Autonomous Discovery of Functional Random Heteropolymer Blends through Evolutionary Formulation Optimization [0.03%]
通过进化配方优化自主发现功能随机杂聚物组合物
Guangqi Wu,Tianyi Jin,Alfredo Alexander-Katz et al.
Guangqi Wu et al.
While developing new polymers typically requires years of investigation, blending existing polymers offers a cost-effective strategy to create new materials. However, developing functional polymer blends is often a slow and challenging proc...
Sustained exposure to multivalent antigen-decorated nanoparticles generates broad anti-coronavirus responses [0.03%]
带有多种抗原的纳米粒子的持续暴露可产生广谱抗冠状病毒反应
Julie Baillet,John H Klich,Ben S Ou et al.
Julie Baillet et al.
The threat of future coronavirus pandemics requires developing effective vaccine technologies that provide broad and long-lasting protection against circulating and emerging strains. Here we report a multivalent liposomal hydrogel vaccine t...
Sustainable Conversion of Husk into Viscoelastic Hydrogels for Value-Added Biomedical Applications [0.03%]
稻壳可持续转化为用于高附加值生物医学应用的粘弹性水凝胶
Changxu Sun,Jiping Yue,Pengju Li et al.
Changxu Sun et al.
Natural plants provide a wealth of valuable materials for healthcare, with much of their potential often overlooked in what is commonly considered waste. This study focuses on the Malva Nut Tree (Sterculia lychnophora Hance), whose fruit, P...
Tension in the ranks: Cooperative cell contractions drive force-dependent collagen assembly in human fibroblast culture [0.03%]
细胞内的张力：协同的细胞收缩驱动人成纤维细胞培养中与力量相关的胶原蛋白组装
Alexandra A Silverman,Jason D Olszewski,Seyed Mohammad Siadat et al.
Alexandra A Silverman et al.
Currently, there is no mechanistic model that fully explains the initial synthesis and organization of durable animal structure. As a result, our understanding of extracellular matrix (ECM) development and pathologies (e.g., persistent fibr...
Innate immunity-modulating nanobiomaterials for controlling inflammation resolution [0.03%]
用于控制炎症消退的固有免疫调节纳米生物材料
Yongjiang Li,Wei Chen,Seyoung Koo et al.
Yongjiang Li et al.
The acute inflammatory response is an inherent protective mechanism, its unsuccessful resolution can contribute to disease pathogenesis and potentially lead to death. Innate immune cells are the first line of host defenders and play a subst...
Erratum: Ultrathin Metal-Organic-Layer Mediated Radiotherapy-Radiodynamic Therapy [0.03%]
致读者的一封信：超薄金属有机层介导的放射疗法-放射动力疗法
Kaiyuan Ni,Guangxu Lan,Christina Chan et al.
Kaiyuan Ni et al.
[This corrects the article PMC7442115.].
Published Erratum
Matter. 2024 May 1;7(5):1909. DOI:10.1016/j.matt.2024.04.003 2024
Stiff Hydrogel Encapsulation Retains Mesenchymal Stem Cell Stemness for Regenerative Medicine [0.03%]
刚性水凝胶包封保持间充质干细胞的干性以用于再生医学
Bo Li,Liyuan Zhang,Yuan Yin et al.
Bo Li et al.
Mesenchymal stem cell (MSC) stands as a prominent choice in regenerative medicine, yet their therapeutic potential remains controversial due to challenges in maintaining lineage and viability. As directly injected MSCs are quickly cleared b...
Alex Lammers,Heng-Hua Hsu,Subramanian Sundaram et al.
Alex Lammers et al.
Tissue engineering has long sought to rapidly generate perfusable vascularized tissues with vessel sizes spanning those seen in humans. Current techniques such as biological 3D printing (top-down) and cellular self-assembly (bottom-up) are ...
Biophysical characterization of synthetic adhesins for predicting and tuning engineered living material properties [0.03%]
合成粘附素的生物物理表征以预测和调节工程化活性材料性能
Stefana A Costan,Paul M Ryan,Honesty Kim et al.
Stefana A Costan et al.
Bacterial synthetic multicellular systems are promising platforms for engineered living materials (ELMs) for medical, biosynthesis, environmental, and smart materials applications. Recent advancements in genetically encoded adhesion toolkit...
Veronica Cunitz,Evan Stacy,Penelope Jankoski et al.
Veronica Cunitz et al.
At the University of Minnesota, scientists explore the application of machine learning to screen a multiparametric library of polymers to investigate the relationship between polymer attributes, payload type, and biological outcomes to opti...