Analysis of Two New Flavonoid Glycosides From Zanha golungensis Hiern With COX Inhibition Activity: Structural Elucidation, DFT Calculations, In Vitro and Molecular Docking Assessment [0.03%]
基于cox抑制活性从扎那氏高尔龙根中分离两种新的黄酮类糖苷的分析：结构确证，dft计算及体外和分子对接评估
Jean Zeuikena,Romeo Toko Feunaing,Alfred Ngenge Tamfu et al.
Jean Zeuikena et al.
Zanha golungensis is used as herbal medicine for a variety of ailments. In this study, flavonoids, including two new kaempferide polyglycosides, namely, kaempferide-3-O-[α-l-rhamnopyranosyl-(1 → 2 )-α-l-rhamnopyranosyl-(1 →...
A Selective Phenyl Azo Acetate Substrate for Enhanced Carbonic Anhydrase Functional Analysis [0.03%]
一种苯偶氮乙酸盐底物用于增强碳酸酐酶的功能分析
Justinas Babinskas,Inga Matijošytė
Justinas Babinskas
Carbon dioxide (CO2) sequestration is a key strategy for mitigating climate change, and biocatalytic approaches offer sustainable, cost-effective alternatives to chemical and physical methods. Carbonic anhydrases (CAs) efficiently catalyse ...
A Robust Cost-Effective Spectrophotometric Method for Nb Determination in Refractory Nb-doped Gadolinium Zirconate: Overcoming Matrix Dissolution Challenges [0.03%]
一种 robust 和经济的分光光度法测定耐火掺铌钆锆酸盐中的Nb：克服基质溶解难题
Poonam Verma,Annapurna Chandane
Poonam Verma
A simple, robust and cost-effective analytical methodology was developed for the determination of niobium in highly refractory materials: Nb-doped gadolinium zirconate (Gd2Zr2O7:Nb) and niobium pentoxide (Nb2O5). The challenge of digesting ...
PANI/PTA/Fe3O4 Nanocomposite Coated on Stainless-Steel Towards Efficient Solid-Phase Microextraction of Tetracycline From Human Urine Samples Prior to HPLC-DAD Analysis [0.03%]
壳聚糖-多巴胺功能化磁性微球固相微萃取高效提取人尿液中四环素类抗生素
Sanaz Naghinejad Orang,Hossein Salar Amoli,Mohammad Hasanzadeh
Sanaz Naghinejad Orang
Tetracycline (TC) is a commonly prescribed broad-spectrum antibiotic, and its widespread use together with its persistence in biological matrices, particularly urine, has raised serious concerns related to clinical safety, public health and...
Comprehensive Quantitative Urinary Steroid Profiling of 29 Steroids Using Liquid Chromatography-Tandem Mass Spectrometry [0.03%]
采用液相色谱-串联质谱法对尿中29种甾体进行综合定量分析
Joshua T Bain,Fozia Shaheen,Alessandro Prete et al.
Joshua T Bain et al.
Steroids are critical for numerous physiological processes; disruption in their metabolism is associated with numerous endocrine disorders. Steroid quantification is essential to improve the understanding and diagnosis of these pathologies....
Rapid Analysis of Sports Prohibited Substances in Black Market Pharmaceutical Products Using Atmospheric Solids Analysis Probe-Mass Spectrometry [0.03%]
利用大气固相探针-质谱技术对地下市场中非法添加违禁物质的药品进行快速筛查分析
Alisha Henderson,Oliver Krug,Ashley Sage et al.
Alisha Henderson et al.
Misuse of performance-enhancing substances in sport remains a persistent threat to the values of fair competition, with estimated doping prevalence far exceeding adverse analytical findings in routine testing. This highlights the need for i...
Method Development and Validation for the Simultaneous Analysis of Miconazole Nitrate, Hydrocortisone and Chlorocresol in a Pharmaceutical Topical Cream by Reverse Phase Liquid Chromatography [0.03%]
反相液相色谱法同时分析外用软膏中硝酸咪康唑、氢化可的松和氯甲酚的方法学建立与验证
Netai Mukaratirwa-Muchanyereyi,Pretty Chihiya,Stephen Nyoni
Netai Mukaratirwa-Muchanyereyi
Miconazole/Hydrocortisone (HCA) cream is a pharmaceutical formulation developed as a combination of three major components (HCA, miconazole nitrate [MCN] and chlorocresol [CHL]). In some instances, reference monographs used for referencing ...
Dry Deposition Strategies for MALDI-MS Imaging: Principles, Advances and Emerging Applications [0.03%]
基质辅助激光解吸电离质谱成像的干沉积策略：原理、进展及新兴应用
Toufik Mahamdi,Oscar Yanes
Toufik Mahamdi
Matrix-assisted laser desorption/ionisation mass spectrometry imaging (MALDI-MSI) has become a pivotal tool in biomedical research, enabling untargeted, spatially resolved analysis of molecular species in complex biological tissues. Among t...
Extraction of Sulfachloropyridazine from Food Samples Using Cellulose: Application of Central Composite Design Approach [0.03%]
基于中央组合设计的纤维素材料从食品中提取磺胺氯吡嗪钠研究
Mbuyelo Shikweni,Nikita Tawanda Tavengwa,Rabelani Mudzielwana et al.
Mbuyelo Shikweni et al.
Sulfonamide antibiotics are among the most widely used veterinary drugs in livestock and often end up contaminating milk, which is subsequently consumed by humans. To mitigate this health hazard, cellulose and its functionalized derivatives...
Wooden-Tip Electrospray Ionization Mass Spectrometry Combined With Machine Learning for Differentiating Thyroid Tumours [0.03%]
基于木棒电喷雾离子化质谱结合机器学习的甲状腺结节良恶性鉴别诊断方法研究
Da-Sheng Liu,Li Liu,Baixue Wang et al.
Da-Sheng Liu et al.
Direct mass spectrometry (MS) analysis of human tissues at the molecular level has great potential for clinical diagnosis and biomarker discovery. However, conventional MS-based analytical methods often require complicated and time-consumin...