Xavier Filella
Xavier Filella
The value of the prostate-specific antigen (PSA) in prostate cancer (PCa) screening is controversial. Contradictory results have been reported in the literature as to whether PSA-based screening reduces mortality. Also, some of the studies ...
Impact of implementing a category 1 external quality assurance scheme for monitoring harmonization of clinical laboratories in Spain [0.03%]
西班牙临床实验室检验结果可比性外部质量评估体系CAT-I方案的实施效果分析
Carmen Ricós,Pilar Fernández-Calle,Fernando Marqués et al.
Carmen Ricós et al.
Background: The objective of the present study was to examine the evolution of the analytical performance specifications (APS) used in External Quality Assurance (EQA) schemes, as well as the efficacy of a category 1 EQA ...
Concepción González Rodríguez,MªBelén Aparicio Hernández,Inmaculada Alarcón Torres
Concepción González Rodríguez
Anti-deoxyribonucleic acid (DNA) antibodies in the clinical laboratory are intimately linked to the diagnosis and monitoring of systemic lupus erythematosus (SLE); however, the characteristics of the analytical methods and the properties of...
Armando Raúl Guerra Ruiz,Javier Crespo,Rosa Maria López Martínez et al.
Armando Raúl Guerra Ruiz et al.
Elevated plasma bilirubin levels are a frequent clinical finding. It can be secondary to alterations in any stage of its metabolism: (a) excess bilirubin production (i.e., pathologic hemolysis); (b) impaired liver uptake, with elevation of ...
Management of post-analytical processes in the clinical laboratory according to ISO 15189:2012. Considerations about the management of clinical samples, ensuring quality of post-analytical processes, and laboratory information management [0.03%]
临床实验室ISO 15189：2012文件关于分析后过程的管理。关于样本管理，保证分析后的质量流程和实验室信息管理的考量
Mᵃ Libòria López Yeste,Antonia R Pons Mas,Leonor Guiñón Muñoz et al.
Mᵃ Libòria López Yeste et al.
ISO 15189:2012 establishes the requirements for clinical sample management, ensuring quality of process and laboratory information management. The accreditation authority, ENAC in Spain, established the requirements for the authorized use o...
Maria-José Castro-Castro,Lourdes Sánchez-Navarro
Maria-José Castro-Castro
Objectives: Change limits, more commonly called delta check, are those in which a change in a patient's measured result in relation to their corresponding preceding measurement is suspected of being erroneous and should b...
María Santamaría González,María Ángels Ruiz Mínguez,María Monsalud Arrebola Ramírez et al.
María Santamaría González et al.
Objectives: Clinical practice guidelines (CPGs) are recommendations based on a systematic review of scientific evidence that are intended to help healthcare professionals and patients make the best clinical decisions. CPG...
Javier Escalada San Martín
Javier Escalada San Martín
Real-world assessment of Fluorecare SARS-CoV-2 Spike Protein Test Kit [0.03%]
Fluorecare SARS-CoV-2刺突蛋白测试试剂盒的现实世界评估
Gian Luca Salvagno,Gianluca Gianfilippi,Laura Pighi et al.
Gian Luca Salvagno et al.
Objectives: Since commercial SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) antigen rapid detection tests (Ag-RDTs) display broad diagnostic efficiency, this study aimed to evaluate the clinical performance ...
A novel variant in the COL4A3 gene: etiology of Alport syndrome type 2 in a 38-year-old male with suspected hereditary kidney disease [0.03%]
COL4A3基因的新变异：一位疑似遗传性肾脏疾病的38岁男性Alport综合征II型病因
Paula Sienes Bailo,José Luis Bancalero Flores,Raquel Lahoz Alonso et al.
Paula Sienes Bailo et al.
Objectives: Patients with Alport syndrome develop progressive kidney function deterioration, sensorineural hearing loss, and ocular abnormalities. This condition is caused by mutations in COL4A5 (X-linked inheritance), CO...