Correlation analyses between MIBG myocardial scintigraphy and monoamine levels in dementia with Lewy bodies show potential link with the serotonergic system [0.03%]
MIBG心肌显像与Lewy体痴呆单胺水平的相关分析显示其可能与五羟色胺能系统有关
Annelies Heylen,Yannick Vermeiren,Sebastiaan Engelborghs et al.
Annelies Heylen et al.
Setting: Dementia with Lewy bodies (DLB) remains poorly understood and frequently misdiagnosed, complicated by co-pathology with other dementia forms. DLB patients often present with autonomic dysfunction and peripheral L...
Differences between patient- and therapist-rated working alliance and their relationships with physical rehabilitation outcomes in individuals with Parkinson's disease [0.03%]
帕金森病患者的康复治疗联盟：患者报告与治疗师报告的差异及其对物理康复效果的影响
Keita Sue,Kazumi Sakurai,Daiki Usuda et al.
Keita Sue et al.
Introduction: Working Alliance (WA) significantly influences therapeutic success in psychotherapy or rehabilitation for musculoskeletal problems. The perception of WA often differs between patients and therapists. However...
Movement disorders accompanying lithium intoxication - An evolving clinical presentation and SILENT syndrome [0.03%]
锂中毒伴发的运动障碍及隐匿性锂中毒综合征临床表现分析
Artur Bystrzyński,Magdalena Kwaśniak-Butowska,Jarosław Sławek
Artur Bystrzyński
Lithium carbonate is a known medication for bipolar disorder and requires monitoring due to the central nervous system toxicity. Symptoms mainly include cerebellar dysfunction, although may fluctuate and change over time. We present an evol...
Opicapone improves end-of-dose neuropsychiatric fluctuations in patients with Parkinson's disease [0.03%]
恩他卡朋改善帕金森病患者的剂末神经精神症状波动作用
Roberta De Fiores,Iolanda Martino,Andrea Quattrone et al.
Roberta De Fiores et al.
Introduction: Non-motor fluctuations (NMF) represent one of the main complications that patients with Parkinson's disease (PD) may experience during long-term levodopa treatment. Opicapone (OPC), a COMT-inhibitor indicate...
Sedation and sleep safety of pimavanserin for Parkinsons's disease psychosis: Review and exploratory analysis of clinical study data [0.03%]
用于帕金森病精神病的普拉克索镇静和睡眠安全性的综述及临床数据分析探索性分析
Ana Berrio,Lambros Chrones,Victor Abler et al.
Ana Berrio et al.
Patients with Parkinson's disease almost uniformly experience sleep disorders. Sleep disorders have been linked to the severity of cognitive impairment, which is also a comorbidity with Parkinson's disease psychosis (PDP). Pimavanserin, a h...
Leukoaraiosis does not impact motor outcomes in Parkinson's patients post deep brain stimulation [0.03%]
白质高信号不影响帕金森病患者术后运动结果
Heather Martin,Rushna Ali,Ashok Sriram et al.
Heather Martin et al.
Objectives: We sought to assess the impact of leukoaraiosis (LA) on motor outcomes in Parkinson disease (PD) patients undergoing DBS. We hypothesized that LA is associated with less improvement in motor function in PD pat...
Expectations regarding regenerative medicine and attitudes toward invasive surgical therapies in patients with Parkinson's disease: A cross-sectional survey [0.03%]
帕金森病患者的再生医学期望及其对侵入性手术治疗的态度：横断面调查结果
Mika Watabe,Atsushi Shima,Kiyoaki Takeda et al.
Mika Watabe et al.
Introduction: Pharmacological control of the motor symptoms of Parkinson's disease (PD) is challenging with disease progression. Device-aided therapies help relieve these symptoms but are invasive and require specific man...
Quality Measure Adherence in Parkinson's Disease: A Single Center Experience***Parkinson's Disease Quality Measures [0.03%]
帕金森病质量措施依从性：单一中心经验
Tanner Bradford,Bryanna De Lima,Kahley Milauskas et al.
Tanner Bradford et al.
Background: Patients with Parkinson's Disease (PWPs) often have both motor and non-motor manifestations requiring specialized care. Neurologists typically lead their care; however, the population of PWPs is exceeding the ...
An unusual presentation of Huntington's disease-like syndrome in a patient with Xeroderma pigmentosum type F: Case report and review of the literature [0.03%]
Xeroderma Pigmentosum组F型合并Huntington舞蹈病样综合征一例及文献复习
Nicolas De Cleene,Federico Carbone,Clancy Cerejo et al.
Nicolas De Cleene et al.
Background: Xeroderma pigmentosum (XP) is a rare genetic disease in which the Nucleotide Excision Repair (NER) system is affected, resulting in defective DNA-repair. Clinical features are UV-light hypersensitivity with er...
The most common structural variant expected at the GBA1 locus may be detected by a simple amplification method: Implications for screening Parkinson's disease variants [0.03%]
GBA1位点最常见结构变异可通过简单的扩增方法检测到：筛查帕金森病突变的启示
Roberto Rozenberg,Fabiano Tofoli de Araujo,Hsin Fen Chien et al.
Roberto Rozenberg et al.
Introduction: Recombinant alleles are responsible for a large part of Gaucher disease (GD) causing alterations. This is because GBA1, the gene involved in GD, has a 96 % homologous pseudogene, GBAP1, at a 1.6kb distance. ...