Evidente-a visual analytics tool for data enrichment in SNP-based phylogenetic trees [0.03%]
基于SNP的系统发育树的数据丰富型视觉分析工具
Mathias Witte Paz,Theresa A Harbig,Kay Nieselt
Mathias Witte Paz
Motivation: A common practice in the analysis of pathogens and their strains is using single-nucleotide polymorphisms (SNPs) to reconstruct their evolutionary history. However, genome-wide SNP-based phylogenetic trees are...
ImaGene: a web-based software platform for tumor radiogenomic evaluation and reporting [0.03%]
基于网络的肿瘤影像基因组学评估和报告的软件平台IMA gene
Shrey S Sukhadia,Aayush Tyagi,Vivek Venkataraman et al.
Shrey S Sukhadia et al.
Summary: Radiographic imaging techniques provide insight into the imaging features of tumor regions of interest, while immunohistochemistry and sequencing techniques performed on biopsy samples yield omics data. Relations...
PhenoComb: a discovery tool to assess complex phenotypes in high-dimensional single-cell datasets [0.03%]
PhenoComb：一种评估高维单细胞数据集中复杂表型的发现工具
Paulo E P Burke,Ann Strange,Emily Monk et al.
Paulo E P Burke et al.
Motivation: High-dimensional cytometry assays can simultaneously measure dozens of markers, enabling the investigation of complex phenotypes. However, as manual gating relies on previous biological knowledge, few marker c...
More accurate estimation of cell composition in bulk expression through robust integration of single-cell information [0.03%]
通过单细胞信息的稳健集成更准确地估算批量表达中的细胞组成比例
Ali Karimnezhad
Ali Karimnezhad
Motivation: The rapid single-cell transcriptomic technology developments have led to an increasing interest in cellular heterogeneity within cell populations. Although cell-type proportions can be obtained directly from s...
The network makeup artist (NORMA-2.0): distinguishing annotated groups in a network using innovative layout strategies [0.03%]
基于创新布局策略的网络化妆师（NORMA-2.0）：利用新颖的布线策略区分注释组
Evangelos Karatzas,Mikaela Koutrouli,Fotis A Baltoumas et al.
Evangelos Karatzas et al.
Motivation: Network biology is a dominant player in today's multi-omics era. Therefore, the need for visualization tools which can efficiently cope with intra-network heterogeneity emerges. ...
reComBat: batch-effect removal in large-scale multi-source gene-expression data integration [0.03%]
一种在大规模基因表达数据整合中消除批次效应的工具：reComBat
Michael F Adamer,Sarah C Brüningk,Alejandro Tejada-Arranz et al.
Michael F Adamer et al.
Motivation: With the steadily increasing abundance of omics data produced all over the world under vastly different experimental conditions residing in public databases, a crucial step in many data-driven bioinformatics a...
PACKMAN-Molecule: Python toolbox for structural bioinformatics [0.03%]
PACKMAN-Molecule：结构生物信息学的Python工具箱
Pranav M Khade,Robert L Jernigan
Pranav M Khade
PACKMAN-molecule is a Structural Bioinformatics toolbox in the form of an Application Programming Interface that contains several utilities that can be used for structural bioinformatics applications. It has already been used in several app...
E-learning strategies from a bioinformatics postgraduate programme to improve student engagement and completion rate [0.03%]
生物信息学研究生课程中的在线学习策略能够提高学生参与度和完成率？
Andrés Garzón,Alejandro Rubio,Antonio J Pérez-Pulido
Andrés Garzón
Motivation: E-learning is the standard solution adopted in transnational study programmes for which multiple face-to-face learning places are not an option. Bioinformatics is compatible with e-learning because its resourc...
Shuffle & untangle: novel untangle methods for solving the tanglegram layout problem [0.03%]
打乱与解开：解决缠绕图布局问题的新方法研究
Nghia Nguyen,Kurdistan Chawshin,Carl Fredrik Berg et al.
Nghia Nguyen et al.
Motivation: A tanglegram is a plot of two-tree-like diagrams, one facing the other, and having their labels connected by inter-tree edges. These two trees, which could be both phylogenetic trees and dendrograms stemming f...
LIQUORICE: detection of epigenetic signatures in liquid biopsies based on whole-genome sequencing data [0.03%]
基于全基因组测序数据在液体活检中检测表观遗传特征的工具-Liquorice
Peter Peneder,Christoph Bock,Eleni M Tomazou
Peter Peneder
Summary: Fragmentation patterns of cell-free DNA reflect the chromatin structure of the cells from which these fragments are derived. Nucleosomes protect the DNA from fragmentation, resulting in decreased sequencing cover...