Phytochemical Analysis and Compound Profiling of Boerhavia elegans Stem Extract Using GC-MS [0.03%]
利用GC-MS进行对美化旋花茎提取物的植化分析和化合物谱分析
Tahreer M Al-Raddadi,Saleh O Bahaffi,Lateefa A Alk-Hateeb
Tahreer M Al-Raddadi
Natural products are essential in drug discovery and have diverse applications in biotechnology. Naturally derived compounds are widely recognized as lead candidates in conventional drug development. Molecular docking has become a valuable ...
Advancements in Ambient Ionisation Mass Spectrometry in 2024: An Annual Review [0.03%]
2024年环境离子化质谱技术的进展：年度回顾
Alisha Henderson,Liam M Heaney,Stephanie Rankin-Turner
Alisha Henderson
The introduction of ambient ionisation mass spectrometry (AIMS) is among the most important developments in analytical chemistry in recent years. Enabling the direct analysis of samples in their native state with neither sample preparation ...
In-Tip Nanoreactors for Simultaneous Proteolysis and Enrichment of Phosphorylated Peptides [0.03%]
用于蛋白质水解和磷酸化肽富集的纳米反应器
Ling Yan
Ling Yan
Protein phosphorylation introduces negative charges on the hydroxyl groups of serine, threonine, and tyrosine residues, reducing the ionization efficiency of phosphorylated peptides. The low abundance of phosphorylated peptides often dimini...
Chemometric Model for Rapid Determination of Syringyl/Guaiacyl Ratio in Non-Wood by FT-NIR Spectroscopic Data [0.03%]
非木本植物中愈疮木基/紫丁香基比率的快速测定的化学计量学模型
M Nashir Uddin,Taslima Ferdous,Yangcan Jin et al.
M Nashir Uddin et al.
The present study is to develop a cost-effective, non-destructive and rapid method for quantification of syringyl/guaiacyl (S/G) ratio content in non-wood lignin, which is based on FT-NIR spectroscopic data and chemometric modelling techniq...
A new methodology for sub-femtomolar detection of organic molecules through the combination of surface-enhanced Raman spectroscopy and a superhydrophobic fluidic concentrator [0.03%]
通过结合超疏水流体浓缩器和表面增强拉曼光谱实现皮摩尔有机分子检测的新方法论
Victor Fabre,Franck Carcenac,Adrian Laborde et al.
Victor Fabre et al.
A specific device that combines (1) surface-enhanced Raman spectroscopy (SERS) and (2) superhydrophobic surfaces is developed to detect traces of analytes diluted at sub-femtomolar concentration in water solutions. The first step of the ana...
Simultaneous Determination of Residual Contamination of Eight Antineoplastic on Surfaces by HILIC Chromatography Coupled to High-Resolution Spectrometry [0.03%]
HILIC色谱耦合高分辨率光谱法同时测定表面八种抗肿瘤药物残留污染
Zribi Kaouther,Sarra Berriri,Danielle Libong et al.
Zribi Kaouther et al.
Residual contamination by intravenous antineoplastic drugs on hospital surfaces remains a critical concern, as highlighted by numerous studies. This study presents a novel, rapid and highly sensitive analytical method for quantifying a wide...
Exploring of Antidepressant Components and Mechanisms of Zhizichi Decoction: Integration of Serum Pharmacochemistry, Network Pharmacology and Anti-inflammatory Analysis Verification [0.03%]
滋肾益气汤抗抑郁成分及机制探索：血清药物化学结合网络药理学和抗炎分析验证研究
Chuan Chai,Bo Jin,Jinghan Bi et al.
Chuan Chai et al.
Using LC-MS to screen and analyse the characteristics of components and biological systems is a new approach to study the pharmacological substance basis of traditional Chinese medicine, which has strong novelty in analytical science. This ...
A Dual Biomarker Approach to Stress: Hair and Salivary Cortisol Measurement in Students via LC-MS/MS [0.03%]
应激的双生物标志物方法：通过LC-MS / MS在学生中的毛发和唾液皮质醇测量
Muhammad K Hakeem,Sundas Sallabi,Raghda Ahmed et al.
Muhammad K Hakeem et al.
Stress is a significant issue among students, affecting both their mental and physical health. In this study, we investigated cortisol levels, a key biomarker for stress, in students at the United Arab Emirates University (UAEU) during thei...
Cost-Effective Nanosensor Solutions for Ultra-Sensitive Detection of Metronidazole [0.03%]
用于超灵敏检测甲硝唑的成本效益纳米传感器解决方案
Ahmad Mobed,Mohammad Darvishi,Vahid Alivirdiloo et al.
Ahmad Mobed et al.
Metronidazole (MNZ) is a widely used imidazole antibiotic effective against bacterial and protozoal infections, including giardiasis, trichomoniasis, bacterial vaginosis, and antibiotic-associated colitis. However, prolonged and excessive u...
Incremental Modification in the Existing Approaches for Affinity Chromatographic Enrichment of Phosphoproteins Improves Their Profile in Liquid Chromatography-Tandem Mass Spectrometry Analysis [0.03%]
改进亲和色谱富集磷酸化蛋白质的方法可改善其在液相色谱-串联质谱分析中的图谱
Neha Agrawal,Rukmini Govekar
Neha Agrawal
Cell signalling is a vital process in cell physiology, which is driven by protein phosphorylation. Global phosphoproteome analysis by liquid chromatography-tandem mass spectrometry (LC-MS/MS) has thus gained importance in cell signalling re...