The natriuretic peptide receptor agonist osteocrin disperses Pseudomonas aeruginosa biofilm [0.03%]
钠尿肽受体激动剂osteocrin分散铜绿假单胞菌生物被膜
Melissande Louis,Ali Tahrioui,Courtney J Tremlett et al.
Melissande Louis et al.
Biofilms are highly tolerant to antimicrobials and host immune defense, enabling pathogens to thrive in hostile environments. The diversity of microbial biofilm infections requires alternative and complex treatment strategies. In a previous...
Silver-doped bioactive glass fibres as a potential treatment for wound-associated bacterial biofilms [0.03%]
掺银生物活性玻璃纤维有望成为治疗伤口相关细菌生物膜的药物
Sandeep Shirgill,Gowsihan Poologasundarampillai,Sara Jabbari et al.
Sandeep Shirgill et al.
Chronic wounds are a drain on global health services and remain a major area of unmet clinical need. Chronic wounds are characterised by a stable and stubborn bacterial biofilm which hinders innate immune response and delays or prevents wou...
Furanone loaded aerogels are effective antibiofilm therapeutics in a model of chronic Pseudomonas aeruginosa wound infection [0.03%]
载有糠酮的气凝胶能有效治疗慢性绿脓杆菌伤口感染模型中的生物膜感染
Chris R Proctor,Megan G Taggart,Barry M G O&#x;Hagan et al.
Chris R Proctor et al.
Almost 80% of chronic wounds have a bacterial biofilm present. These wound biofilms are caused by a range of organisms and are often polymicrobial. Pseudomonas aeruginosa is one of the most common causative organisms in wound infections and...
Extracellular succinate induces spatially organized biofilm formation in Clostridioides difficile [0.03%]
细胞外琥珀酸可诱导艰难梭菌分区域生物被膜形成
Emile Auria,Julien Deschamps,Romain Briandet et al.
Emile Auria et al.
Clostridioides difficile infection associated to gut microbiome dysbiosis is the leading cause for nosocomial diarrhea. The ability of C. difficile to form biofilms has been progressively linked to its pathogenesis as well as its persistenc...
Cold atmospheric pressure plasma-antibiotic synergy in Pseudomonas aeruginosa biofilms is mediated via oxidative stress response [0.03%]
低温等离子体-抗生素协同作用于铜绿假单胞菌生物被膜通过氧化应激反应介导
Jordanne-Amee Maybin,Thomas P Thompson,Padrig B Flynn et al.
Jordanne-Amee Maybin et al.
Cold atmospheric-pressure plasma (CAP) has emerged as a potential alternative or adjuvant to conventional antibiotics for the treatment of bacterial infections, including those caused by antibiotic-resistant pathogens. The potential of sub-...
María Fernández-Billón,Aina E Llambías-Cabot,Elena Jordana-Lluch et al.
María Fernández-Billón et al.
Pseudomonas aeruginosa is a major cause of life-threatening acute infections and life-long lasting chronic infections. The characteristic biofilm mode of life in P. aeruginosa chronic infections severely limits the efficacy of antimicrobial...
Olabayo H Ajetunmobi,Hamid Badali,Jesus A Romo et al.
Olabayo H Ajetunmobi et al.
Virtually all Candida species linked to clinical candidiasis are capable of forming highly resistant biofilms on different types of surfaces, which poses an additional significant threat and further complicates therapy of these infections. ...
Anti-infective characteristics of a new Carbothane ventricular assist device driveline [0.03%]
具有抗菌特性的新型Carbothane心室辅助装置导线圈
Yue Qu,David McGiffin,Lina Duque Sanchez et al.
Yue Qu et al.
Objectives: Driveline infections are a major complication of ventricular assist device (VAD) therapy. A newly introduced Carbothane driveline has preliminarily demonstrated anti-infective potential against driveline infec...
Staphylococcus aureus strains exhibit heterogenous tolerance to direct cold atmospheric plasma therapy [0.03%]
金黄色葡萄球菌菌株对直接冷等离子体治疗表现出异质性耐受性
Abdullah Baz,Ahmed Bakri,Mark Butcher et al.
Abdullah Baz et al.
The global clinical and socioeconomic impact of chronic wounds is substantial. The main difficulty that clinicians face during the treatment of chronic wounds is the risk of infection at the wound site. Infected wounds arise from an accumul...
Mojtaba Khani,Mads Frederik Hansen,Susanne Knøchel et al.
Mojtaba Khani et al.
Many companies in the food industry apply reverse osmosis (RO) membranes to ensure high-quality reuse of water. Biofouling is however, a common, recalcitrant and recurring problem that blocks transport over membranes and decreases the water...