Modelos para estimar la variación biológica y la interpretación de resultados seriados: bondades y limitaciones [0.03%]
用于估计生物变异和解释连续结果的模型：优点和局限性
Jorge Díaz-Garzón,Pilar Fernández-Calle,Carmen Ricós
Jorge Díaz-Garzón
La variación biológica (VB) tiene múltiples aplicaciones en diversos campos del laboratorio clínico. Hay dos formas de relacionar el concepto de VB y los modelos estadísticos. Por un lado existen modelos para el cálculo de estimados d...
Critical appraisal and meta-analysis of biological variation studies on glycosylated albumin, glucose and HbA1c [0.03%]
糖化清蛋白、血糖和糖化血红蛋白生物变异批判性评价及meta分析
Carmen Ricós,Pilar Fernández-Calle,Elisabet Gonzalez-Lao et al.
Carmen Ricós et al.
Objectives: Numerous biological variation (BV) studies have been performed over the years, but the quality of these studies vary. The objectives of this study were to perform a systematic review and critical appraisal of ...
Mulberry bodies in the urine sediment of a patient with chronic kidney disease [0.03%]
慢性肾病患者的尿沉渣中的桑葚体
Carlos Martínez-Figueroa,Karen Cortés-Sarabia,Hilda Guadalupe Catalán-Nájera et al.
Carlos Martínez-Figueroa et al.
Objectives: Fabry disease is a hereditary disease caused by a mutation in the α-galactosidase A (GLA) gene resulting in the accumulation of glycosphingolipids in different organs. Timely diagnosis is crucial for the earl...
Optimization of workflow and screening panels for the detection of malignant monoclonal gammopathies [0.03%]
恶性单克隆免疫球蛋白病检测的工作流程和筛查项目的优化
Raquel Oliveros Conejero,Pilar Pascual Usandizaga,Adolfo Garrido Chércoles
Raquel Oliveros Conejero
Objectives: Multiple myeloma (MM) is one of the hematologic malignancies with a greater delay in diagnosis. Laboratories receive numerous MM screening test requests without a specific suspicion, which entails a substantia...
Models to estimate biological variation components and interpretation of serial results: strengths and limitations [0.03%]
估计生物变异成分及连续结果解释的模型及其优劣点
Jorge Díaz-Garzón Marco,Pilar Fernández-Calle,Carmen Ricós
Jorge Díaz-Garzón Marco
Biological variation (BV) has multiple applications in a variety of fields of clinical laboratory. The use of BV in statistical modeling is twofold. On the one hand, some models are used for the generation of BV estimates (within- and betwe...
Wladimiro Jiménez
Wladimiro Jiménez
Salvador Ventura Pedret,Esther Solé Llop,Josep M Queraltó Compañó et al.
Salvador Ventura Pedret et al.
Salvador Ventura Pedret,Esther Solé Llop,Josep M Queraltó Compañó et al.
Salvador Ventura Pedret et al.
Variación biológica: un aspecto de la medicina de laboratorio aún en desarrollo [0.03%]
生物变异：仍然在发展的实验室医学的一个方面
Callum G Fraser
Callum G Fraser
Liquid biopsy for cancer management: a revolutionary but still limited new tool for precision medicine [0.03%]
液体活检在癌症管理方面的应用：一种革命性的但仍然有限的精准医疗新工具
María Arechederra,Matías A Ávila,Carmen Berasain
María Arechederra
The term liquid biopsy is used in contraposition to the traditional "solid" tissue biopsy. In the oncology field it has opened a new plethora of clinical opportunities as tumor-derived material is shedded into the different biofluids from w...