Biofilm dispersion: The key to biofilm eradication or opening Pandora's box? [0.03%]
生物被膜的扩散：清除生物被膜的关键还是打开潘多拉魔盒？
Jasper Wille,Tom Coenye
Jasper Wille
Biofilms are extremely difficult to eradicate due to their decreased antibiotic susceptibility. Inducing biofilm dispersion could be a potential strategy to help combat biofilm-related infections. Mechanisms of biofilm dispersion can basica...
Luis Zea,Robert J C McLean,Tony A Rook et al.
Luis Zea et al.
Biofilms, surface-adherent microbial communities, are associated with microbial fouling and corrosion in terrestrial water-distribution systems. Biofilms are also present in human spaceflight, particularly in the Water Recovery System (WRS)...
Phenazine oxidation by a distal electrode modulates biofilm morphogenesis [0.03%]
远程电极氧化吩嗪调控生物被膜形态发生
William Cole Cornell,Yihan Zhang,Anastasia Bendebury et al.
William Cole Cornell et al.
Microbes living in biofilms, dense assemblages of cells, experience limitation for resources such as oxygen when cellular consumption outpaces diffusion. The pathogenic bacterium Pseudomonas aeruginosa has strategies for coping with hypoxia...
Genetic determinants of Pseudomonas aeruginosa fitness during biofilm growth [0.03%]
铜绿假单胞菌生物被膜生长的适应性遗传决定因素分析
Silvia Schinner,Florian Engelhardt,Matthias Preusse et al.
Silvia Schinner et al.
Pseudomonas aeruginosa is an environmental bacterium and an opportunistic human pathogen. It is also a well-established model organism to study bacterial adaptation to stressful conditions, such as those encountered during an infection proc...
Agaric acid reduces Salmonella biofilm formation by inhibiting flagellar motility [0.03%]
agaric酸通过抑制鞭毛运动性来减少沙门氏菌生物被膜的形成
Bram Lories,Tom E R Belpaire,Anna Yssel et al.
Bram Lories et al.
Salmonella biofilms are a common cause of contaminations in the food or feed industry. In a screening for novel compounds to combat biofilm-associated foodborne outbreaks, we identified agaric acid as a Salmonella Typhimurium biofilm inhibi...
Surfactin production is not essential for pellicle and root-associated biofilm development of Bacillus subtilis [0.03%]
表面活性素的产生并非凝胶状生物被膜和根相关生物被膜发育所必需的因素
Maude Thérien,Heiko T Kiesewalter,Emile Auria et al.
Maude Thérien et al.
Secondary metabolites have an important impact on the biocontrol potential of soil-derived microbes. In addition, various microbe-produced chemicals have been suggested to impact the development and phenotypic differentiation of bacteria, i...
The establishment of the CBE launched biofilms as a field of specialized research [0.03%]
CBE的建立开启了生物被膜研究的专门化领域
Matthew W Fields,Paul Sturman,Skip Anderson
Matthew W Fields
The Center for Biofilm Engineering was the first center of excellence focused on biofilms and was originally funded through the Engineering Research Center Program from the U.S. National Science Foundation. After almost 30 years, biofilm co...
Binu Kundukad,Gayathri Udayakumar,Erin Grela et al.
Binu Kundukad et al.
Weak acids such as acetic acid and N-acetyl cysteine (NAC) at pH less than their pKa can effectively eradicate biofilms due to their ability to penetrate the biofilm matrix and the cell membrane. However, the optimum conditions for their ac...
Forming and waking dormant cells: The ppGpp ribosome dimerization persister model [0.03%]
潜伏细胞的形成和唤醒：关于警报物(ppGpp)介导的核糖体二聚化Persisters模型
Thomas K Wood,Sooyeon Song
Thomas K Wood
Procaryotes starve and face myriad stresses. The bulk population actively resists the stress, but a small population weathers the stress by entering a resting stage known as persistence. No mutations occur, and so persisters behave like wil...
Erin S Gloag,Stefania Fabbri,Daniel J Wozniak et al.
Erin S Gloag et al.
It has long been recognized that biofilms are viscoelastic materials, however the importance of this attribute to the survival and persistence of these microbial communities is yet to be fully realized. Here we review work, which focuses on...