Fluorene derivatives as potent antifungal and antibiofilm agents against fluconazole-resistant Candida albicans [0.03%]
茋衍生物作为抗氟康唑耐药白色念珠菌的抗真菌和抗生物膜剂
Oluwatosin Oluwaseun Faleye,Amra Yunus,Jin-Hyung Lee et al.
Oluwatosin Oluwaseun Faleye et al.
Candida albicans ranks as one of the most common causes of fungal sepsis in hospitalized patients around the world with an increasing mortality rate. The current antifungal drugs in use face several limitations including fungal resistance d...
Formation of CO2-dependent small-colony variants (SCVs) in methicillin-resistant Staphylococcus aureus mediated by a single point mutation in mpsB [0.03%]
由mpsB点突变介导的耐甲氧西林金黄色葡萄球菌CO2依赖性小 колониальные формы(SCV)的形成
Sisi Chen,Wanyang Dong,Song Li et al.
Sisi Chen et al.
Introduction: Staphylococcus aureus is a major human pathogen and the emergence of small colony variants (SCVs) makes the treatment of S. aureus infections more challenging. The mechanism of CO2-dependent SCVs (CO2-SCVs) ...
Dynamic visualization of extracellular matrix components in S. aureus colony biofilms reveals functional amyloids leading to the formation of cap-like structures [0.03%]
S.aureus菌落生物被膜中细胞外基质组分的动态可视化揭示了帽状结构形成的功能性淀粉样体
Tianqi Zhang,Julian Bär,Lovisa Risberg et al.
Tianqi Zhang et al.
Staphylococcus aureus infections represent a clinical challenge due to their propensity to form biofilms and the increasing prevalence of antibiotic resistance. The ability of S. aureus to form biofilm affects clinical outcome, but techniqu...
Farnesol emulsion for elimination of Pseudomonas aeruginosa biofilm in a 3D airway model of cystic fibrosis [0.03%]
法尼醇乳剂在囊性纤维化三维气道模型中消除绿脓杆菌生物被膜的研究
Li Tan,Khiry Sutton,Sean V Murphy et al.
Li Tan et al.
Cystic fibrosis (CF), a life-shortening genetic disease, is hallmarked by mucus obstruction, respiratory deficiency, and chronic bacterial infections. Pseudomonas aeruginosa is the most common virulent respiratory pathogen that is detriment...
Potassium iodide enhances the antimicrobial activity of plasma-activated water [0.03%]
碘化钾增强等离子体活化水的抗菌活性
Laura A McClenaghan,Thomas P Thompson,Akash Shambharkar et al.
Laura A McClenaghan et al.
Plasma-activated water (PAW) is a promising disinfection strategy that generates a complex mixture of reactive oxygen and nitrogen species (ROS/RNS), including hydrogen peroxide (H2O2), nitrate (NO3 -), and transient oxidants, in an acidic ...
Ambroxol hydrochloride as an antibiofilm agent synergizes with tetracycline antibiotics against mature biofilms of multidrug-resistant Klebsiella pneumoniae [0.03%]
盐酸安溴索作为一种抗生物膜剂可协同四环素类抗生素对抗多重耐药肺炎克雷伯菌成熟生物被膜
TengLi Zhang,XunQin Gao,MengTing Liu et al.
TengLi Zhang et al.
Multidrug-resistant Klebsiella pneumoniae (MDR-KP) is a major pathogen responsible for hospital-acquired infections, associated with high morbidity and mortality. Biofilm formation plays a key role in the pathogenicity of MDR-KP and contrib...
Dual red and near-infrared LED therapy inhibits MRSA biofilm in otitis media [0.03%]
双波长红光和近红外LED疗法可抑制中耳炎中的金黄色葡萄球菌生物被膜形成
Yoo-Seung Ko,Eun-Ji Gi,Sungsu Lee et al.
Yoo-Seung Ko et al.
Otitis media (OM), particularly when caused by methicillin-resistant Staphylococcus aureus (MRSA), can become refractory due to biofilm formation, which contributes to resistance against conventional antimicrobial treatments. Photobiomodula...
Comparative transcriptomics analysis of the Oleidesulfovibrio alaskensis G20 biofilms grown on copper and polycarbonate surfaces [0.03%]
铜和聚碳酸酯表面培养的Oleisulfovibrio alaskensis G20菌落的转录组分析
Priya Saxena,Dipayan Samanta,Payal Thakur et al.
Priya Saxena et al.
Sulfate-reducing bacterial (SRB) biofilms are prevalent across diverse environments, playing key roles in biogeochemical sulfur cycling while also contributing to industrial challenges such as biofouling and biocorrosion. Understanding the ...
Proteomic identification of PA2146 as a biofilm marker of Pseudomonas aeruginosa on endoscope channel material [0.03%]
蛋白组学鉴定绿脓杆菌内镜管道材料生物膜标志物PA2146蛋白质
Koen van der Ploeg,Corné P de Vogel,Corné H W Klaassen et al.
Koen van der Ploeg et al.
Study background and aims: Pseudomonas aeruginosa can persistently contaminate endoscopes by forming biofilms within internal channels, complicating both detection and eradication. Current microbiological surveillance met...
Plasma-activated water accelerates wound healing and reduces Staphylococcus aureus infection in vivo [0.03%]
等离子活化水加速伤口愈合并减少体内金黄色葡萄球菌感染
Adrian I Abdo,Hang T Nguyen,Laurine D Kaul et al.
Adrian I Abdo et al.
Chronic wound infections are notoriously difficult to treat due to bacterial biofilms - protective communities of microbes that can resist antibiotics and host defenses. With rising antimicrobial resistance, there is an urgent need for non-...