Two Physiologic Latent Classes of Acute Hypoxemic Respiratory Failure in Sepsis Are Distinguished by Lung Mechanics and Gas Exchange [0.03%]
感染性休克中由肺力学和气体交换区分的急性缺氧性呼吸衰竭两种生理隐匿类型
Rachel M Bennett,Kaitlyn C Housel,Tiffanie K Jones et al.
Rachel M Bennett et al.
Objectives: Physiologic subtypes of acute hypoxemic respiratory failure (AHRF) may confer a differential response to treatments, particularly therapeutic strategies that are specific to pulmonary organ failure. We sought ...
Predictors of Anemia Intolerance for Real-Time Transfusion Decision-Making During Resuscitation of Trauma Subjects: A Machine Learning Approach Using Heart Rate Variability [0.03%]
基于心率变异性运用机器学习方法预测创伤患者复苏过程中实时输血决策的贫血耐受指标
Mathangi Gopalakrishnan,Jie Chen,Rahul Goyal et al.
Mathangi Gopalakrishnan et al.
Objectives: RBC transfusion in anemic patients with sustainable tolerance may cause harm, emphasizing the need for reliable metrics that quantify adequacy (oxygen delivery ≥ demand) and sustainability (oxygen delivery re...
Evaluating the Safety of Current Intraosseous Needles and the Potential for Age-Based Guidance Using a Large-Scale Pediatric CT/MRI Imaging Study [0.03%]
基于年龄的骨内针安全性的影像学研究指导的潜力评估项目
Dilshan Rajan,Anuk Dias,Shaliny Jadhav et al.
Dilshan Rajan et al.
Objectives: To use 3D imaging modalities to obtain precise measurements of the proximal tibia in pediatric patients and assess the safety of current intraosseous needle lengths (15 and 25 mm). ...
Comparative Effectiveness of Less vs. More Frequent Hydrocortisone Dosing in Septic Shock [0.03%]
不同频率氢化可的松剂量在休克中的疗效比较研究
Alan Hao,Tianshi David Wu,Keegan Collins et al.
Alan Hao et al.
Objectives: Guidelines recommend hydrocortisone as an adjunctive treatment in septic shock, but the optimal dosing regimen is unknown. A national shortage of hydrocortisone in 2023 prompted a change in institutional pract...
Comparative Study
Critical care explorations. 2025 Sep 15;7(9):e1316. DOI:10.1097/CCE.0000000000001316 2025
Fast Acute Sedation at Intensive Care vs. High-Dose IV Anti-seizure Medication for Treatment of Non-convulsive Status Epilepticus: A Randomized, Multicenter Trial [0.03%]
快速镇静与大剂量抗癫痫药物治疗非惊厥性持续癫痫状态的疗效比较：一项多中心随机对照试验
Camilla Dyremose Cornwall,Henning Piilgaard,Thorbjørn Søndergaard Engedal et al.
Camilla Dyremose Cornwall et al.
Background: The management of refractory status epilepticus (SE) remains an area of low evidence with varying management strategies. Treatment in the ICU is often postponed due to potential complications from sedation, an...
Dynamic Measures of Fluid Responsiveness to Guide Resuscitation in Patients With Sepsis and Septic Shock: A Systematic Review and Meta-Analysis [0.03%]
用于指导脓毒症和脓毒性休克患者复苏的液体反应性动态监测措施的系统评价和meta分析
Jocelyn Wang,Leann Marie Blake,Nicolas Orozco et al.
Jocelyn Wang et al.
Objective: To determine the impact of using dynamic measures of fluid responsiveness in guiding the resuscitation of adult patients with sepsis and septic shock. ...
Jump On It! The Association of Physical Therapy Timing and Frequency With Functional Outcomes in Patients Supported With Extracorporeal Membrane Oxygenation: A Single-Center Retrospective Study [0.03%]
尽早下地活动！体外膜肺氧合患者物理治疗时机和频次与功能结局的相关性研究：单中心回顾性研究
C Christopher Zalesky,Katelyn Whitlock,Briana Krieger et al.
C Christopher Zalesky et al.
Importance: Physical therapy (PT) interventions for patients supported with extracorporeal membrane oxygenation (ECMO) is thought to help preserve independence, but the impact of PT frequency on ECMO recovery is not well ...
Mean Airway Pressure-An Informative but Overlooked Indicator of Mechanical Power [0.03%]
平均气道压力——一个被忽视的但具有参考意义的机械功指标
Michael G Michalik,Philip S Crooke,John J Marini
Michael G Michalik
Mean airway pressure, a monitored variable continuously available on the modern ventilator, is the pressure measured at the airway opening averaged over the time needed to complete the entire respiratory cycle. Mean airway pressure is well ...
Vitamin C Does Not Affect Platelet Counts in Patients With Sepsis: A Post hoc Analysis of the Lessening Organ Dysfunction With Vitamin C Randomized Trial [0.03%]
维生素C不影响脓毒症患者的血小板计数：对照研究的次级分析结果
Mattia M Müller,Ruxandra Pinto,François Lamontagne et al.
Mattia M Müller et al.
Objective: Vitamin C has been linked to alterations in platelet count and aggregation behavior. Given recent findings suggesting an association between vitamin C and adverse outcomes in patients with septic shock, we aime...
Randomized Controlled Trial
Critical care explorations. 2025 Sep 5;7(9):e1310. DOI:10.1097/CCE.0000000000001310 2025
It's Time to Consider How We Should Use Vasopressors, Rather Than Just Which We Should Use [0.03%]
是选择升压药的时候了 还是说 应该考虑如何使用升压药的时候了
Patrick M Wieruszewski,Craig S Jabaley
Patrick M Wieruszewski