Impact of special educational needs provision on hospital utilisation, school attainment and absences for children in English primary schools stratified by gestational age at birth: A target trial emulation study protocol [0.03%]
英国初等教育中特殊教育需求供给对住院利用率、学习成绩及缺课情况影响的分胎龄目标试验仿真研究方案
Vincent G Nguyen,Kate Marie Lewis,Ruth Gilbert et al.
Vincent G Nguyen et al.
Introduction: One third of children in English primary schools have additional learning support called special educational needs (SEN) provision, but children born preterm are more likely to have SEN than those born at te...
Diagnostic accuracy of serological and imaging tests used in surveillance for hepatocellular carcinoma in adults with cirrhosis: a systematic review protocol [0.03%]
用于肝硬化成人中开展肝细胞癌监测的血清学和影像学检查诊断准确性系统评价方案
Libby Sadler,Hayley Jones,Penny Whiting et al.
Libby Sadler et al.
Background: Liver cirrhosis is the largest risk factor for developing hepatocellular carcinoma (HCC), and surveillance is therefore recommended among this population. Current guidance recommends surveillance with ultrasou...
Mobility and strength training with and without protein supplements for pre-frail or frail older adults with low protein intake: the Maximising Mobility and Strength Training (MMoST) feasibility randomised controlled trial protocol [0.03%]
低蛋白摄入的前期脆弱或脆弱老年人进行蛋白质补充或不补充蛋白质的力量和体能训练：MMoST可行性随机对照试验方案
Kavita Biggin,Ioana R Marian,Sarah E Lamb et al.
Kavita Biggin et al.
Background Frailty is a common syndrome affecting older people and puts them at risk of hospitalisation, needing care or death. First signs of frailty include reduced muscle strength and mobility decline. A key cause of mobility decline as ...
Qualitative study of experience of acceptance and commitment therapy (ACT+) amongst Survivors' Rehabilitation Evaluation after Cancer (SURECAN) trial participants and therapists: A protocol [0.03%]
SURECAN试验参与者和治疗师对增强型接纳承诺疗法(ACT+)体验的定性研究：方案描述
Sheila Donovan,Trudie Chalder,Dipesh Gopal et al.
Sheila Donovan et al.
Background: This interview study forms part of a mixed methods process evaluation of the Survivors' Rehabilitation Evaluation after Cancer (SURECAN) trial to understand the experiences of participants (who are living with...
Patient reported outcomes and recruitment rates following the introduction of principled patient information leaflets (PrinciPILs): Protocol for a meta-analysis [0.03%]
一种基于原则的患者信息手册对患者报告结果和参与率的影响：系统评价与meta分析方案
Jeremy Howick,Martina Svobodova,Shaun Treweek et al.
Jeremy Howick et al.
Background: The way potential benefits and harms of trial interventions are shared within patient information leaflets (PILs) varies widely and may cause unnecessary harms ("nocebo effects"). The aim of this meta-analysis...
Enablers and barriers to engaging under-served groups in research: Survey of the United Kingdom research professional's views [0.03%]
英国研究人员关于促进和阻碍科研中服务不足群体参与的推动因素和障碍因素调查的观点
Dorothy Coe,Theophile Bigirumurame,Meera Burgess et al.
Dorothy Coe et al.
Background: There is a known lack of diversity in research participant populations. This impacts on the generalisability of findings and affects clinician prescribing. In the United Kingdom the research community defines ...
A randomised crossover trial of tezacaftor-ivacaftor for gut dysfunction in cystic fibrosis with magnetic resonance imaging (MRI) outcomes: a pilot study [0.03%]
磁共振成像结果导向的针对囊性纤维化患者胃肠功能障碍的tezacaftor-ivacaftor随机交叉试验：一项概念验证研究
Christabella Ng,Neele S Dellschaft,Caroline Hoad et al.
Christabella Ng et al.
Background: People with cystic fibrosis (CF) can experience recurrent chest infections, pancreatic exocrine insufficiency and gastrointestinal symptoms. New cystic fibrosis transmembrane conductance regulator (CFTR) modul...
A Randomised Controlled Trial of Early Vitrectomy and Intravitreal Antibiotics for Post-operative Exogenous Endophthalmitis (EVIAN study): study protocol for a feasibility trial [0.03%]
早期玻璃体切割术与玻璃体内注射抗生素治疗术后外源性眼内炎的随机对照研究（EVIAN研究）：可行性试验方案
Mahiul Muhammed Khan Muqit,Carlos Pavesio,Hayley Boston et al.
Mahiul Muhammed Khan Muqit et al.
Postoperative bacterial endophthalmitis is an infection of the eye's internal tissues resulting from an intraocular procedure. The condition is uncommon but can cause severe and irreversible impairment of sight. Standard management involves...
Zoe Trinder-Widdess,James Nobles,Clare Thomas et al.
Zoe Trinder-Widdess et al.
Stories can be a powerful method of exploring complexity, and the factors affecting everyday physical activity within a modern urban setting are nothing if not complex. The first part of our How Do You Move? study focused on the communicati...
Deprivation, essential and non-essential activities and SARS-CoV-2 infection following the lifting of national public health restrictions in England and Wales [0.03%]
英格兰和威尔士解除全国公共卫生限制后的人群剥夺感、必要及非必要活动与感染SARS-CoV-2的关系
Susan Hoskins,Sarah Beale,Vincent Nguyen et al.
Susan Hoskins et al.
Background: Individuals living in deprived areas in England and Wales undertook essential activities more frequently and experienced higher rates of SARS-CoV-2 infection than less deprived communities during periods of re...