Urine Olfactomedin 4 Predicts Furosemide Response and Kidney Replacement Therapy in Critically Ill Children [0.03%]
尿液olfactomedin 4预测重症儿童呋塞米反应和肾脏替代治疗
Denise C Hasson,Imogen Clover-Brown,Diana Zepeda-Orozco et al.
Denise C Hasson et al.
Objectives: To test whether urine olfactomedin 4 (uOLFM4) can predict furosemide responsiveness in patients at high risk for acute kidney injury (AKI) early in the PICU course. A secondary outcome was prediction of kidney...
Observational Study
Critical care explorations. 2025 Dec 3;7(12):e1356. DOI:10.1097/CCE.0000000000001356 2025
The POETIC (PrOcess Evaluation of Trials In Critical care) Framework: A Structured Approach for Designing and Conducting Process Evaluations in Critical Care Trials [0.03%]
POETIC（重症监护临床试验结果评价）框架：在重症监护试验中设计和开展过程评估的结构化方法
Lydia M Emerson,Daniel F McAuley,Bronagh Blackwood et al.
Lydia M Emerson et al.
Background: A process evaluation systematically examines how an intervention is delivered, including activities, procedures, and contextual factors influencing implementation. Existing process evaluation frameworks were p...
Long-Term Functional and Quality-of-Life Outcomes in Survivors of Refractory Cardiogenic Shock Treated With Venoarterial Extracorporeal Membrane Oxygenation [0.03%]
静脉动脉体外膜肺氧合治疗难治性心源性休克后患者长期功能及生活质量预后研究
Sofia Ortuno,Delphine Bachelet,Olivier Varnet et al.
Sofia Ortuno et al.
Importance: Long-term functional outcomes and health-related quality of life (HRQoL) in survivors of cardiogenic shock treated with venoarterial extracorporeal membrane oxygenation (ECMO) remain poorly understood. ...
Observational Study
Critical care explorations. 2025 Dec 2;7(12):e1359. DOI:10.1097/CCE.0000000000001359 2025
Fast, Accurate Assignment of Clinical Diagnoses From Patient Notes by a Large Language Model: Critical Pediatric Pneumonia as a Use Case [0.03%]
快速准确地使用大型语言模型从患者记录中分配临床诊断：以儿科重症肺炎为例
Blake Martin,Marisa Payan,Jaime LaVelle et al.
Blake Martin et al.
Objective: To determine the accuracy of a custom version of the generative pretrained transformer (GPT)-4o large language model (LLM) in identifying PICU admissions with vs. without bacterial pneumonia using clinical note...
Effect of Neuromuscular Electrical Stimulation for Older Critically Ill Patients in the ICU: A Randomized Controlled Trial [0.03%]
重症监护病房老年危重患者的神经肌肉电刺激疗效的随机对照试验
Kazuhiro Yokobatake,Hiroaki Kitaoka,Atsushi Morizane et al.
Kazuhiro Yokobatake et al.
Objectives: In the ICU, the optimal patient population for neuromuscular electrical stimulation (NMES) and the most appropriate evaluation tools remain unclear. This study aimed to assess whether combining early mobilizat...
Randomized Controlled Trial
Critical care explorations. 2025 Nov 25;7(12):e1345. DOI:10.1097/CCE.0000000000001345 2025
Ward-Based High-Flow Nasal Cannula Led by the Medical Emergency Team: A Pragmatic Model for Resource Stewardship [0.03%]
基于医疗紧急团队的病房高流量鼻导管吸氧治疗：一种实用的医疗资源管理模型
Imran Khalid,Basel Ghurm Alshehri,Raafey Imran et al.
Imran Khalid et al.
High-flow nasal cannula (HFNC) for acute hypoxemic respiratory failure is typically restricted to ICUs. We evaluated a ward-based, medical emergency team (MET)-supervised HFNC protocol (flow ≤ 40 L/min, Fio2 ≤ 0.40) with 2-/4-/8-hour nurs...
National Experience With Tracheostomy in Neonates Undergoing Congenital Heart Surgery: A Multicenter Analysis [0.03%]
先天性心脏病手术新生儿气管切开的国家经验：一项多中心分析
Hosam F Ahmed,Muhammad Faateh,Kevin Kulshrestha et al.
Hosam F Ahmed et al.
Objectives: Our aim was to describe trends in tracheostomy utilization in infants requiring congenital heart surgery (CHS) during their index admission with specific focus on clinical and financial outcomes. ...
Multicenter Study
Critical care explorations. 2025 Nov 24;7(12):e1357. DOI:10.1097/CCE.0000000000001357 2025
Metabolomics for the Diagnosis of Secondary Infections in Critically Ill Patients With COVID-19 [0.03%]
代谢组学在重症新冠肺炎患者继发感染诊断中的应用
Gordan McCreath,Clément Regnault,Gavin J Blackburn et al.
Gordan McCreath et al.
Objectives: Secondary infections are a common occurrence in critically ill COVID-19 patients. These are difficult to identify, and antibiotic usage is high in this population. Identification of biomarkers for secondary in...
Multicenter Study
Critical care explorations. 2025 Nov 6;7(11):e1336. DOI:10.1097/CCE.0000000000001336 2025
Acceptability of Tele-Critical Care Consultation for Patients at Risk of ICU Admission [0.03%]
危重症监护病房高风险患者远程会诊的适用性研究
Bradley A Fritz,Christopher Palmer,Hosam Arammash et al.
Bradley A Fritz et al.
Importance: Current approaches for bringing critical care expertise to hospital floors to support deteriorating patients are limited by intensivist availability, costs, and scalability. Using existing tele-critical care c...
NeuroRecovery Clinics: A Survey to Understand the Current Landscape and Opinions of Post-NeuroICU Clinics [0.03%]
神经康复门诊：一项调查当前神经重症监护病房后门诊格局和意见的研究
Matthew N Jaffa,Julia M Carlson
Matthew N Jaffa
Objectives: Survival following severe acute neurologic injury (SANI) is increasing. The complexities of caring for these patients are vast and gaps have been highlighted in post-acute care follow-up. While the development...