Considering prediagnostic environmental modifiers of progression in amyotrophic lateral sclerosis [0.03%]
考虑环境因素在肌萎缩侧索硬化病前阶段进展中的作用
Christos V Chalitsios,Martin R Turner
Christos V Chalitsios
Nationwide analysis of real-world access to and use of device-aided therapies in Parkinson's disease: insights from the French National Healthcare Data System (2015-2021) [0.03%]
基于法国国家卫生信息系统(2015-2021年)的全国分析：帕金森病患者辅助治疗的实际可及性和使用情况启示
Manon Auffret,Emmanuel Nowak,Marc Vérin et al.
Manon Auffret et al.
Background and objectives: Device-aided therapies (DAT) have significantly improved the management of Parkinson's disease (PD). They now include deep brain stimulation (DBS), levodopa-carbidopa intestinal gel (LCIG) infus...
Health inequalities in outpatient neurological conditions across a large UK urban population: a retrospective observational study using automated coding [0.03%]
英国大城市居民门诊神经疾病的健康不平等性研究——一项基于自动化编码的大样本回顾性观察研究
Keira Markey,Robyn Hamilton,Rohan Ahmed et al.
Keira Markey et al.
Objectives: To use automated coding to identify broad neurological diagnoses and link to sociodemographic data. Design: Retrospective o...
Slowing the curve: a single-arm meta-analysis of mFARS outcomes following omaveloxolone treatment in Friedreich ataxia [0.03%]
降斜研究：Omaveloxolone治疗Friedreich共济失调症的单臂meta分析效果研究
Aasim Ali,Waqar Ahmed Cheema,Fiza Nisar et al.
Aasim Ali et al.
Friedreich ataxia (FRDA) is a progressive neurodegenerative disorder with limited treatments. Omaveloxolone, an Nrf2 activator, was approved based on a phase III trial showing modified Friedreich Ataxia Rating Scale (mFARS) improvement. Rea...
6-minute walk test and the 3-metre backward walk test are sensitive to postoperative gait improvement in idiopathic normal pressure hydrocephalus [0.03%]
六分钟步行试验和三米后退步行试验可反映特发性正常压力脑积水术后步态改善状况
Johanna Andersson,Lena Kollen,Hanna C Persson et al.
Johanna Andersson et al.
Background: Gait impairment is a core symptom in idiopathic normal pressure hydrocephalus (iNPH), but commonly used tests like the 10-metre walk test (10MWT) may underestimate postoperative improvements. We evaluated the ...
Anticoagulation associated intracerebral haemorrhage trends, treatment and outcomes in a metropolitan cohort: analysed by availability of specific versus non-specific reversal agents [0.03%]
特定和非特异性逆转剂可获得性影响下的抗凝相关脑内出血的地域趋势、治疗及结局分析
Shaddy El-Masri,Rudy Goh,Stephen Bacchi et al.
Shaddy El-Masri et al.
Background: Direct oral anticoagulants (rivaroxaban, apixaban, dabigatran) and warfarin treatment are associated with an increased risk of intracerebral haemorrhage (ICH). Specific reversal exists for warfarin (vitamin K/...
Efficacy of nebulised dexmedetomidine versus aminophylline for treatment of postdural puncture headache in patients undergoing subarachnoid block posted for caesarean section: a double-blind, randomised controlled study [0.03%]
用于剖宫产腰麻患者术后硬膜穿刺后头痛治疗的右美托咪定与氨茶碱雾化疗效比较：一项双盲随机对照研究
R K V Kavya,Neeraj Kumar,Abhyuday Kumar et al.
R K V Kavya et al.
Background: Postdural puncture headache (PDPH) following spinal anaesthesia significantly affects postpartum recovery. We evaluated the efficacy of nebulised dexmedetomidine and aminophylline in women with moderate to sev...
Correlation of cerebrospinal fluid IL-6 as a marker of disease activity in patients with longitudinally extensive transverse myelitis [0.03%]
脑脊液中的IL-6作为长段性横贯性脊髓炎的疾病活动标志物的相关性研究
Sangam Singh,Ajai Kumar Singh,Pradeep Kumar Maurya et al.
Sangam Singh et al.
Background: Longitudinally extensive transverse myelitis (LETM) is a severe inflammatory spinal cord disorder. It is commonly associated with neuromyelitis optica spectrum disorders and other autoimmune conditions like Sj...
Blood pressure variation and futile recanalisation in patients with large-vessel occlusion after endovascular therapy [0.03%]
血管内治疗后大型血管闭塞患者的血压波动与无效再通关系研究
Tieying Cai,Jiandi Huang,Shuang Yang et al.
Tieying Cai et al.
Background and purpose: Although systolic blood pressure variation (ΔSBP) has been regarded as a predictor of poor outcome after endovascular therapy (EVT), its effect at the different time intervals on the prognosis of ...
Pablo Gómez-Porro,Beatriz De La Puente,Lorena Fernández et al.
Pablo Gómez-Porro et al.
Background: Inflammatory cerebral amyloid angiopathy (ICAA) is an atypical presentation of cerebral amyloid angiopathy (CAA), caused by an autoimmune reaction against cerebral beta-amyloid deposits. ICAA can be divided in...