Safety and Feasibility of Serial Lumbar Punctures: Long-term Results from the Parkinson's Progression Markers Initiative [0.03%]
重复腰椎穿刺的安全性和可行性——来自帕金森病进展标记物计划的长期结果分析
William Barbosa,Ruth B Schneider,Seung Ho Choi et al.
William Barbosa et al.
Background: Cerebrospinal fluid (CSF) serves an essential role in biomarker research. New Parkinson's disease (PD) classifications incorporate CSF α-synuclein status into trial design. This study evaluated the safety and...
Validation of the English version of the Parkinson Anxiety Scale in two Canadian Parkinson's disease samples [0.03%]
帕金森病焦虑量表英文版在加拿大两个样本中的验证研究
Joyce S T Lam,Kira N Tosefsky,Xuyan Tang et al.
Joyce S T Lam et al.
Introduction: The 12-item Parkinson Anxiety Scale (PAS) assesses the severity of anxiety symptoms in people with Parkinson's disease (PwP). However, psychometric evidence supporting the English self-rated PAS remains larg...
Advance care planning in Hispanic populations with Parkinson's Disease: Investigating disparities in end-of life care [0.03%]
帕金森病患者的希伯来人人口中的预先护理计划：调查生命末期护理的差异性问题
Taylor Peabody,Monica Abou-Ezzi,Lucila Hernandez et al.
Taylor Peabody et al.
Introduction: Advance care planning (ACP) is a tool for optimizing end-of-life care and is an important aspect of healthcare for people with Parkinson's disease (PD). However, there may be disparities in access to ACP bas...
Diagnostic analysis of adult neuronal ceroid lipofuscinosis caused by CLN6 gene mutation: a case report [0.03%]
CLN6基因突变所致成人神经元脑脂褐症的诊断分析1例报告
Yubo Hu,Haochen Sun,Qin Jiang et al.
Yubo Hu et al.
Neuronal ceroid lipofuscinosis is a rare lysosomal storage disorder that is difficult to distinguish from other diseases with similar clinical symptoms in its early stages. This article analyzes and summarizes the diagnostic process of a fa...
Beyond the needle: how clinician expertise affects outcomes in the treatment of hemifacial spasm [0.03%]
超越针刺：临床医师的专长如何影响半面痉挛治疗效果
Melissa Luque-Llano,Maria Angelica-Coronel,Yulexy T Alvarado-Vanegas et al.
Melissa Luque-Llano et al.
Background: Hemifacial spasm (HFS) is characterized by abnormal contraction of the muscles innervated by the seventh cranial nerve. It is usually benign and diagnosed clinically. The effectiveness of botulinum toxin (BoNT...
Peng Li-Hua,Lamarana Jallow,Yurong Tan et al.
Peng Li-Hua et al.
Background: Parkinson's disease (PD) is a complex neurodegenerative disorder requiring multidimensional treatment approaches. Recent breakthroughs in precision medicine and growing evidence for music therapy efficacy present new opportuniti...
The impact of pregabalin and gabapentin on essential tremor: a systematic review and meta-analysis [0.03%]
普瑞巴林和加巴喷丁对原发性震颤影响的系统评价和meta分析
Hooman Pourbala,Zhale Nahavandi,Arash Maghsoudlou et al.
Hooman Pourbala et al.
Introduction: Essential tremor (ET) is a common neurological disorder characterized by involuntary rhythmic oscillations. Emerging evidence suggests that gabapentinoids, including gabapentin and pregabalin, may be effecti...
Usability, safety and tolerability of CUE1 vibrotactile device as promising therapeutic approach in orthostatic tremor [0.03%]
用于直立性震颤治疗的CUE1振动触觉装置的有效性、安全性和耐受性研究
Viktoria Azoidou,Alexandra Zirra,Thomas Boyle et al.
Viktoria Azoidou et al.
Introduction: Primary Orthostatic Tremor (POT) is a rare hyperkinetic movement disorder characterized by unsteadiness while standing, often exacerbated by anxiety and fatigue. It significantly impairs quality of life, and...
Verbal fluency is associated with Gait impairment in Progressive Supranuclear Palsy [0.03%]
进行性核上性麻痹患者流畅度与步态障碍的关系
Aminette D&#x;Souza,Charalampos Sotirakis,Niall Conway et al.
Aminette D&#x;Souza et al.
Introduction: Gait impairment is an important diagnostic criterion for Progressive Supranuclear Palsy (PSP) and may be modulated by specific cognitive domains such as executive function. This study aims to investigate the...
How to dose extended-release carbidopa-levodopa capsules (IPX203, CREXONT®) in patients with Parkinson's disease [0.03%]
如何在帕金森病患者中使用卡比多巴-左旋多巴缓释胶囊（IPX203，CREXONT®）
Robert A Hauser,Yasar Torres-Yaghi,Stanley Fisher et al.
Robert A Hauser et al.
IPX203 (CREXONT®) is a novel, oral, extended-release (ER) carbidopa-levodopa (CD-LD) formulation, designed to rapidly achieve LD plasma concentrations similar to immediate-release (IR) CD-LD and to maintain LD concentrations for a longer d...