ...
Multicenter Study
Critical care explorations. 2025 Sep 5;7(9):e1312. DOI:10.1097/CCE.0000000000001312 2025
Hemodynamic Effects of Guideline-Based Sedation in Mechanically Ventilated Adults: A Multicenter Observational Analysis [0.03%]
基于指南的镇静对机械通气成人患者血流动力学影响的多中心观察分析
Kiyan Heybati,Guozhen Xie,Jiawen Deng et al.
Kiyan Heybati et al.
Importance: Propofol is a first-line sedative for adults receiving invasive mechanical ventilation (IMV). However, it can contribute to hemodynamic instability, especially during intubation. The magnitude, timing, risk fa...
Observational Study
Critical care explorations. 2025 Sep 5;7(9):e1313. DOI:10.1097/CCE.0000000000001313 2025
Mean Airway Pressure-An Informative but Overlooked Indicator of Mechanical Power [0.03%]
平均气道压——一个被忽视的机械通气做功的衡量指标
Michael G Michalik,Philip S Crooke,John J Marini
Michael G Michalik
Mean airway pressure, a monitored variable continuously available on the modern ventilator, is the pressure measured at the airway opening averaged over the time needed to complete the entire respiratory cycle. Mean airway pressure is well ...
Progesterone for Traumatic Brain Injury, Experimental Clinical Treatment III Trial Revisited: Objective Classification of Traumatic Brain Injury With Brain Imaging Segmentation and Biomarker Levels [0.03%]
孕酮治疗创伤性脑损伤的实验性临床III期试验重新评估：基于脑影像分割和生物标志物水平的客观分类创伤性脑损伤
Scarlett Cheong,Rishabh Gupta,Sharada Kadaba Sridhar et al.
Scarlett Cheong et al.
Objective: This post hoc study of the Progesterone for Traumatic Brain Injury, Experimental Clinical Treatment (ProTECT) III trial investigates whether improving traumatic brain injury (TBI) classification, using serum bi...
Randomized Controlled Trial
Critical care explorations. 2025 Sep 5;7(9):e1306. DOI:10.1097/CCE.0000000000001306 2025
Organ Failure, Endotoxin Activity, and Mortality in Septic Shock [0.03%]
脓毒症休克患者器官功能衰竭与内毒素活性变化及其对病死率的影响
Luca Molinari,Mark A Tidswell,Ali Al-Khafaji et al.
Luca Molinari et al.
Importance: The relationship between endotoxin activity, organ failure, and mortality is not well understood. Objective: To test whethe...
Observational Study
Critical care explorations. 2025 Aug 28;7(9):e1308. DOI:10.1097/CCE.0000000000001308 2025
Inter-rater Agreement of Richmond Agitation Sedation Scale Assessments in Adult Patients Receiving Mechanical Ventilation in the ICU: A Cross-Sectional Study [0.03%]
RICU机械通气成人患者RASS评分的计分者间可靠度调查研究
Mikita Fuchita,Jack Pattee,David Le et al.
Mikita Fuchita et al.
Importance: Accurate and reliable sedation assessment is crucial to improving patient outcomes in the ICU. Objective: To evaluate the i...
Prior Use of Renin-Angiotensin System Inhibitors and Risk of Renal Replacement Therapy in Critically Ill Elderly Patients With Sepsis: A Population-Based Cohort Study [0.03%]
脓毒症重症老年患者肾素-血管紧张素系统抑制剂的使用对其肾脏替代治疗风险的影响：基于人群的队列研究
Victoria Otero Castro,Damon C Scales,Federico Angriman
Victoria Otero Castro
Objectives: We sought to estimate the association between chronic use of renin-angiotensin system inhibitors and acute kidney injury requiring renal replacement therapy in critically ill adult patients with sepsis. ...