A Co-Designed Post-ICU Follow-Up Pathway Is Feasible and May Be Associated With Improved Psychosocial Recovery for Patients and Their Caregivers: Outcomes From the IMPACT-ICU Single-Center Randomized Controlled Trial [0.03%]
一项针对重症监护病房患者的联合设计的出院后随访路径是可行的，并且可能有助于改善患者及其照护者的心理健康恢复：来自IMPACT-ICU单中心随机对照试验的结果
Natasha A Jawa,Michaela Hanley,Akasham Rajagopaul et al.
Natasha A Jawa et al.
Objectives: Post-intensive care syndrome (PICS) and PICS-family (PICS-F) lead to lasting physical, cognitive, and psychologic challenges among survivors of critical illness and their caregivers. It is unclear how best to ...
Randomized Controlled Trial
Critical care explorations. 2026 Aug 6;8(8):e1448. DOI:10.1097/CCE.0000000000001448 2026
High-Flow Nasal Cannula Versus Noninvasive Ventilation for Prevention of Reintubation in High-Risk Critically Ill Patients (HIGH-FLOW OXY): An Informative Systematic Review and Meta-Analysis [0.03%]
高流量鼻导管与无创通气预防高危重症患者拔管后再插管的系统评价和 meta 分析（ HIGH-FLOW OXY）
Nhan Nguyen,Nathalia Alves de Barros E Lyra,David Downes et al.
Nhan Nguyen et al.
Objectives: Optimal postextubation respiratory support for critically ill patients at high risk of reintubation remains uncertain. We aimed to compare the efficacy of high-flow nasal cannula (HFNC) vs. noninvasive ventila...
Severity and Clinical Outcomes Among ICU Patients With Diabetic Ketoacidosis: An Analysis of the Japanese Intensive Care Patient Database [0.03%]
日本重症监护患者数据库中的糖尿病酮症酸中毒的严重程度及临床结局分析
Reina Miyazaki,Hiromu Okano,Shunsaku Goto et al.
Reina Miyazaki et al.
Importance: Diabetic ketoacidosis (DKA) is an acute metabolic emergency characterized by hyperglycemia, ketosis, and acidosis due to insulin deficiency. While ICU admission is frequently considered for DKA, admission thre...
Observational Study
Critical care explorations. 2026 Aug 5;8(8):e1449. DOI:10.1097/CCE.0000000000001449 2026
Early Total Bilirubin Trajectories During the First 72 Hours After ICU Admission With Mechanical Ventilation and Short-Term Mortality: A Multicenter Cohort Study [0.03%]
ICU机械通气患者入院后前72小时总胆红素轨迹与短期死亡率多中心队列研究
Takuya Nishino,Hiroshi Mase,Shinji Sugita et al.
Takuya Nishino et al.
Objectives: To determine whether early total bilirubin (T-Bil) trajectories during the first 72 hours after intubation identify trajectory-defined groups with distinct prognostic profiles associated with short-term mortal...
Multicenter Study
Critical care explorations. 2026 Aug 5;8(8):e1447. DOI:10.1097/CCE.0000000000001447 2026
Safety and Feasibility of Bedside Electrical Impedance Tomography With Hypertonic Saline Contrast for Assessing Pulmonary Perfusion in Mechanically Ventilated Children With Acute Respiratory Distress Syndrome: A Pilot Study [0.03%]
床旁高渗盐水电阻抗断层成像技术评估急性呼吸窘迫综合征机械通气儿童肺灌注的安全性与可行性：一项试点研究
Jing Zhang,Shuang Liu,Ning Li et al.
Jing Zhang et al.
Importance: Electrical impedance tomography (EIT) offers a noninvasive, radiation-free imaging alternative, but its perfusion evaluation capability in children is understudied. Hypertonic saline-enhanced EIT may address t...
Observational Study
Critical care explorations. 2026 Aug 5;8(8):e1445. DOI:10.1097/CCE.0000000000001445 2026
The Effect of Transpulmonary Pressure-Guided Positive End-Expiratory Pressure Titration on Pulmonary Arterial Compliance in Acute Respiratory Distress Syndrome Patients: A Single-Center, Randomized Controlled Pilot Pathophysiological Study [0.03%]
基于跨肺压滴定调节呼气末正压对急性呼吸窘迫综合征患者肺动脉顺应性的影响：一项单中心随机对照生理学研究
Xiao Tang,Ting Li,Hua Yang et al.
Xiao Tang et al.
Objectives: To compare the function of positive end-expiratory pressure (PEEP) titration guided by transpulmonary pressure (Ptp) with traditional lung-protective ventilation to optimize pulmonary arterial compliance (Cpa)...
Randomized Controlled Trial
Critical care explorations. 2026 Aug 5;8(8):e1461. DOI:10.1097/CCE.0000000000001461 2026
Implementing a Green ICU Pathway Across a Large U.S. Health System: An Observational Study [0.03%]
在美国大型医疗体系中实施绿色ICU路径的观察性研究
Faisal N Masud,Adel H Khan,Jason F Fischer et al.
Faisal N Masud et al.
Importance: ICUs contribute substantial environmental impact within the healthcare industry, yet few practical solutions have been published to implement environmentally sustainable practices. ...
Observational Study
Critical care explorations. 2026 Aug 5;8(8):e1450. DOI:10.1097/CCE.0000000000001450 2026
Severe Diltiazem Poisoning Managed With CytoSorb Hemoadsorption and Supportive Therapies: A Case Report [0.03%]
采用体外血液吸附联合支持治疗重度地尔硫卓中毒一例报告
Juul M Cox,Julia A M Verwaaijen,Ruben M F Hendriks et al.
Juul M Cox et al.
Background: Severe intoxication with nondihydropyridine calcium channel blockers, such as diltiazem, is associated with high morbidity and mortality. Evidence supporting extracorporeal treatment strategies remains limited...
Amino Acid Deficiency Secondary to Continuous Venovenous Hemofiltration in Acute Decompensation of Organic Acidemias: An Anabolic Dead End? [0.03%]
连续静脉-静脉血液滤过导致有机酸尿症急性恶化患者的氨基酸缺乏：生理性合成的死胡同吗？
Chloé Grosyeux,Noémie Cammiciotto,Elise Jeannesson et al.
Chloé Grosyeux et al.
Objective: To evaluate the impact of continuous renal replacement therapy (CRRT) on plasma amino acid (AA) concentrations in patients with acute metabolic decompensation of organic acidemias (OAs), and to explore whether ...
Observational Study
Critical care explorations. 2026 Aug 3;8(8):e1413. DOI:10.1097/CCE.0000000000001413 2026
When End-of-Life Becomes the Beginning of New Life: Application of the Society of Critical Care Medicine Clinical Practice Guidelines on Adult End-of-Life Care in the ICU to the Setting of Donation After Circulatory Death [0.03%]
当生命终结成为新生命的开始：重症医学会成人临终关怀临床实践指南在心脏死亡器官捐献中的应用
Ian M Oppenheim,Rita N Bakhru,Carolina B Maciel et al.
Ian M Oppenheim et al.
The recently published Society of Critical Care Medicine Guidelines on Adult End-of-Life Care in the ICU provide a detailed and well-thought-out approach to a vital component of critical care, although they explicitly refrain from discussin...