Expectations regarding regenerative medicine and attitudes toward invasive surgical therapies in patients with Parkinson's disease: A cross-sectional survey [0.03%]
帕金森病患者的再生医学期望及其对侵入性手术治疗的态度：横断面调查结果
Mika Watabe,Atsushi Shima,Kiyoaki Takeda et al.
Mika Watabe et al.
Introduction: Pharmacological control of the motor symptoms of Parkinson's disease (PD) is challenging with disease progression. Device-aided therapies help relieve these symptoms but are invasive and require specific man...
Quality Measure Adherence in Parkinson's Disease: A Single Center Experience***Parkinson's Disease Quality Measures [0.03%]
帕金森病质量措施依从性：单一中心经验
Tanner Bradford,Bryanna De Lima,Kahley Milauskas et al.
Tanner Bradford et al.
Background: Patients with Parkinson's Disease (PWPs) often have both motor and non-motor manifestations requiring specialized care. Neurologists typically lead their care; however, the population of PWPs is exceeding the ...
An unusual presentation of Huntington's disease-like syndrome in a patient with Xeroderma pigmentosum type F: Case report and review of the literature [0.03%]
Xeroderma Pigmentosum组F型合并Huntington舞蹈病样综合征一例及文献复习
Nicolas De Cleene,Federico Carbone,Clancy Cerejo et al.
Nicolas De Cleene et al.
Background: Xeroderma pigmentosum (XP) is a rare genetic disease in which the Nucleotide Excision Repair (NER) system is affected, resulting in defective DNA-repair. Clinical features are UV-light hypersensitivity with er...
The most common structural variant expected at the GBA1 locus may be detected by a simple amplification method: Implications for screening Parkinson's disease variants [0.03%]
GBA1位点最常见结构变异可通过简单的扩增方法检测到：筛查帕金森病突变的启示
Roberto Rozenberg,Fabiano Tofoli de Araujo,Hsin Fen Chien et al.
Roberto Rozenberg et al.
Introduction: Recombinant alleles are responsible for a large part of Gaucher disease (GD) causing alterations. This is because GBA1, the gene involved in GD, has a 96 % homologous pseudogene, GBAP1, at a 1.6kb distance. ...
Understanding personal preferences to promote exercise adherence in Parkinson's disease [0.03%]
了解帕金森病患者运动锻炼的个人偏好以提高其依从性
Caro I Cools,Sonja A Kotz,Bastiaan R Bloem et al.
Caro I Cools et al.
Introduction: Exercise is a recognized treatment for people with Parkinson's Disease (PwP), but personal exercise preferences are rarely considered in exercise intervention studies. Yet these are critical for understandin...
Significant relief of parkinsonism and dystonia with levodopa in beta-propeller protein-associated neurodegeneration: a video case report and insights into the WDR45 c.400C>T mutation [0.03%]
β- Propeller 蛋白相关神经退行性疾病帕金森病和肌张力障碍症状与左旋多巴的治疗：一段视频病例报道及c. 400 C> T突变研究见解
Wen-Che Li,Pou-Leng Cheong,Kai-Hsiang Stanley Chen
Wen-Che Li
We describe a young woman with BPAN carrying c.400 C>T mutation in WDR45. Her motor symptoms improved with low-dose levodopa. Notably, the absence of seizures in adulthood and Rett-like features in our patient, consistent with previous repo...
Post hoc exploratory analysis of the effect of foslevodopa/foscarbidopa continuous subcutaneous infusion on nocturia in patients with Parkinson's disease [0.03%]
帕金森病患者服用左旋多巴/卡比多巴连续皮下输注对夜尿影响的探索性分析
K Ray Chaudhuri,Manon Bouchard,Eric Freire-Alvarez et al.
K Ray Chaudhuri et al.
Introduction: Parkinson's disease (PD) non-motor symptom burden, including nocturia and sleep disturbances, worsens with disease progression. Continuous dopaminergic drug delivery with nocturnal infusion in PD demonstrate...
Effects of augmented reality cueing strategies on freezing of gait: The ELIMINATE FoG trial [0.03%]
增强现实提示策略对步态冻结的影响：ELIMINATE FoG试验
Brendan Baugher,Ryan Kaya,Claire Sonneborn et al.
Brendan Baugher et al.
Background: Freezing of gait (FoG) is a treatment-resistant symptom of Parkinson disease (PD). Augmented reality (AR) cues have been investigated as a therapy for FoG, with inconclusive results from a limited array of AR ...
Long-term infective complications of deep brain stimulation in Parkinson's disease: A 22-year follow-up [0.03%]
帕金森病深部脑刺激长期感染并发症：一项22年的随访研究
Riccardo Antonio Ricciuti,Matteo Maria Ottaviani,Fabrizio Mancini et al.
Riccardo Antonio Ricciuti et al.
Introduction: Deep brain stimulation (DBS) is an established treatment for Parkinson's disease (PD), but infections remain a significant concern. This study evaluated infection rates and their impact in PD patients who un...
Nocturnal polyuria is common in Parkinson's and is associated with orthostatic hypotension [0.03%]
帕金森病夜间多尿症的患病率较高并伴有直立性低血压
Matthew D Smith,Anisha Cullen,Gabriella E Portlock et al.
Matthew D Smith et al.
Background: Nocturia is the most common lower urinary tract symptom (LUTS) in Parkinson's disease (PD) and impacts sleep and subsequent daytime function. Often nocturia in PD is attributed to overactive bladder, however w...