Mechanical strain-mediated reduction in RANKL expression is associated with RUNX2 and BRD2 [0.03%]
机械牵张抑制RANKL表达与RUNX2和BRD2相关性研究
Gabriel L Galea,Christopher R Paradise,Lee B Meakin et al.
Gabriel L Galea et al.
Mechanical loading-related strains trigger bone formation by osteoblasts while suppressing resorption by osteoclasts, uncoupling the processes of formation and resorption. Osteocytes may orchestrate this process in part by secreting scleros...
The Y-chromosome of the Soliga, an ancient forest-dwelling tribe of South India [0.03%]
印度南部一支古老森林部落soliga的y染色体
Diane J Rowold,Shilpa Chennakrishnaiah,Tenzin Gayden et al.
Diane J Rowold et al.
A previous autosomal STR study provided evidence of a connection between the ancient Soliga tribe at the southern tip of the Indian subcontinent and Australian aboriginal populations, possibly reflecting an eastbound coastal migration circa...
Amelia Meecham,John F Marshall
Amelia Meecham
Integrin αvβ6 is a membrane-spanning heterodimeric glycoprotein involved in wound healing and the pathogenesis of diseases including fibrosis and cancer. Therefore, it is of great clinical interest for us to understand the molecular mecha...
Putative circumsporozoite protein (CSP) of Plasmodium vivax is considerably distinct from the well-known CSP and plays a role in the protein ubiquitination pathway [0.03%]
假定的周蛋白（CSP）与已知的疟原虫蛋白有较大区别，并且在蛋白质泛素化途径中发挥作用
Manoswini Dash,Veena Pande,Abhinav Sinha
Manoswini Dash
Amidst technical challenges which limit successful culture and genetic manipulation of P. vivax parasites, we used a computational approach to identify a critical target with evolutionary significance. The putative circumsporozoite protein ...
Inferring changes in histone modification during cell differentiation by ancestral state estimation based on phylogenetic trees of cell types: Human hematopoiesis as a model case [0.03%]
基于细胞类型系谱树的祖先状态估算推断细胞分化过程中的组蛋白修饰变化：以人类造血为模型案例
Kanako O Koyanagi
Kanako O Koyanagi
Revealing the landscape of epigenetic changes in cells during differentiation is important for understanding the development of organisms. In this study, to infer such epigenetic changes during human hematopoiesis, ancestral state estimatio...
Association of FTO and ADRB2 gene variation with energy restriction induced adaptations in resting energy expenditure and physical activity [0.03%]
FTO和ADRB2基因多态性与能量限制诱导的静息能量消耗和身体活动适应的关系
Stefan G J A Camps,Sanne P M Verhoef,Freek G Bouwman et al.
Stefan G J A Camps et al.
Background: Energy restriction induces adaptations in resting energy expenditure (REE) and physical activity; inter-individual variability could be ascribed to genetic predisposition.The aim was to examine if changes in R...
VitiVar: A locus specific database of vitiligo associated genes and variations [0.03%]
VitiVar：一个与白癜风相关基因及变异的定位数据库
Iti Gupta,Ankita Narang,Prateek Singh et al.
Iti Gupta et al.
Vitiligo is the most common skin pigmentation disorder which affects around 1% of the population worldwide. The disease has complex pathogenesis and is of multifactorial etiology, that finally culminates in patchy depigmentation of skin. Ge...
Upregulation of the long non-coding RNA CBR3-AS1 predicts tumor prognosis and contributes to breast cancer progression [0.03%]
长链非编码RNA CBR3-AS1的上调预示肿瘤预后并促进乳腺癌进展
Lingyun Xu,Hong Zhu,Fei Gao et al.
Lingyun Xu et al.
Breast cancer is the most common female malignancy and the major cause of cancer-related death in women. Long non-coding RNAs (lncRNAs), as oncogenic or tumor suppressor factor, involved in the development and progression of various cancers...
Codon usage pattern and predicted gene expression in Arabidopsis thaliana [0.03%]
拟南芥的密码子使用模式与预测基因表达水平之间的关系研究
Satyabrata Sahoo,Shib Sankar Das,Ria Rakshit
Satyabrata Sahoo
The extensive research for predicting highly expressed genes in plant genome sequences has been going on for decades. The codon usage pattern of genes in Arabidopsis thaliana genome is a classical topic for plant biologists for its signific...
Analysis of RAMP3 gene polymorphism with body composition and bone density in young and elderly women [0.03%]
RAMP3基因多态性与青年和老年女性体成分及骨密度的关系分析
Jai Prakash,Maria Herlin,Jitender Kumar et al.
Jai Prakash et al.
Background and aim: The Receptor Activity Modifying Proteins (RAMPs) are a group of accessory proteins, of which there are three in humans, that interact with a number of G-protein coupled receptors (GPCR) and play variou...