CasPINS: an integrated web-based platform for CRISPR/TALEN gRNA design, primer generation, and indel decomposition analysis [0.03%]
CasPINS：一个集成了CRISPR / TALEN gRNA设计、引物生成和缺失分析的网络平台
Rinki Dasgupta,Kaushik Das
Rinki Dasgupta
Genome editing researchers currently navigate multiple disconnected tools for guide RNA (gRNA) design, primer generation, and editing analysis-a fragmented workflow that introduces errors and limits reproducibility. CasPINS (Cas-Primer-Inde...
TelomereHunter2: improved in silico telomere analysis software for precision oncology and single-cell studies [0.03%]
TelomereHunter2：改进的基于计算的端粒分析软件，用于精准肿瘤学和单细胞研究
Ferdinand Popp,Nicola Biondi,Urška Pogorevčnik et al.
Ferdinand Popp et al.
Motivation: Telomere biology plays a critical role in multiple biological processes including carcinogenesis, aging, and genome stability. With increasing availability of DNA-sequence datasets, telomere length and composi...
wavess 1.2: presenting an HLA-aware within-host virus sequence simulation framework [0.03%]
waves 1.2：呈现一个HLA感知的宿主内病毒序列模拟框架
Zena Lapp,Thomas Leitner
Zena Lapp
Motivation: Understanding how virus sequences are shaped by selection can inform vaccine design and transmission inference. Modeling within-host evolution to interrogate these questions requires a detailed mechanistic fra...
Mingon Kang,Eunyoung Jang,Tesfaye B Mersha
Mingon Kang
Multi-omics interactions, including intra- and inter-omics interactions as well as socio-environmental influences, are key to uncovering molecular mechanisms that may be missed by individual omics analysis or conventional integration approa...
Annotation of glycoside hydrolases in unassembled metagenomes using CAZyOGH [0.03%]
基于CAZyOGH的宏基因组非组装数据中糖基水解酶注释方法
Nicholas G Griffin,Alison E Hughes,Daniel S Erdody et al.
Nicholas G Griffin et al.
Motivation: Functional characterization of microbiomes often relies on the sequencing of metagenomic DNA extracted from environmental samples, with current approaches using metagenome-assembled genomes (MAGs). Although gl...
BioGraphX: bridging the sequence-structure gap via physicochemical graph encoding for interpretable subcellular localization prediction [0.03%]
BioGraphX：通过物理化学图编码建立序列-结构联系以实现可解释的亚细胞定位预测
Abubakar Saeed,Waseem Abbas
Abubakar Saeed
Motivation: Computational protein subcellular localization prediction is vital for understanding cellular mechanisms and disease treatments. However, current methods lack interpretability: they predict where a protein loc...
Samuel Pis-Vigil,María González-Pereira,Magda R Hamczyk et al.
Samuel Pis-Vigil et al.
Motivation: Proportional Venn diagrams provide a compact representation of the relationships between sets. Each relationship is represented with a region whose area reflects the number of elements shared by a given combination of sets. This...
Correction to: gLeiden: accelerated community detection algorithms using directed and undirected graphs on GPUs [0.03%]
gLeiden算法修正：基于有向和无向图的gpu加速社区检测算法纠正 limburg 不懂为什么是limburg，请核对信息，其他部分为正确的翻译。
[This corrects the article DOI: 10.1093/bioadv/vbaf327.]. © The Author(s) 2026. Published by Oxford University Press.
Published Erratum
Bioinformatics advances. 2026 Jul 9;6(1):vbag177. DOI:10.1093/bioadv/vbag177 2026
Identifying novel Japanese heart failure variants via endothelial cis-regulatory element analysis [0.03%]
通过内皮细胞顺式调控元件分析识别日本心力衰竭的新变异型
Momoko Hamano,Seitaro Nomura,Kaoru Ito et al.
Momoko Hamano et al.
Motivation: The detailed molecular mechanisms and disease risk factors for heart failure, especially in the Japanese population, remain to be identified. In this study, we developed a trans-omics approach integrating mult...
stackPredAMR-a stacked random forest approach improves AMR phenotype prediction for multiple species and antimicrobial agents [0.03%]
一种堆叠随机森林方法可提高多物种和抗菌剂的耐药表型预测性能
Julian Welling,Miriam Balzer,Leah Consten et al.
Julian Welling et al.
Motivation: Antimicrobial resistance is a growing global threat, creating a need for rapid and accurate antimicrobial susceptibility testing. Current phenotypic antimicrobial susceptibility testing methods rely on prior i...