Sex Differences in Associations Between Measures of Hemodialysis Adequacy and Quality, Cardiovascular Outcomes, and Mortality: A Systematic Review [0.03%]
透析充分性指标与心血管结局及死亡率之间关联的性别差异：系统综述
Victoria J Riehl-Tonn,David D M Nicholl,Paul E Ronksley et al.
Victoria J Riehl-Tonn et al.
Rationale & objective: The female survival advantage is diminished with hemodialysis. We evaluated the associations between measures of hemodialysis adequacy and quality and cardiovascular outcomes and mortality by sex. ...
Multinational Real-World Practice Patterns in the Use of Antithrombotic Therapy Among Patients on Hemodialysis and Peritoneal Dialysis [0.03%]
透析患者的抗凝治疗多国真实世界实践模式研究
Murilo Guedes,Calvin Andrews,Junhui Zhao et al.
Murilo Guedes et al.
Rationale & objective: Patients with kidney failure requiring maintenance dialysis have a high risk of cardiovascular events warranting antithrombotic therapies, including oral anticoagulant (OAC) or antiplatelet therapy ...
Efficacy of Low-Dose Tolvaptan for Treatment of Profound Hyponatremia in Syndrome of Inappropriate Antidiuresis (SIAD): The EFFLUX-FLUID TRIAL [0.03%]
小剂量托伐普烷治疗尿崩症(SIADH)所致严重低钠血症的疗效：EFFLUX-FLUID试验
Narongchai Jaiyen,Sutatip Chinpraditsuk,Pattharawin Pattharanitima et al.
Narongchai Jaiyen et al.
Rationale & objective: Although tolvaptan is effective for treating hyponatremia in the syndrome of inappropriate antidiuresis (SIAD), fluid restriction remains the first-line therapy because of safety concerns. This stud...
Uptake of Newly Licensed Influenza Vaccine Formulations Among Patients Receiving Chronic Hemodialysis During the 2010/2011 to 2021/2022 Influenza Seasons [0.03%]
2010/2011至2021/2022流感季期间，慢性血液透析患者中新上市流感疫苗的使用情况
John M Sahrmann,J Bradley Layton,Katelin B Nickel et al.
John M Sahrmann et al.
B-Cell Depletion in Glomerular Diseases: Not Always as Safe as We May Think [0.03%]
论点：论B细胞耗竭在肾小球疾病中可能并非总是安全的
Decimo Silvio Chiarenza,Enrico E Verrina,Carolina Bigatti et al.
Decimo Silvio Chiarenza et al.
B-cell depletion with the chimeric anti-CD20 monoclonal antibody rituximab has revolutionized the treatment of glomerular diseases. Obinutuzumab, a type II glycoengineered anti-CD20 humanized monoclonal antibody, is increasingly being emplo...
Case Reports
Kidney medicine. 2026 Jan 14;8(3):101268. DOI:10.1016/j.xkme.2026.101268 2026
A Large Deletion With a Large Impact: Homozygous 5,600 bp Deletion of the GALNT3 Gene Causing Hyperphosphatemic Tumoral Calcinosis [0.03%]
一个大片段的基因缺失导致的一种罕见遗传病：GALNT3 基因5600bp片段纯合子缺失导致高磷血症性肿瘤样钙化症
Julia Maria Portmann,Katharina Martini,Angela Bahr et al.
Julia Maria Portmann et al.
Hyperphosphatemic familial tumoral calcinosis (HTC) is a rare disease caused by autosomal recessive loss of function variants in the genes encoding fibroblast growth factor 23 (FGF-23), Klotho, or GalNAc-T3. This results in reduced phosphat...
Case Reports
Kidney medicine. 2026 Jan 6;8(3):101241. DOI:10.1016/j.xkme.2026.101241 2026
Determining Physical Function Measures for Estimating VO2Peak in Patients Receiving Hemodialysis [0.03%]
透析患者估算VO2PEAK的生理功能指标确定
Nolan W Groninger,Monique Campos,Eliott Arroyo et al.
Nolan W Groninger et al.
Rationale & objective: Cardiopulmonary exercise testing is the gold standard for evaluating cardiovascular functional capacity, as assessed by oxygen uptake at peak exercise (VO2Peak). Traditional physical function tests ...
Samuel Ford,Ian Coombes,Julian Williams et al.
Samuel Ford et al.
Insulin-dextrose therapy is widely used to manage hyperkalemia but carries a significant risk of iatrogenic hypoglycemia. Glucose alone may reduce serum potassium by stimulating endogenous insulin release, potentially offering an insulin sp...
Steven Fishbane,Pratap Upadrista,Hitesh H Shah
Steven Fishbane
Composite study endpoints have made it possible to reduce the sample size and lower the cost of certain clinical trials. In nephrology trials, the use of composite endpoints has led to opportunities but has also created challenges in the in...
Mitochondrial DNA Analysis Should Be Considered in the Genetic Assessment of Focal Segmental Glomerulosclerosis or Unexplained Chronic Kidney Disease: A Case Report [0.03%]
线粒体DNA分析应纳入局灶节段性肾小球硬化或慢性不明原因肾病的基因评估中：案例报告
Chloe Borden,Iman Chaudhry,Rhyan Maditz et al.
Chloe Borden et al.
Genetic testing is increasingly used to assist the precise diagnosis and clinical management of suspected genetic kidney diseases; however, mitochondrial DNA (mtDNA) analysis remains underutilized. Here we report a 61-year-old man who prese...
Case Reports
Kidney medicine. 2025 Dec 24;8(3):101233. DOI:10.1016/j.xkme.2025.101233 2025