Analytical considerations for accurately capturing the relevant species contributing to vitamin D status in liquid chromatography-tandem mass spectrometry assays [0.03%]
液相色谱-串联质谱测定维生素D营养状况相关种属时应注意的问题分析
Dietrich A Volmer,Caroline S Stokes
Dietrich A Volmer
This tutorial review focuses on analytical challenges encountered with the liquid chromatography-tandem mass spectrometry determination of 25-hydroxyvitamin D, which is currently still considered the metabolite that is most representative o...
Probing for the presence of semenogelin in human urine by immunological and chromatographic-mass spectrometric methods in the context of sports drug testing [0.03%]
免疫和色谱-质谱法测定人尿中精液素以辅助运动禁用药物检测研究
Johanna Breuer,Andreas Thomas,Hans Geyer et al.
Johanna Breuer et al.
Rationale: An increasing number of adverse analytical findings (AAFs) in routine doping controls has been suspected and debated to presumably result from intimate contact with bodily fluids (including ejaculate), potentia...
Quantitative age grading of mosquitoes using surface-enhanced Raman spectroscopy [0.03%]
基于表面增强拉曼光谱的蚊虫定量年龄鉴定
Danhui Wang,Jason Yang,Janam Pandya et al.
Danhui Wang et al.
Mosquito-borne pathogens, including malaria, Zika, dengue, and chikungunya continue to be a major public health concern globally. Based on the understanding that only older female mosquitoes are infectious and represent a risk to human heal...
Analysis of the isomerization of diketopiperazine consisting of proline and aromatic amino acid residues using nuclear magnetic resonance [0.03%]
核磁共振法分析由脯氨酸和芳香族氨基酸残基组成的二酮哌嗪的异构化分析
Takashi Ishizu,Popuri Sato,Shiori Tsuyama et al.
Takashi Ishizu et al.
Under different concentrations of the base potassium deuteroxide KOD, the progress of reactions, such as enolization, D-substitution, isomerization, and conformational changes of diketopiperazine cyclo(L-Pro-L-Xxx) and cyclo(D-Pro-L-Xxx) (X...
Task-adaptive eigenvector-based projection (EBP) transform for compressed sensing: A case study of spectroscopic profiling sensor [0.03%]
基于任务自适应特征向量的压缩感知投影（EBP）变换：以光谱检测为例的研究
Yinsheng Zhang,Haiyan Wang,Yongbo Cheng et al.
Yinsheng Zhang et al.
The compressed sensing (CS) theory requires the signal to be sparse under some transform. For most signals (e.g., speech and photos), the non-adaptive transform bases, such as discrete cosine transform (DCT), discrete Fourier transform (DFT...
Profiling acidic metabolites by capillary electrophoresis-mass spectrometry in low numbers of mammalian cells using a novel chemical derivatization approach [0.03%]
利用新型化学衍生方法通过毛细管电泳-质谱技术对少量哺乳动物细胞中的酸性代谢物进行分析
Marlien van Mever,Cornelius C W Willacey,Wei Zhang et al.
Marlien van Mever et al.
The simultaneous analysis of a broad range of polar ionogenic metabolites using capillary electrophoresis-mass spectrometry (CE-MS) can be challenging, as two different analytical methods are often required, that is, one for cations and one...
Isolation, separation, identification, and quantification of bioactive methylated flavone regioisomers by UHPLC-MS/MS [0.03%]
超高效液相色谱-串联质谱法分离、鉴定和定量活性甲基化黄酮区域异构体
Hafiza Noreen,Edward N Smith,Muhammad Farman et al.
Hafiza Noreen et al.
Methylated flavones, commonly found in many plants of the Brassicaceae family, have potent antioxidant and anticancer activity with diverse therapeutic potential. However, the specific regioisomers of methylated flavones can have significan...
Development of a multiclass method to quantify phthalates, pharmaceuticals, and personal care products in river water using ultra-high performance liquid chromatography coupled with quadrupole hybrid Orbitrap mass spectrometry [0.03%]
基于超高液相色谱-四极杆复合型轨道阱质谱的河流水中增塑剂、药物及个人护理产品多组分定量方法研究
Deviprasad Rendedula,Gubbala Naga Venkata Satyanarayana,Ankita Asati et al.
Deviprasad Rendedula et al.
Rationale: The organic micropollutants such as phthalates, pharmaceuticals, and personal care products (PPPCPs) enter the surface water through various routes. The aim of this study is to develop a sensitive and efficient...
Evaluation of micropillar array columns for chromatographic separation of phosphorothioated oligonucleotides and their diastereomers [0.03%]
微柱阵列色谱柱用于手性硫代磷酸核酸和它的非对映异构体分离性能的评估
Lieve Dillen,Tiny Deschrijver,Kurt Van Mol et al.
Lieve Dillen et al.
Chromatographic analysis of therapeutic oligonucleotides is challenging due to the presence of closely related impurities, degradants or metabolites and due to the presence of phosphorothioate bonds, which introduce chiral centers. In the p...
Highly sensitive and repeatable DNA-SERS detection system using silver nanowires-glass fiber filter substrate [0.03%]
一种基于银纳米线-玻璃滤光片基底的DNA-SERS高灵敏可重复检测系统
Ayoung Woo,Kyongmook Lim,Baek Hwan Cho et al.
Ayoung Woo et al.
This paper describes a new simple DNA detection method based on surface-enhanced Raman scattering (SERS) technology using a silver nanowire stacked-glass fiber filter substrate. In this system, DNA-intercalating dye (EVAGreen) and reference...