Bi-allelic intermediate ATXN2 repeat expansions are associated with slow progressing, leg-onset familial ALS [0.03%]
双等位基因中间ATXN2重复扩增与缓慢进展的家族性ALS下肢发病有关
Koen Cedric Demaegd,Wouter Koole,Joke Jfa van Vugt et al.
Koen Cedric Demaegd et al.
Objectives: The identification of bi-allelic intermediate ATXN2 repeat expansions in a pedigree with amyotrophic lateral sclerosis (ALS) through clinical testing prompted us to investigate its relevance in the wider ALS p...
What is refractory CIDP? [0.03%]
难治性CIDP是什么？
Aisling Carr,Michael P Lunn
Aisling Carr
Parkinson's disease care in Pakistan: overcoming challenges in low- and middle-income countries [0.03%]
巴基斯坦的帕金森病照护：低收入和中等收入国家面临的挑战及应对措施
Sajid Hameed,Renzo Figari-Jordan
Sajid Hameed
Impact of whole-body vibration training on gait in patients with progressive multiple sclerosis: a pilot randomised study [0.03%]
全身振动训练对进展型多发性硬化患者步行影响的初步随机研究
Agni Maria Konitsioti,Yasemin Göreci,Martin Hellmich et al.
Agni Maria Konitsioti et al.
Background: Oscillatory whole-body vibration (WBV) training improves strength and movement skills in healthy adults and individuals with various medical conditions. Studies examining the effects of WBV on gait disorder in...
Reduced intracortical inhibition and enhanced intracortical facilitation in patients with functional tremor [0.03%]
功能性震颤患者的皮层抑制降低和皮层易化增强
Juan Li,Jia Zhao,Yuewen Li et al.
Juan Li et al.
Background: The pathophysiological mechanism underlying functional tremor (FT) has not been elucidated. Transcranial magnetic stimulation (TMS) is a non-invasive tool to explore cortical excitability in various neurologic...
Non-invasive electrodiagnostic testing for small fibre neuropathy in long COVID-19 [0.03%]
长新冠的小纤维神经病的无创电诊断检测
Anthony Khoo,Kisani Manuel,Tracy Ng et al.
Anthony Khoo et al.
Background: Long COVID-19 is associated with a diverse range of debilitating neuropathic and autonomic symptoms that may indicate small fibre neuropathy (SFN). We aimed to assess the utility of multimodal non-invasive ele...
18F-DPA-714 PET/MRI reveals early and widespread neuroinflammation in sporadic Creutzfeldt-Jakob disease: a case report [0.03%]
以多发性克雅病为例的散发性克雅病早期广泛神经炎症的氟-18-DPA-714正电子发射断层磁共振成像表现：病例报告
Zhuoying Zhu,Qing Huang,Sheng Chen et al.
Zhuoying Zhu et al.
Background: Creutzfeldt-Jakob disease (CJD) is a fatal neurodegenerative disorder caused by prion proteins, with microglial activation being a key immunopathological feature. This case report demonstrates the application ...
Seizure burden and treatment efficacy evaluation in anti-LGI1 autoimmune encephalitis patients using wearable device: a pilot feasibility study [0.03%]
使用可穿戴设备评估抗LGI1抗体脑炎患者发作负荷及治疗效应的可行性研究
Jie Cui,Andrea Duque-Lopez,Gabriella Brinkmann et al.
Jie Cui et al.
Background: Patients with anti-leucine-rich glioma-inactivated 1 (anti-LGI1) autoimmune encephalitis (AIE) frequently present with faciobrachial dystonic seizures (FBDS), which are often under-detected due to their subtle...
Exploring cardiac autonomic dysfunction in synucleinopathies with parkinsonism through awake-sleep stages: a possible connection to cardiovascular death [0.03%]
通过觉醒-睡眠周期阶段探讨帕金森综合征原纤维tau蛋白病患者自主神经功能障碍的可能与心血管死亡相关的联系
Natlada Limotai,Thapanee Somboon,Narupat Suanprasert et al.
Natlada Limotai et al.
Introduction: Alpha-synucleinopathies (ASs), including Parkinson's disease, multiple system atrophy and dementia with Lewy bodies, are characterised by autonomic dysfunction that may predispose to cardiovascular events an...
Deep brain stimulation for Parkinson's disease in Thailand: cost, utility and policy implications for universal health coverage [0.03%]
泰国的帕金森病的深部脑刺激：成本、效用及普及医疗政策含义
Saharat Aungsumart,Atittan Songpattanasilp,Surachet Rujirussawarawong et al.
Saharat Aungsumart et al.
Background: Parkinson's disease (PD) is a chronic, progressive, disabling neurodegenerative disorder. Deep brain stimulation (DBS) surgery is a highly effective and beneficial therapy for advanced PD, but its substantial ...