CHI3L1 (YKL-40) and Chit-1 expressing glia in the white matter of ALS, FTLD and AD: correlations to pathology and disease duration [0.03%]
ALS、FTLD和AD的白质中表达CHI3L1（YKL-40）和Chit-1的胶质细胞与病理变化及病程的相关性研究
Chelsea Mauri Tran,Nisha Reddy,J K Thomas et al.
Chelsea Mauri Tran et al.
Background: Chitotriosidase (Chit-1) and chitinase-3-like protein 1 (CHI3L1) protein levels are increased in the cerebrospinal fluid (CSF) of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), fron...
Deep brain stimulation for the treatment of paediatric dystonia due to neuroanatomical abnormalities: a systematic review of efficacy and future perspectives [0.03%]
深层脑刺激治疗神经解剖异常所致儿童肌张力障碍的疗效及未来前景系统评价
Yasmin Soliman,Abbey Figliomeni,Hyunchul Lee et al.
Yasmin Soliman et al.
Background: Paediatric dystonia due to neuroanatomical brain abnormalities causes significant morbidity in affected children. Medical treatments have limited efficacy and deep brain stimulation (DBS) surgery is a potentia...
Large language models to infer depression in patients with neurological conditions [0.03%]
大型语言模型在神经疾病患者抑郁情绪推断中的应用
Maya Julian-Kwong,Shane Poole,Kyra Henderson et al.
Maya Julian-Kwong et al.
Objective: To develop and validate a large language model (LLM) prompt capable of ascertaining a patient's depression from their multiple sclerosis (MS) neurologist's note and to explore its potential for earlier detectio...
MOGAD optic neuritis post enterovirus meningitis: a new association [0.03%]
肠病毒脑膜炎后的视神经炎(MOGAD):一个新的组合病症
Salman Aljarallah,Othman O Aldraihem,Khalid Alqarni
Salman Aljarallah
Introduction: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) is a rare autoimmune demyelinating disorder of the central nervous system, typically presenting with optic neuritis, transverse myeliti...
Foreign body-type giant cell reaction post intracranial endovascular clot retrieval: a postmortem case [0.03%]
颅内血管内取栓术后的异物型巨细胞反应：一例尸检病例
Kanila Perera,Nadya Lazareva,Catriona McLean et al.
Kanila Perera et al.
Background and aims: Endovascular clot retrieval (ECR) has revolutionised acute ischaemic stroke management. While procedural safety is well established, little attention has been paid to vascular responses to hydrophilic...
Arabic version of the General Sleep Disturbance Scale among healthcare night-shift workers: a cross-sectional validation study [0.03%]
医疗夜班工作人员的阿拉伯版本综合睡眠障碍量表：横断面验证性研究
Wesam Osama,Rehab Magdy,Azza Elashiry et al.
Wesam Osama et al.
Background and objectives: The General Sleep Disturbance Scale (GSDS) has been translated and amended into various languages with adequate psychometric properties. However, the Arabic version has not been validated before...
Head trauma and environment progression of amyotrophic lateral sclerosis: long-term data from the National ALS Registry [0.03%]
基于全国ALS登记处的长期数据对头部创伤和渐冻人症发展的环境因素进行的研究
Alfonso Enrique Martinez-Nunez,Jingchuan Guo,Earl Ray Dorsey et al.
Alfonso Enrique Martinez-Nunez et al.
Background: Environmental exposures have been linked to increased risk of amyotrophic lateral sclerosis (ALS); however, their impact on disease progression remains unclear. This study examined whether prior environmental ...
Associations of chrononutrition and sleep with fatigue in multiple sclerosis: an analysis of the Swiss Multiple Sclerosis Registry [0.03%]
慢性营养和睡眠与多发性硬化症患者疲劳的关系：来自瑞士多发性硬化症登记处的分析研究
Nicholas E Phillips,Vladeta Ajdacic-Gross,Jessica Rebeaud et al.
Nicholas E Phillips et al.
Background: Fatigue is a common symptom of multiple sclerosis (MS) and impacts quality of life, yet the role of chrononutrition and sleep in MS management remains underexplored. We aimed to investigate the cross-sectional...
A mixed-methods study of patient perspectives on antiseizure medication discontinuation attempts after a period of seizure-freedom [0.03%]
一项关于癫痫发作间期减停抗癫痫药物尝试的患者视角的混合研究方法研究
Samuel W Terman,Jordan M Silva,Max Kuster et al.
Samuel W Terman et al.
Background: Antiseizure medications (ASMs) are the standard treatment for epilepsy. Yet because ASMs can have adverse effects and seizure risk decreases with longer seizure-free periods, guidelines have suggested consider...
Impact of X-linked dystonia-parkinsonism on caregiver strain, anxiety and depression [0.03%]
X染色体显性遗传性扭转痉挛-帕金森病对照料者负担、焦虑和抑郁的影响
Paulo Cataniag,Jed Noel Ong,Cid Czarina Diesta
Paulo Cataniag
Background: X-linked dystonia-parkinsonism (XDP) is a progressive movement disorder that predominantly affects men from the Panay Islands in the Philippines. Although patient outcomes have been well described, the effect ...