Beyond Beer-Lambert Linear Regression: Multi-Layer Modeling for Wide-Range Concentration Quantification Using Ultraviolet-visible Spectroscopy [0.03%]
超越比尔朗伯线性回归:使用紫外可见光谱法广泛浓度定量的多层建模方法
Muhammed ALjifri,Carter Miller,Yanjun Qian et al.
Muhammed ALjifri et al.
Ultraviolet-visible (UV-Vis) spectroscopy is widely used for chemical quantification due to its simplicity and low cost; however, accurate concentration prediction becomes challenging when target concentrations span wide ranges, where the g...
A Novel Ultra-Performance Liquid Chromatography-Electrospray Ionisation-Tandem Mass Spectrometry Method for Quantification of Imeglimin in Human Plasma: Application to a Bioequivalence Study [0.03%]
一种新颖的超性能液相色谱-电喷雾串联质谱法定量测定人血浆中伊格列净的方法:在生物等效性研究中的应用
Mina Wadie,Kamal A Badr,Ahmed A Hosny et al.
Mina Wadie et al.
The pharmaceutical market has recently witnessed the advent of a novel tetrahydrotriazene molecule belonging to the new pharmacological class "Glimins", named Imeglimin (IMG). It has been approved in Japan as a safe and highly effective ora...
Method Comparison of Dried Blood Spot and Plasma Apolipoprotein B Measurement on a Semi-Automated Analyser: Toward Accessible Lipid Profiling in Resource-Limited Settings [0.03%]
在资源有限地区进行血脂谱分析的可行性:基于半自动分析仪的干血点和血浆载脂蛋白B测定方法学对比研究
Bronwyn Pitampersad,Savathree Madurai,Bhavani Manivannan et al.
Bronwyn Pitampersad et al.
Apolipoprotein B (ApoB) is a key marker of atherogenic lipoprotein burden, but conventional plasma-based testing requires venous sampling and centralized laboratory infrastructure. Dried blood spot (DBS) sampling offers a minimally invasive...
Metabolomic Differentiation of Malpighiaceae From Dry and Humid Tropics via UHPLC-MS/MS and Chemometrics [0.03%]
基于UHPLC-MS/MS和化学计量学的干燥和潮湿热带地区马拉皮亚科属植物代谢组差异分析
Jaqueline Munise Guimarães da Silva,Rafael Felipe de Almeida,Maria Luiza Zeraik
Jaqueline Munise Guimarães da Silva
Various factors can trigger water stress in plants, particularly in those growing in dry tropical regions. To survive under such conditions, plants produce metabolites with adaptive functions. However, metabolomic data on the leaves of Malp...
A New Kinetic-Mechanistic Approach Towards Spectrophotometric Bioanalysis of 2-Phenylethylamine as a Sympathomimetic Agent Using Sodium Isopropyl Xanthate [0.03%]
一种新的动力学-机制光谱法生物分析肾上腺素受体激动剂2-苯乙胺的方法及使用 sodium isopropyl xanthate 进行测定
Fatemeh Nami,Houman Kholafazad,Mohammad Hasanzadeh et al.
Fatemeh Nami et al.
2-Phenylethylamine (2-PEA), an aromatic biogenic amine, demonstrates significant physiological and toxicological effects on human health. A variety of conventional methods have been widely used for the determination of 2-PEA. However, the n...
Stacked Ensemble Model With Explainable AI for Early Detection of Heart Disease [0.03%]
基于可解释AI的早期心脏病检测栈式集成模型
Nazmun Nahar,Sanjatul Hasan Siam,Joy Bhowmik et al.
Nazmun Nahar et al.
Heart disease (HD) is still one of the most common causes of death around the world. Early detection is very important, but it is often hard to do because the symptoms are not specific and the models are not very clear. We propose a two-lay...
Monitoring of Metabolic Disorders Through Electro-Sensing of Riboflavin by Novel Super-Conductive Silver Ink Modified Paper [0.03%]
基于新型超导性银墨的纸基电化学传感监测富勒烯素代谢异常研究
Rokhsareh Ebrahimi,Mohammad Hasanzadeh,Nasrin Shadjou
Rokhsareh Ebrahimi
Riboflavin (RIB), or vitamin B2, plays a key role in cellular protection against oxidative stress, and its deficiency can cause severe physiological complications, including metabolic disorders, photosensitivity, anaemia, growth delay and g...
Atom-by-Atom Multimetal CuMoP Deposition on Carbon Electrodes for Sensitive Antidiabetic Metformin Electrooxidation [0.03%]
原子级多金属CuMoP催化剂电极的制备及其在提高降糖药甲福明安电氧化灵敏度方面的应用研究
Hong Wan,Mingfang Zhan,Chunyan Yin et al.
Hong Wan et al.
An atom-by-atom ternary Cu-Mo-P nanocomposite was electrochemically co-deposited onto screen-printed carbon electrodes (SPCEs) to form a highly active sensing interface for the determination of metformin (MF). The one-step anodic fabricatio...
Advances in Eco-Friendly Extraction of Fruit Bioactive Compounds: Technologies, Challenges and Future Directions [0.03%]
绿色果蔬活性成分提取技术及其面临的挑战与未来发展趋势
Abadi Gebreyesus Hndeya,Desta Berhe Sbhatu,Gebreselema Gebreyohannes
Abadi Gebreyesus Hndeya
Fruit bioactive compounds such as polyphenols, carotenoids, vitamins and fibres provide important antioxidant, anti-inflammatory and disease-preventive benefits, but their extraction remains difficult due to poor solubility and the limitati...
Stimuli-Responsive Crosslinked Chitosan/PVP/PEG Hydrogel Networks for Targeted Drug Delivery and Antimicrobial Performance [0.03%]
刺激响应型交联壳聚糖/PVP/PEG水凝胶网络在药物递送和抗菌性能方面的应用
Danial Mazhar,Sumra Afzal,Safia Hassan et al.
Danial Mazhar et al.
In this study, a unique pH-sensitive PEG/C/PVA hydrogel based on chitosan (C), polyvinyl propylene (PVP) and polyethylenglycol (PEG) crosslinked with tetraethyl orthosilicate (TEOS) was fabricated. This PEG/C/PVA hydrogel was designed to de...