Integrating Rapid Cardiopulmonary and Gastric Ultrasound for Emergency Airway Management in Critically Ill Patients: A Case Series of Resident-Performed Echocardiographic Assessment Using Subcostal-Only-View in Physiologically Difficult Airway [0.03%]
急诊困难气道管理的快速心脏肺部和胃部超声整合评估：仅限肋下视图的心超在生理困难气道管理中的居民医师实施.echo评估病例系列研究
Nibras Bughrara,Megalan S Tso,Megan E Weigand et al.
Nibras Bughrara et al.
Objectives: Tracheal intubation in critically ill patients is associated with significant morbidity and mortality. Point-of-care ultrasound (POCUS) may help with hemodynamic optimization and customization of management pl...
Evaluating the Socioeconomic Impact on Critical Care Delivery in Low- and Middle-Income Countries: A Prospective Observational Study From Nigeria [0.03%]
低收入和中等收入国家重症监护递送的社会经济影响评价：尼日利亚的一项前瞻性观察研究
Abayomi Kolawole Ojo,Temitope Akindele Owoniya,Timilehin Mercy Jegede et al.
Abayomi Kolawole Ojo et al.
Objectives: To examine the financial burden of critical care (CC), primary cost drivers, and clinical outcomes associated with CC delivery in low- and middle-income countries (LMICs). ...
Observational Study
Critical care explorations. 2025 Oct 30;7(11):e1337. DOI:10.1097/CCE.0000000000001337 2025
The Impact of an Ex Vivo Pediatric Extracorporeal Membrane Oxygenation Circuit on Sequestration of Antimicrobials [0.03%]
体外儿科膜氧合电路对抗菌药物分布的影响
Michele L Cree,Mohd Hafiz Abdul-Aziz,Emma Haisz et al.
Michele L Cree et al.
Objectives: To determine if common antimicrobials (n = 11) are sequestered or degraded during a pediatric extracorporeal membrane oxygenation (ECMO) simulation. ...
Genetic Variation in the Alternative Complement Pathway Contributes to Individual Susceptibility to Bacteremia and Sepsis [0.03%]
补体系统的遗传变异与败血症的个体易感性有关
Kyle Inman,Jonathan Chernus,Myoungkeun Lee et al.
Kyle Inman et al.
Importance: The alternative complement pathway is a key component of host defense against bacteremia and other infections. However, dysregulated activation can contribute to excessive inflammation and worse clinical outco...
Saki Amagai,Vaishvik Chaudhari,Kaveri Chhikara et al.
Saki Amagai et al.
ICU readmissions remain a critical concern, carrying increased morbidity, mortality, and cost. We examined the epidemiology of unplanned ICU readmissions across 19 hospitals in the Common Longitudinal ICU data Format (CLIF) Consortium from ...
Impact of ICU Length of Stay and Illness Severity on Rehabilitation Progress and Functional Recovery: A Secondary Analysis of the Japanese Rehabilitation and Risk Factors on the Post-Intensive Care Syndrome (J-RELIFE) Prospective Registry [0.03%]
重症监护室住院时间、疾病严重程度对康复进程和功能恢复影响的二次分析：日本重症监护综合征康复与危险因素前瞻性登记研究（J-RELIFE）
Yorihide Yanagita,Yuki Iida,Shinichi Watanabe et al.
Yorihide Yanagita et al.
Importance: Although survival rates in ICUs have improved, ICU length of stay is increasing, particularly among critically ill patients requiring prolonged mechanical ventilation. These patients often face challenges in e...
Multicenter Study
Critical care explorations. 2025 Oct 17;7(10):e1334. DOI:10.1097/CCE.0000000000001334 2025
Relationship Between Phenotyping and Individualized Absolute Risk Differences in Sepsis: A Secondary Analysis of Two Approaches in Two Multicenter Trials [0.03%]
脓毒症表型与个体化绝对风险差异之间的关系：来自两个多中心试验的两种方法的二次分析
Victor B Talisa,Sachin P Yende,Derek C Angus et al.
Victor B Talisa et al.
Objectives: Sepsis trials likely include patients who vary in response to therapeutic interventions. The optimal approach to identify such differences in treatment response remains unclear. Estimating individualized absol...
Randomized Controlled Trial
Critical care explorations. 2025 Oct 13;7(10):e1332. DOI:10.1097/CCE.0000000000001332 2025
Physiological Signal Entropy in Pediatric Traumatic Brain Injury: Looking Beyond the Obvious: A STARSHIP Study [0.03%]
儿童创伤性脑损伤的生理信号熵：超越表面现象：一项STARSHIP研究
Stefan Yu Bögli,Claudia Ann Smith,Peter Hutchinson et al.
Stefan Yu Bögli et al.
Objectives: Multimodality monitoring based prognostication in pediatric traumatic brain injury (TBI) relies heavily on the evaluation of instantaneous and easily interpretable monitoring values. Entropy quantifies the lev...
Observational Study
Critical care explorations. 2025 Oct 13;7(10):e1333. DOI:10.1097/CCE.0000000000001333 2025
Augmenting Mortality Prediction in Critically Ill Adults With Medication Data and Machine Learning Models [0.03%]
基于药物数据和机器学习模型增强重症成人患者死亡率预测
Brian Murray,Tianyi Zhang,Zhetao Chen et al.
Brian Murray et al.
Background: Mortality prediction in ICU adults is only marginally improved when medication regimen complexity (MRC) data is incorporated into traditional regression models. Machine learning (ML) may improve this predictio...
Biomarkers of Microcirculatory Dysfunction in Sepsis: A Pilot Prospective Observational Study [0.03%]
一项前瞻性观察研究：脓毒症微循环障碍的生物标志物
August Longino,Katharine Martin,Stephen Bourland et al.
August Longino et al.
Context: To evaluate and compare sublingual microscopy (SLM) to urinary glycosaminoglycan (GAG) assays, dimethylmethylene blue (DMMB) assay, and liquid chromatography tandem mass spectrometry (LC-MS/MS) quantification of ...
Observational Study
Critical care explorations. 2025 Oct 9;7(10):e1324. DOI:10.1097/CCE.0000000000001324 2025