Wangyue Xu,Yue Teng,Sijie Zhou
Wangyue Xu
With the rapid advance in synthetic biology and the expanding field of synthetic genomics, the realization of a redesigned yeast genome has become an achievable milestone. Multiple eukaryotic chromosomes, meticulously designed and synthesiz...
Development and evaluation of a quadruple real-time fluorescence-based quantitative reverse transcription polymerase chain reaction assay for detecting Langya, Mojiang, Nipah, and Cedar viruses [0.03%]
四重实时荧光定量逆转录PCR检测Langya、Mojiang、Nipah和Cedar病毒的开发与评估
Wenjun He,Tian Ma,Yalan Wang et al.
Wenjun He et al.
The emerging viruses within the genus Henipavirus in the family Paramyxoviridae pose a great threat to public biosafety. To develop a quadruple real-time fluorescence-based quantitative reverse transcription polymerase chain reaction (qRT-P...
Zhenchao Zhou,Hong Chen
Zhenchao Zhou
Antibiotic resistance is an escalating global concern, leading to millions of annual fatalities. Antibiotic resistance genes (ARGs) present in bacteria equip them to withstand the effects of antibiotics. Intra- and interspecific ARGs transm...
Prevalence of bacteria, fungi, and virus coinfections with SARS-CoV-2 Omicron variant among patients with severe COVID-19 in Guangzhou, China, winter 2022 [0.03%]
2022年冬季中国广州重症COVID-19患者中SARS-CoV-2奥米克戎变异株与细菌、真菌和病毒共感染的流行率
Qinghong Fan,Mengling Jiang,Jun Zhang et al.
Qinghong Fan et al.
The status of coinfection during the national outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.5.2 or BF.7 in China in the winter of 2022, which is suspected to contribute substantially to the overloaded s...
Construction of a bivalent vaccine candidate against HAdV4/HAdV7 based on capsid-display strategy via Red-homologous recombination and counter-selection methodology [0.03%]
基于衣壳展示策略通过Red同源重组及反向选择方法构建HAdV4/HAdV7双价候选疫苗
Peng Wang,Yunting Shao,Xichun Yang et al.
Peng Wang et al.
Human adenoviruses (HAdVs) are major respiratory pathogens. Specifically, human adenovirus type 4 (HAdV4) and human adenovirus type 7 (HAdV7) are known for causing fever and pneumonia, with documented cases of fatalities among the populatio...
Epidemiology and genetic characterization of tet(X4)-positive Klebsiella pneumoniae and Klebsiella quasipneumoniae isolated from raw meat in Chengdu City, China [0.03%]
中国成都市生肉中分离出的携带tet(X4)的肺炎克雷伯菌和准肺炎克雷伯菌的流行病学及基因特征研究
Weishuai Zhai,Yiqing Wang,Honghu Sun et al.
Weishuai Zhai et al.
The rapid spread of mobile tigecycline resistance presents a significant public health threat, particularly with the increasing prevalence of tet(X4)-positive Enterobacterales across various species. This study aimed to investigate the epid...
Superior effectiveness and acceptability of saliva samples for the detection of SARS-CoV-2 in China [0.03%]
中国使用唾液样本检测SARS-CoV-2的优越效果和可接受性
Hui Yao,Ying Shen,Zhichao Liang et al.
Hui Yao et al.
In response to problems of poor sampling quality, low sensitivity, and high demand for medical personnel regarding the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) oropharyngeal (OP) swab sampling used in China, we a...
Yanan Wang,Mengqi Qu,Yuhai Bi et al.
Yanan Wang et al.
Chicken is an important food animal worldwide and plays an important role in human life by providing meat and eggs. Despite recent significant advances in gut microbiome studies, a comprehensive study of chicken gut bacterial, archaeal, and...
A One Health approach to fight antimicrobial resistance in Uganda: Implementation experience, results, and lessons learned [0.03%]
乌干达采用“同一健康”方法应对抗生素耐药性的实践、结果和经验教训
Reuben Kiggundu,J P Waswa,Niranjan Konduri et al.
Reuben Kiggundu et al.
Uganda has been implementing the Global Health Security Agenda (GHSA) since 2015 to build its capacity according to World Health Organization (WHO) Benchmarks on International Health Regulations Capacities. The country remains prone to outb...
Genomic surveillance of emerging SARS-CoV-2 Omicron variations in Tianjin Municipality, China 2022 [0.03%]
2022年中国天津市新兴SARS-CoV-2奥密克戎变异的基因组监测
Xin Gao,Ming Zou,Yue Lei et al.
Xin Gao et al.
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has severely impacted public health. In 2022, the Omicron variant of SARS-CoV-2 rapidly became the dominant circulating ...