Deterministic chaos in the self-assembly of β sheet nanotubes from an amphipathic oligopeptide [0.03%]
两亲寡肽自组装形成β片纳米管中的确定性混沌
Fengbin Wang,Ordy Gnewou,Shengyuan Wang et al.
Fengbin Wang et al.
The self-assembly of designed peptides into filaments and other higher-order structures has been the focus of intense interest because of the potential for creating new biomaterials and biomedical devices. These peptide assemblies have also...
Reflections on hosting summer undergraduate researchers in the midst of a pandemic [0.03%]
在大流行中接待暑期大学生研究员的反思
Arynn O Gallegos,Ghada H Ahmed,Tracy H Schloemer et al.
Arynn O Gallegos et al.
The COVID-19 pandemic continues to impact nearly every aspect of our lives, including academic research. In this Matter of Opinion, we reflect on hosting both in-person and virtual undergraduate students during these challenging times. ...
Cryo-EM structures of atomic surfaces and host-guest chemistry in metal-organic frameworks [0.03%]
金属有机框架中原子表面和主客体化学的低温电子显微镜结构
Yuzhang Li,Kecheng Wang,Weijiang Zhou et al.
Yuzhang Li et al.
Host-guest interactions govern the chemistry of a broad range of functional materials, but direct imaging using conventional transmission electron microscopy (TEM) has not been possible. This problem is exacerbated in metal-organic framewor...
Xiuying Li,Hejian Xiong,Nicholas Rommelfanger et al.
Xiuying Li et al.
Understanding the signal transmission and processing within the central nervous system (CNS) is a grand challenge in neuroscience. The past decade has witnessed significant advances in the development of new tools to address this challenge....
Low-cost biosensor for rapid detection of SARS-CoV-2 at the point of care [0.03%]
低成本的点护理SARS-CoV-2快速检测生物传感器
Marcelo D T Torres,William R de Araujo,Lucas F de Lima et al.
Marcelo D T Torres et al.
SARS-CoV-2, the virus that causes COVID-19, has killed over 3 million people worldwide. Despite the urgency of the current pandemic, most available diagnostic methods for COVID-19 use RT-PCR to detect nucleic acid sequences specific to SARS...
Min Chen,Jillian Rosenberg,Xiaolei Cai et al.
Min Chen et al.
SARS-CoV-2 enters host cells through its viral spike protein binding to angiotensin-converting enzyme 2 (ACE2) receptors on the host cells. Here, we show that functionalized nanoparticles, termed "Nanotraps," completely inhibited SARS-CoV-2...
David H Kohn
David H Kohn
This manuscript reports the development of a new multi-functional biomaterial to treat periodontal disease that possesses antimicrobial-as well as adhesive-properties and supports bone regeneration. The impact of this work is larger than ju...
Biomaterial-based immunoengineering to fight COVID-19 and infectious diseases [0.03%]
基于生物材料的免疫工程在抗击COVID-19和其他传染病中的应用
Jana Zarubova,Xuexiang Zhang,Tyler Hoffman et al.
Jana Zarubova et al.
Infection by SARS-CoV-2 virus often induces the dysregulation of immune responses, tissue damage, and blood clotting. Engineered biomaterials from the nano- to the macroscale can provide targeted drug delivery, controlled drug release, loca...
Symbiotic Photosynthetic Oxygenation within 3D-Bioprinted Vascularized Tissues [0.03%]
三维血管活体组织的共生光合作用氧合功能研究
Sushila Maharjan,Jacqueline Alva,Cassandra Cámara et al.
Sushila Maharjan et al.
In this study, we present the photosynthetic oxygen (O2) supply to mammalian cells within a volumetric extracellular matrix-like construct, whereby a three-dimensional (3D)-bioprinted fugitive pattern encapsulating unicellular green algae, ...
Xu Zhang,Sheng Wang,Guohui Cheng et al.
Xu Zhang et al.
Chemotherapy serves as one of the most effective approaches in numerous tumor treatments but also suffers from the limitations of low bioavailability and adverse side effects due to premature drug leakage. Therefore, it is crucial to realiz...