Beyond the needle: how clinician expertise affects outcomes in the treatment of hemifacial spasm [0.03%]
超越针刺:临床医师的专长如何影响半面痉挛治疗效果
Melissa Luque-Llano,Maria Angelica-Coronel,Yulexy T Alvarado-Vanegas et al.
Melissa Luque-Llano et al.
Background: Hemifacial spasm (HFS) is characterized by abnormal contraction of the muscles innervated by the seventh cranial nerve. It is usually benign and diagnosed clinically. The effectiveness of botulinum toxin (BoNT...
Peng Li-Hua,Lamarana Jallow,Yurong Tan et al.
Peng Li-Hua et al.
Background: Parkinson's disease (PD) is a complex neurodegenerative disorder requiring multidimensional treatment approaches. Recent breakthroughs in precision medicine and growing evidence for music therapy efficacy present new opportuniti...
The impact of pregabalin and gabapentin on essential tremor: a systematic review and meta-analysis [0.03%]
普瑞巴林和加巴喷丁对原发性震颤影响的系统评价和meta分析
Hooman Pourbala,Zhale Nahavandi,Arash Maghsoudlou et al.
Hooman Pourbala et al.
Introduction: Essential tremor (ET) is a common neurological disorder characterized by involuntary rhythmic oscillations. Emerging evidence suggests that gabapentinoids, including gabapentin and pregabalin, may be effecti...
Usability, safety and tolerability of CUE1 vibrotactile device as promising therapeutic approach in orthostatic tremor [0.03%]
用于直立性震颤治疗的CUE1振动触觉装置的有效性、安全性和耐受性研究
Viktoria Azoidou,Alexandra Zirra,Thomas Boyle et al.
Viktoria Azoidou et al.
Introduction: Primary Orthostatic Tremor (POT) is a rare hyperkinetic movement disorder characterized by unsteadiness while standing, often exacerbated by anxiety and fatigue. It significantly impairs quality of life, and...
Verbal fluency is associated with Gait impairment in Progressive Supranuclear Palsy [0.03%]
进行性核上性麻痹患者流畅度与步态障碍的关系
Aminette DSouza,Charalampos Sotirakis,Niall Conway et al.
Aminette DSouza et al.
Introduction: Gait impairment is an important diagnostic criterion for Progressive Supranuclear Palsy (PSP) and may be modulated by specific cognitive domains such as executive function. This study aims to investigate the...
How to dose extended-release carbidopa-levodopa capsules (IPX203, CREXONT®) in patients with Parkinson's disease [0.03%]
如何在帕金森病患者中使用卡比多巴-左旋多巴缓释胶囊(IPX203,CREXONT®)
Robert A Hauser,Yasar Torres-Yaghi,Stanley Fisher et al.
Robert A Hauser et al.
IPX203 (CREXONT®) is a novel, oral, extended-release (ER) carbidopa-levodopa (CD-LD) formulation, designed to rapidly achieve LD plasma concentrations similar to immediate-release (IR) CD-LD and to maintain LD concentrations for a longer d...
Long-term efficacy of deep brain stimulation in PLA2G6-related Parkinson's disease: A case report with literature review [0.03%]
PLA2G6相关帕金森病深部脑刺激长期疗效一例及文献复习
Takashi Tsuboi,Takashi Uematsu,Yoshiki Ito et al.
Takashi Tsuboi et al.
A patient with early-onset PARK14 and novel PLA2G6 variants underwent globus pallidus internus deep brain stimulation, achieving sustained three-year motor and quality-of-life improvements. Although a literature review supports motor benefi...
Functional outcomes in older patients after Parkinson's disease diagnosis in Japan: The LIFE study [0.03%]
日本帕金森病患者诊断后的功能预后:LIFE研究
Masayo Komatsu,Sanyu Ge,Yasuyoshi Kimura et al.
Masayo Komatsu et al.
Background: The association between care needs level (CNL) and functional outcomes after diagnosis in older patients with Parkinson's disease (PD) is unclear. ...
Effects of the continuous subcutaneous infusion of foslevodopa-foscarbidopa on swallowing in patients with Parkinson's disease [0.03%]
连续皮下注射左旋多巴-卡比多巴对帕金森病患者吞咽功能的影响
Makito Hirano,Makoto Samukawa,Chiharu Isono et al.
Makito Hirano et al.
Background: Dysphagia is a potentially fatal symptom of Parkinson's disease (PD) and is characterized by frequent silent aspiration, a known risk factor for aspiration pneumonia. A previous study has reported that the dop...
Fibrinogen is the key factor associated with tremor relief and recurrence after magnetic resonance-guided focused ultrasound thalamotomy [0.03%]
纤维蛋白原是磁共振引导聚焦超声丘脑束状核毁损术止颤及其复发的关键因素
Jiaji Lin,Haoxuan Lu,Xianbing Bian et al.
Jiaji Lin et al.
Introduction: Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is safe and effective for tremor disorders such as essential tremor (ET), but whether preoperative serum profiles mediate tremor recurrence a...