Decompensated Liver Cirrhosis Research Network (UK-CLIF): Building consensus for hepatology trials in the UK [0.03%]
英国终期肝病研究网络（UK-CLIF）：在英国建立肝病试验共识
Helen Crisp,Oliver Tavabie,Yvanne Enever et al.
Helen Crisp et al.
Liver disease is a major, and increasing, cause of death in the UK. The UK Chronic Liver Failure network (UK-CLIF) was developed as a multi-stakeholder network with the aim to advance cirrhosis research, with emphasis on geographical areas ...
Natural language processing for detecting adverse drug events: A systematic review protocol [0.03%]
用于检测药物不良事件的自然语言处理系统评价方案
Imane Guellil,Jinge Wu,Aryo Pradipta Gema et al.
Imane Guellil et al.
Background: Detecting Adverse Drug Events (ADEs) is an emerging research area, attracting great interest in the research community. Better anticipatory management of predisposing factors has considerable potential to impr...
Educational outcomes of children with major congenital anomalies: Study protocol for a population-based cohort study using linked hospital and education data from England [0.03%]
重大先天畸形儿童的教学效果：一项基于人群的队列研究方案，使用来自英格兰的链接医院和教育数据
Joachim Tan,Ayana Cant,Kate Lewis et al.
Joachim Tan et al.
Background: Major congenital anomalies (CAs) affect around 2% of live births and are a primary cause of infant mortality, childhood morbidity and long-term disability, often requiring hospitalisation and/or surgery. Child...
The Eczema Bathing Study: Weekly versus daily bathing for people with eczema? Protocol of an online, randomised controlled trial [0.03%]
特应性皮炎沐浴研究：特应性皮炎患者每周沐浴与每日沐浴哪种较好？一项在线随机对照试验的方案
Wei Chern Gavin Fong,Laura Howells,Ingrid Muller et al.
Wei Chern Gavin Fong et al.
Background: A priority setting partnership for eczema (syn atopic eczema, atopic dermatitis) has identified that bathing frequency is a key area of patient interest. However, there are nolarge, high-quality randomised con...
Pulmonary aspiration during pregnancy or immediately postpartum in the UK: A population-based case-control study [0.03%]
英国孕期或产后早期肺吸入情况的基于人群的病例对照研究
Nuala Lucas,Alison Gooda,Ruth Tunn et al.
Nuala Lucas et al.
Background: Pulmonary aspiration of gastric contents is the most frequent cause of death associated with complications of airway management during general anaesthesia. Pregnancy increases aspiration risk owing to factors ...
Pharmacist-led DE-eSCALation of opioids post-surgical dischargE (DESCALE) - A multi-centre, non-randomised, feasibility study protocol [0.03%]
术后出院后以药剂师为主导的止痛药物DE-eSCALation临床可行性研究方案(DESCALE)
Emma L Veale,Johanna Theron,Melanie Rees-Roberts et al.
Emma L Veale et al.
Background: Opioids are frequently prescribed for short-term acute pain following surgery. Used appropriately, opioids deliver extremely favourable pain relief. Used longer than 90-days, however, can result in health comp...
Mapping decision-making pathways: Determination of intervention entry points for diagnostic tests in suspected serious infection [0.03%]
决策途径的绘制：疑似重症感染诊断试验干预切入点的确立
Raasti Naseem,Nicola Howe,Sara Pretorius et al.
Raasti Naseem et al.
Background: PROTECT ( Platform Randomised evaluation of clinical Outcomes using novel TEChnologies to optimise antimicrobial Therapy) has brought together a team of researchers to design a platform trial to rapidly evalua...
Protocol for a prospective observational cohort study of cutaneous leishmaniasis in Ethiopia [0.03%]
埃塞俄比亚皮肤利什曼病前瞻性队列研究方案
Amel Beshir Mohammed,Fewzia Shikur Mohammed,Feleke Tilahun Zewdu et al.
Amel Beshir Mohammed et al.
Background: Cutaneous leishmaniasis (CL) is a skin neglected tropical disease, with an estimated 40,000 new cases each year in Ethiopia. CL causes ulcers, nodules, and plaques on the skin, and in some instances the destru...
Temporal Trends in Parkinson's Disease Related Mortality from 1999-2020: A National Analysis [0.03%]
1999至2020年帕金森病相关死亡率的 temporal trends：一项国家层面分析研究
Balamrit Singh Sokhal,Sowmya Prasanna Kumar Menon,Thomas Shepherd et al.
Balamrit Singh Sokhal et al.
Introduction: Parkinson's disease (PD) is the most common neurodegenerative movement disorder and is associated with significant disability. The prevalence is rising, and studies have reported potential sex and race dispa...
Patient and public involvement in the design and protocol development for a platform randomised trial to evaluate diagnostic tests to optimise antimicrobial therapy (PROTECT) [0.03%]
受试者和公众参与抗菌药物治疗优化平台随机试验（(PROTECT)）的设计及方案制定中
Martina Svobodova,Liza Keating,Melanie Gager et al.
Martina Svobodova et al.
Background: Our patient and public involvement activities were part of a project aiming to develop a master protocol and National Institute for Health and Care research application for the PROTECT trial aiming to assess t...