Zachary Van Roy,Tammy Kielian
Zachary Van Roy
Biofilms are bacterial communities surrounded by a polymeric matrix that can form on implanted materials and biotic surfaces, resulting in chronic infection that is recalcitrant to immune- and antibiotic-mediated clearance. Therefore, biofi...
A simulated microgravity biofilm reactor with integrated microfabricated sensors: Advancing biofilm studies in near-space conditions [0.03%]
集成微加工传感器的模拟微重力生物膜反应器：在近空间条件下推进生物膜研究
Haley M Ketteler,Erick L Johnson,Matthew McGlennen et al.
Haley M Ketteler et al.
Studying biofilms in a microgravity environment currently relies on one of two scenarios, collecting planktonic aggregates in rotating wall vessels or performing experiments in the microgravity environment of space on the International Spac...
Cellulophaga algicola alginate lyase and Pseudomonas aeruginosa Psl glycoside hydrolase inhibit biofilm formation by Pseudomonas aeruginosa CF2843 on three-dimensional aggregates of lung epithelial cells [0.03%]
细胞噬藻菌海藻酸裂解酶和绿假单胞菌Psl糖苷水解酶抑制肺上皮细胞三维聚合体中绿假单胞菌CF2843的生物膜形成
Neetu,Shilpee Pal,Srikrishna Subramanian et al.
Neetu et al.
Pseudomonas aeruginosa is an opportunistic pathogen that produces a biofilm containing the polysaccharides, alginate, Psl, and Pel, and causes chronic lung infection in cystic fibrosis patients. Others and we have previously explored the us...
In vivo efficacy of a refillable intrawound drug delivery device in a sheep model of biofilm-compromised open fracture-related infection [0.03%]
在生物膜受影响的开放性骨折相关感染的绵羊模型中，可充填的伤口内药物输送装置的体内疗效
Dustin Williams,David Rothberg,Walker Kay et al.
Dustin Williams et al.
Open fracture-related infection challenges persist in healthcare. From the time open fractures were defined ∼50 years ago, infection rates have gone essentially unchanged. Contributing factors include compromised vasculature, biofilm, and ...
Safae Oukrich,Jane Hong,Mariël Leon-Grooters et al.
Safae Oukrich et al.
The single most common microbe causing cardiovascular infections is Staphylococcus aureus (S. aureus). S. aureus produces coagulase that converts fibrinogen to fibrin, which is incorporated into biofilms. This process aids in adherence to i...
Alexandra Sousa,Rutuparna Kulkarni,Mona Johannessen et al.
Alexandra Sousa et al.
Biofilms present a great challenge in antimicrobial therapy due to their inherent tolerance to conventional antibiotics, promoting the need for advanced drug delivery strategies that improve therapy. While various nanoparticles (NPs) have b...
A comprehensive analysis of the effect of quorum-sensing molecule 3-oxo-C12-homoserine lactone on Candida auris and Candida albicans [0.03%]
群体感应分子3-氧代-C12-同源丝氨酸内酯对白念珠菌和耳念珠菌的影响的全面分析
Fruzsina Kovács,Ágnes Jakab,Noémi Balla et al.
Fruzsina Kovács et al.
Candida auris occupies similar niches in various infections as Pseudomonas aeruginosa; however, the details of their interspecies communication remain largely unknown. To gain deeper insights into this relationship, phenotypic and transcrip...
Co-culture biofilm patterns among different Pseudomonas aeruginosa clones from cystic fibrosis patients [0.03%]
囊性纤维化患者不同铜绿假单胞菌克隆的共培养生物膜模式
Irene Cadenas-Jiménez,Morten Levin Rybtke,Doaa Higazy et al.
Irene Cadenas-Jiménez et al.
Background: Pseudomonas aeruginosa chronic lung infection is the leading cause of death in the cystic fibrosis (CF) population. The high genome versatility of this microorganism allows it to adapt to the hostile CF lung w...
Legionella pneumophila response to shifts in biofilm structure mediated by hydrodynamics [0.03%]
由水力条件介导的生物膜结构转变造成的嗜肺军团菌的反应
Ana Rosa Silva,C William Keevil,Ana Pereira
Ana Rosa Silva
Preventing legionellosis in water systems demands effective hydrodynamic management and biofilm mitigation. This study investigates the complex relationship between hydrodynamics (80 RPM and stagnation), biofilm mesoscale structure and Legi...
Development of a tri-species wound model for studying fungal-bacterial interactions and antimicrobial therapies [0.03%]
三物种伤口模型的开发，用于研究真菌细菌相互作用和抗菌疗法
Stine Sørensen,Lasse Kvich,Yijuan Xu et al.
Stine Sørensen et al.
Chronic wounds are increasing in numbers and biofilm-producing bacteria are highly prevalent in these wounds and often create resilient polymicrobial infections. Moreover, estimates suggest that up to 23 % of wounds contain fungi, particula...