Novel Computational Approach to Predict Off-Target Interactions for Small Molecules [0.03%]
一种预测小分子脱靶相互作用的新型计算方法
Mohan S Rao,Rishi Gupta,Michael J Liguori et al.
Mohan S Rao et al.
Most small molecule drugs interact with unintended, often unknown, biological targets and these off-target interactions may lead to both preclinical and clinical toxic events. Undesired off-target interactions are often not detected using c...
Gregory R Hart,Bradley J Nartowt,Wazir Muhammad et al.
Gregory R Hart et al.
Purpose: Screening the general population for ovarian cancer is not recommended by every major medical or public health organization because the harms from screening outweigh the benefit it provides. To improve ovarian cancer detection and ...
Assessment of Drug-Induced Toxicity Biomarkers in the Brain Microphysiological System (MPS) Using Targeted and Untargeted Molecular Profiling [0.03%]
基于靶向和非靶向分子谱分析的脑器官芯片中药物诱导毒性标志物评价研究
Sara G Mina,Begum Alaybeyoglu,William L Murphy et al.
Sara G Mina et al.
Early assessment of adverse drug effects in humans is critical to avoid long-lasting harm. However, current approaches for early detection of adverse effects still lack predictive and organ-specific biomarkers to evaluate undesired response...
Link Definition Ameliorating Community Detection in Collaboration Networks [0.03%]
改进链接定义以优化协作网络中的社区发现算法
Saharnaz Dilmaghani,Matthias R Brust,Apivadee Piyatumrong et al.
Saharnaz Dilmaghani et al.
Collaboration networks are defined as a set of individuals who come together and collaborate on particular tasks such as publishing a paper. The analysis of such networks permits to extract knowledge on the structure and patterns of communi...
Essa Alhazmi,Nazim Choudhury,Sameera Horawalavithana et al.
Essa Alhazmi et al.
This data-driven study focuses on characterizing and predicting mobility of players between gaming servers in two popular online games, Team Fortress 2 and Counter Strike: Global Offensive. Understanding these patterns of mobility between g...
Jacob Stuivenvolt-Allen,Simon S-Y Wang
Jacob Stuivenvolt-Allen
Anomalously cold winters with extreme storms strain natural gas (NG) markets due to heightened demand for heating and electricity generation. While extended weather forecasting has become an indicator for NG management, seasonal (2-3 month)...
Including Vulnerable Populations in the Assessment of Data From Vulnerable Populations [0.03%]
包括脆弱群体在内的数据评估中的脆弱人群考虑
Latifa Jackson,Caitlin Kuhlman,Fatimah Jackson et al.
Latifa Jackson et al.
Data science has made great strides in harnessing the power of big data to improve human life across a broad spectrum of disciplines. Unfortunately this informational richesse is not equitably spread across human populations. Vulnerable pop...
Global Awareness Landscape for Ailments-A Twitter Based Microscopic View Into Thought Processes of People [0.03%]
基于Twitter的全球疾病认知微观分析
Durga Toshniwal,Soumya Somani,Rohit Aggarwal et al.
Durga Toshniwal et al.
In this day and age, people face a lot of stress due to the fast pace of life. Due to this, people in today's digital age, suffer from a plethora of ailments. It is universally accepted that a greater awareness of ailments and their corresp...
Twitter Response to Munich July 2016 Attack: Network Analysis of Influence [0.03%]
2016年慕尼黑袭击事件后推特用户的反应——影响网络分析
Ivan Bermudez,Daniel Cleven,Ralucca Gera et al.
Ivan Bermudez et al.
Social Media platforms in Cyberspace provide communication channels for individuals, businesses, as well as state and non-state actors (i.e., individuals and groups) to conduct messaging campaigns. What are the spheres of influence that aro...
Prem Kumar,Puneet Verma,Anurag Singh et al.
Prem Kumar et al.
In recent years there has been a growing interest in simulating competitive markets to find out the efficient ways to advertise a product or spread an ideology. Along this line, we consider a binary competitive contagion process where two i...