Long-term efficacy of deep brain stimulation in PLA2G6-related Parkinson's disease: A case report with literature review [0.03%]
PLA2G6相关帕金森病深部脑刺激长期疗效一例及文献复习
Takashi Tsuboi,Takashi Uematsu,Yoshiki Ito et al.
Takashi Tsuboi et al.
A patient with early-onset PARK14 and novel PLA2G6 variants underwent globus pallidus internus deep brain stimulation, achieving sustained three-year motor and quality-of-life improvements. Although a literature review supports motor benefi...
Functional outcomes in older patients after Parkinson's disease diagnosis in Japan: The LIFE study [0.03%]
日本帕金森病患者诊断后的功能预后：LIFE研究
Masayo Komatsu,Sanyu Ge,Yasuyoshi Kimura et al.
Masayo Komatsu et al.
Background: The association between care needs level (CNL) and functional outcomes after diagnosis in older patients with Parkinson's disease (PD) is unclear. ...
Effects of the continuous subcutaneous infusion of foslevodopa-foscarbidopa on swallowing in patients with Parkinson's disease [0.03%]
连续皮下注射左旋多巴-卡比多巴对帕金森病患者吞咽功能的影响
Makito Hirano,Makoto Samukawa,Chiharu Isono et al.
Makito Hirano et al.
Background: Dysphagia is a potentially fatal symptom of Parkinson's disease (PD) and is characterized by frequent silent aspiration, a known risk factor for aspiration pneumonia. A previous study has reported that the dop...
Fibrinogen is the key factor associated with tremor relief and recurrence after magnetic resonance-guided focused ultrasound thalamotomy [0.03%]
纤维蛋白原是磁共振引导聚焦超声丘脑束状核毁损术止颤及其复发的关键因素
Jiaji Lin,Haoxuan Lu,Xianbing Bian et al.
Jiaji Lin et al.
Introduction: Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is safe and effective for tremor disorders such as essential tremor (ET), but whether preoperative serum profiles mediate tremor recurrence a...
"Does speech in patients with different Parkinson's disease subtypes decline over time?" [0.03%]
「不同帕金森病亚型患者的言语功能会随时间退化吗？」
Vanessa Brzoskowski Dos Santos,Fernanda Venzke Zardin,Rui Rothe-Neves et al.
Vanessa Brzoskowski Dos Santos et al.
Purpose: This study investigates whether speech changes over time in patients with different motor subtypes of Parkinson's disease (PD). Methods: ...
Speech subtypes are associated with worsened tremor and axial symptoms in Parkinson's disease patients [0.03%]
帕金森病患者的言语亚型与震颤和轴向症状恶化有关
Vanessa Brzoskowski Dos Santos,Rafaela Ravazio,Daniel Teixeira-Dos-Santos et al.
Vanessa Brzoskowski Dos Santos et al.
Background: Parkinson's disease (PD) is a heterogeneous disorder, suggesting the presence of distinct subtypes. Speech data, though easy to collect, remains underutilized in subtyping PD. ...
Longitudinal associations between physical performance and cognition in individuals with Parkinson's disease [0.03%]
帕金森病患者的物理表现与认知的纵向关联
Andrew J Petkus,Ryan P Foreman,Matthew Pilgrim et al.
Andrew J Petkus et al.
Background: Declines in physical performance and cognition commonly occur in people with Parkinson's disease (PwPD) and negatively impacts Quality of Life. Understanding the cross-sectional and longitudinal associations b...
Long term (TEN YEARS) follow-up in a trembling patient with parkinsonian signs without dopaminergic denervation [0.03%]
一名震颤帕金森病患者长期（十年）随访未发现多巴胺能脱髓鞘病变
Luca Angelini,Giulia Paparella,Petra Schwingenschuh et al.
Luca Angelini et al.
Some patients presenting with Parkinson's disease (PD)-like features do not exhibit dopaminergic denervation, complicating clinical categorization. This case report describes a patient with a long-standing upper limb action tremor accompani...
Paroxysmal abdominalgia as a non-motor wearing off phenomenon in Parkinson's disease. A case series and literature review [0.03%]
帕金森病阵发性腹痛作为非运动性开关现象的病例系列和文献综述
Abdalmalik Bin Khunayfir,Stewart A Factor
Abdalmalik Bin Khunayfir
Background: Paroxysmal abdominalgia (PxA) is an underrecognized, debilitating form of abdominal pain that manifests during wearing-off (WO) periods in Parkinson's disease (PD). Despite its profound impact, PxA remains poo...
Impact of dance/music and meditation on the progression of Parkinson's disease with mild/ moderate severity: a single-blinded randomized controlled pilot study [0.03%]
舞蹈/音乐和冥想对轻中度帕金森病进展影响的单盲随机对照试点研究
Paresh K Doshi,Bhagyashree Mehrotra,Neha Rai et al.
Paresh K Doshi et al.
Background: Parkinson's disease (PD) significantly impairs motor and cognitive functions, reducing quality of life. Non-pharmacological interventions, such as dance/music therapy combined with meditation, may offer potent...