Neurological complications induced by checkpoint inhibitors: characterising the clinical spectra [0.03%]
检查点抑制剂引起的神经系统并发症：阐明临床谱系特征
Anne Merel van Wylick,Martin van den Bent,Bart C Jacobs et al.
Anne Merel van Wylick et al.
Background: Timely recognition of immune checkpoint immune-related neurological adverse events (irNAEs) is critical given their potential severity, yet remains challenging due to limited clinical experience. This study in...
Clinicians' decisions about antibiotic treatment in advanced dementia: an international survey [0.03%]
关于晚期痴呆症抗生素治疗的临床决策：一项国际调查
João Pedro Lima,Lawrence Mbuagbaw,Manya Prasad et al.
João Pedro Lima et al.
Objectives: In patients living with advanced dementia, the intensity of care during life-threatening infections remains controversial and marked by wide variation in practice. This international survey investigated physic...
Stroke risk in patients with hypertensive retinopathy: a systematic review and meta-analysis [0.03%]
糖尿病视网膜病变患者的卒中风险：系统回顾和荟萃分析
Jing Zhang,Xiaorong Zhang,Yong Liu et al.
Jing Zhang et al.
Background: Hypertensive retinopathy (HTRP) is a complication of hypertension and is recognised as hypertension-mediated target-organ damage. Hypertension is also the leading risk factor for stroke. This systematic review...
Expanding the clinical phenotype associated with an ASXL1 pathogenic variant causing a novel neuromuscular disorder with neurodevelopmental features [0.03%]
ASXL1致病性变异相关的临床表型扩展导致一种具有神经发育特征的新型神经肌肉障碍
Dominic Spicer,Kathryn Friend,Bing Wu et al.
Dominic Spicer et al.
Background: Germline pathogenic variants in the Additional Sex Combs-Like 1 (ASXL1) gene are associated with the neurodevelopmental Bohring-Opitz syndrome and cancers like Wilms' tumours. Bohring-Opitz syndrome is a pheno...
Rising burden of Alzheimer's disease and other dementias in Sierra Leone, 1990-2023: analysis of Global Burden of Disease 2023 estimates [0.03%]
1990-2023年塞拉利昂阿尔茨海默病和其他痴呆症负担加重：分析全球疾病负担2023估计数据
Mohamed B Jalloh,Gibrilla Fadlu Deen,Omar Bah et al.
Mohamed B Jalloh et al.
Background: Dementia is an increasing cause of disability and mortality worldwide. Primary dementia surveillance data remain limited in many low-income settings, including Sierra Leone. ...
Case of Aicardi-Goutières syndrome diagnosed in adulthood on whole-genome sequencing [0.03%]
成人Aicardi-Goutières综合征的全基因组测序诊断病例
Lewis Cobb,Jayant Kumar,Amit Roy et al.
Lewis Cobb et al.
Background: Aicardi-Goutières syndrome (AGS) is a neurogenetic leukoencephalopathy that typically manifests within the first 6 months of life. Classically, AGS presents with an early encephalopathic episode characterised by feeding difficu...
Siyu Chen,Tianrui Yu,Yuanyuan Xiang et al.
Siyu Chen et al.
Moyamoya disease (MMD) is a rare cerebrovascular disease characterised by gradual progressive stenosis and occlusion of the terminal internal carotid arteries, anterior cerebral arteries and proximal middle cerebral arteries bilaterally. Th...
Deep brain stimulation battery longevity: a cohort study comparing impact of anaesthesia modality and anatomic target [0.03%]
深部脑刺激电池耐久性：麻醉模式和解剖靶点对电池寿命影响的队列研究
Noor Zaghlula,Kelsey Kinsman,Oliver Phillips et al.
Noor Zaghlula et al.
Background: Deep brain stimulation (DBS) treats various movement disorders, though routine battery replacement is required. Factors affecting battery life remain unclear; prior studies implicate programming parameters and...
Smoking and the risk of neurodegenerative diseases in a Chinese case-control study [0.03%]
中国队列研究中吸烟与神经退行性疾病风险的关系
Jia Nie,Susan Peters,Calvin B Ge et al.
Jia Nie et al.
Background: While smoking is inversely associated with Parkinson's disease (PD) risk, its relationship with amyotrophic lateral sclerosis (ALS) and multiple system atrophy (MSA) remains unclear, particularly in Asian popu...
Non-invasive brain stimulation for enhancing dual-task performance in individuals with chronic poststroke hemiparesis: protocol for systematic review and meta-analysis [0.03%]
慢性卒中后偏瘫个体双任务表现的非侵入性脑刺激增强系统综述和meta分析方案
Greco Adan Neblina,Katie Alexandra Schloss,Arliz Serrano Herrera et al.
Greco Adan Neblina et al.
Introduction: Dual-tasking is commonly used to assess functional capacity in neurologically intact and poststroke populations. Stroke survivors often experience significant dual-task deficits due to cognitive-motor interf...