Evaluation of a blended learning program designed to improve clinical practice skills in novice healthcare professionals caring for patients with Parkinson's disease [0.03%]
评估一种混合学习项目的设计:该项目旨在提高初级医疗专业人员照护帕金森病患者的临床实践技能
Koichi Nagaki,Wataru Matsushita,Makio Takahashi
Koichi Nagaki
Introduction: Specialized healthcare facilities for Parkinson's disease (PD) patients require professionals with comprehensive knowledge of disease management and palliative care. This intervention study evaluated a blend...
Distinctive cognitive phenotypes in Parkinson's disease patients with GBA mutations and without dementia: a multicentre cross-sectional retrospective study [0.03%]
GBA基因突变帕金森病患者的认知特征及非痴呆患者横断面研究
Chiara Longo,Marco Liccari,Ruggero Bacchin et al.
Chiara Longo et al.
Background: Cognitive impairment is a major non-motor complication of Parkinson's disease (PD). GBA mutations are associated with an increased risk, with PD-GBA+ patients typically showing earlier disease onset and faster...
Gait and balance dysfunction are associated with cognitive performance only in men with Parkinson's disease [0.03%]
步态和平衡功能障碍仅与帕金森病男性患者的认知表现有关
Amy W Amara,Kimberly H Wood,Aya M Miften et al.
Amy W Amara et al.
Introduction: Parkinson's disease (PD) can cause locomotor dysfunction and cognitive impairment and these symptoms are often associated. This study assesses relationships between comprehensive cognitive performance and lo...
A case of Frégoli syndrome following 24-hour levodopa-carbidopa intestinal gel infusion in a patient with Parkinson's disease undergoing STN-DBS [0.03%]
一例接受丘脑底核深部电刺激手术的帕金森病患者在使用左旋多巴-卡比多巴肠凝胶泵持续输注24小时后出现弗洛吉奥综合征的病例报告
Shunsuke Ogata,Katsuo Kimura,Katsuya Abe et al.
Shunsuke Ogata et al.
Regional changes in the prevalence of Parkinson's disease over a ten-year period in the state of Texas [0.03%]
德克萨斯州十年间帕金森病患病率的地区变化
Sean G Young,Kathryn Elwell,Christopher R Watts
Sean G Young
Introduction: Region specific epidemiological knowledge is needed to better help government and private entities plan and develop interventions to address accelerating diagnoses of Parkinson's disease (PD). We measured th...
Exploring behavior, motivation, and barriers to exercise in Parkinson disease [0.03%]
探究帕金森病患者运动行为、动机及障碍因素
Allison M Haussler,Sidney T Baudendistel,Lauren E Tueth et al.
Allison M Haussler et al.
Introduction: Despite extensive evidence for its numerous benefits, many people with Parkinson's disease (PwPD) do not meet recommended exercise guidelines. Past work investigated motivators and barriers to exercise gener...
The impact of mild-to-moderate cortical cognitive deficits on post-operative outcomes in deep brain stimulation for Parkinson's disease: Considerations for patient selection [0.03%]
皮质认知轻至中度缺陷对帕金森病深部脑刺激术后结果的影响及患者选择的考量
Marina Sarno,Scott Harcourt,Annelly Bure-Reyes et al.
Marina Sarno et al.
Introduction: Subcortical deficits in Parkinson's disease (PD) are well studied; however, deep brain stimulation (DBS) risks posed by mild-moderate deficits in semantic fluency, verbal memory storage, and confrontation na...
Analysis of patellar reflex in Parkinson disease patients after an acupuncture treatment protocol - Case series study [0.03%]
针刺治疗帕金森病患者后的膝跳反射分析-病例系列研究
Catarina Ramos Pereira,Jorge Machado,Begoña Criado et al.
Catarina Ramos Pereira et al.
Introduction: The investigation of rigidity physiology in Parkinson's Disease involves the examination of reflexes. Parkinsonian patients often demonstrate reduced sensitivity in polysynaptic reflexes within the leg exten...
GBA genotype-Parkinson's phenotype correlation in a cohort of 252 Italian patients from the Tuscany region [0.03%]
GBA基因型与帕金森表型在意大利托斯卡纳地区252名患者中的关联研究
Rodolfo Tonin,Silvia Ramat,Marina Rinaldi et al.
Rodolfo Tonin et al.
Introduction: heterozygous mutations in the glucocerebrosidase gene (GBA1), encoding the lysosomal enzyme β-glucocerebrosidase (GCase) are the most common genetic risk factor for Parkinson's disease (PD). To assess the f...
Contribution of dopaminergic polymorphisms to levodopa treatment response and drug concentration in Chinese patients with Parkinson's disease [0.03%]
多巴胺能多态性对中国帕金森病患者左旋多巴治疗反应和血药浓度的影响分析
Xiaoqin He,Kai Shi,Chengjun Mo et al.
Xiaoqin He et al.
Background: Levodopa is the mainstay of treatments for Parkinson's disease (PD), but large heterogeneity exists in patient response. Pharmacogenetic studies highlighted that genetic factors may play a relevant influence i...