BLIT: an R package for seamless integration of command-line bioinformatics tool universe [0.03%]
BLIT：一个用于无缝集成命令行生物信息学工具宇宙的R包
Jia Ding,Yun Peng,Ruochen Wei et al.
Jia Ding et al.
Motivation: Modern computational biology relies heavily on command-line tools that underpin analytical workflows, yet integrating these tools into R-based analyses poses substantial challenges for reproducibility, especia...
New algorithms for unsupervised cell clustering from scRNA-seq data [0.03%]
新的无监督细胞聚类算法用于scRNA-seq数据
Melissa Robles,Jorge Díaz-Riaño,Cristhian Forigua et al.
Melissa Robles et al.
The identification of cell types is a basic step of pipelines for Single-Cell RNA sequencing (scRNA-seq) data analysis. However, unsupervised clustering of cells from scRNA-seq data has multiple challenges: high dimensionality, sparseness o...
FetchM: streamlining genome and metadata integration for bacterial comparative genomics [0.03%]
FetchM：简化细菌比较基因组学的基因组和元数据集成
Tasnimul Arabi Anik,Peter Kjær Mackie Jensen,Anowara Begum
Tasnimul Arabi Anik
Motivation: Large-scale bacterial comparative genomics require comprehensive metadata describing genome assemblies and their biological context. While NCBI Genome holds the assemblies and BioSample stores key contextual f...
Love-thy-neighbor: neural networks for tracking and lineage tracing in budding yeast [0.03%]
爱邻法则：接合酵母细胞分裂跟踪与谱系重建的神经网络方法
Marija Zelic,Vojislav Gligorovski,Farzaneh Labbaf et al.
Marija Zelic et al.
Tracking and lineage tracing are widely needed tasks in biological image analysis. For cells that grow and divide, tracking is challenging because cells change in number, shape, and size throughout a recording. Longer intervals between imag...
20 Years of the ISCB Student Council Symposium: shaping computational biology and future leaders [0.03%]
国际计算生物学学生理事会二十周年：铸就计算生物学者与未来领袖
Miguel Fernandez-Martin,Ana Castillo-Orozco,Miriam Poley-Gil et al.
Miguel Fernandez-Martin et al.
Over the past two decades, the Student Council Symposium (SCS), the flagship event of the ISCB Student Council, has grown into a vital forum for early-career researchers in computational biology. Since its inception in 2005, the SCS has ser...
Martín Méndez,Francisco Javier Moreno,Florencio Pazos
Martín Méndez
Motivation: The current trend to incorporate new protein sources to the diet, mostly from plants, requires a safety assessment of these polypeptides when used as food. Part of that safety evaluation involves assessing the...
Predicting progression of Alzheimer's disease using blood-based multi-omics data [0.03%]
基于血液的组学数据预测阿尔茨海默病进展
Yashu Vashishath,Bizhan Alipour Pijani,Neha Goud Baddam et al.
Yashu Vashishath et al.
Motivation: Early prediction of Alzheimer's disease (AD) progression from mild cognitive impairment (MCI) remains a major challenge, particularly when relying on non-invasive biomarkers. Identifying individuals with progr...
One health analysis of antimicrobial resistance in Escherichia coli from humans, animals, and the environment [0.03%]
基于人类、动物和环境中的大肠杆菌的一体化抗菌素耐药性分析
Beatus Lyimo
Beatus Lyimo
Summary: Antimicrobial resistance (AMR) poses a critical public health threat, with evidence suggesting the transfer of resistance genes between humans, animals, and the environment. This study investigates the distributi...
Computational design of class II MHC binding peptide with sequence-based evolution information [0.03%]
基于序列进化信息的Ⅱ型MHC结合肽计算设计方法研究
Ying Cao,Yuqing Li,Weitong Ren et al.
Ying Cao et al.
MHCII-peptide binding plays a vital role in immunology. MHCII molecules are primarily expressed on the surface of antigen presenting cells where they capture and present exogenous antigen peptides to helper T cells, thereby activating humor...
DoTools: a cross platform framework to streamline common single cell workflows [0.03%]
DoTools：一个跨平台框架，可简化常见的单细胞工作流程
Mariano Ruz Jurado,David Rodriguez Morales,Lukas Zanders et al.
Mariano Ruz Jurado et al.
Motivation: Throughout the years, single-cell RNA sequencing (scRNA-seq) has become a standard approach for characterising transcriptomic changes associated with diseases and other biological conditions. However, the rapi...