Yilu Ye,Tingting Sun,Saisai Guo et al.
Yilu Ye et al.
Rab proteins are involved in all facets of the vesicular transport process and play significant roles in different steps of the viral life cycle. Rab4b is a pivotal player in the endocytic recycling of proteins, whereas its roles in viral r...
Shangzhe Li,Yue Shi,Jing Yang et al.
Shangzhe Li et al.
Deoxyribonucleic acid (DNA) information storage has emerged as a promising solution to address the challenges of traditional silicon-based data storage systems. However, the biosafety implications of artificially synthesized DNA sequences i...
Antigenicity and genetic properties of an Eurasian avian-like H1N1 swine influenza virus in Jiangsu Province, China [0.03%]
中国江苏省欧亚类禽H1N1流感病毒的抗原性和遗传特性研究
Fang He,Huiyan Yu,Liqi Liu et al.
Fang He et al.
Pigs are vital genetic mixing vessels for human and avian influenza viruses because their tracheal epitheliums possess both sialic acid α-2,6-Gal and α-2,3-Gal receptors. Cross-species transmission of influenza A viruses from swine to hum...
A comparative analysis of influenza and COVID-19: Environmental-ecological impacts, socioeconomic implications, and future challenges [0.03%]
流感和COVID-19的比较分析：环境生态影响、社会经济含义及未来挑战
Yongman Guo,Kuiying Gu,Paul A Garber et al.
Yongman Guo et al.
In the last century, global pandemics have been primarily driven by respiratory infections, which consistently rank among the top 20 causes of death worldwide. The coronavirus disease 2019 (COVID-19) pandemic has underscored the intricate n...
Rapidly quantification of intact infectious H1N1 virus using ICA-qPCR and PMA-qPCR [0.03%]
利用ICA-qPCR和PMA-qPCR快速量化完整的甲型H1N1病毒
Chudan Liang,Zequn Wang,Linjin Fan et al.
Chudan Liang et al.
The increase in emerging and reemerging infectious diseases has underscored the need for the prompt monitoring of intact infectious viruses and the quick assessment of their infectivity. However, molecular techniques cannot distinguish betw...
Molecular epidemiological study on tick-borne pathogens in Qinghai Province, Northwestern China [0.03%]
中国西北青海省蜱传病原体的分子流行病学研究
Chunfeng Luo,Yonghong Song,Luoyuan Xia et al.
Chunfeng Luo et al.
Recently, there has been a continuous stream of reports on emerging tick-borne pathogens affecting humans. Qinghai Province, located in the northweastern region, is one of China's major pastoral areas, providing a suitable environment for t...
Q fever diagnosed using metagenomic next-generation sequencing in Guangdong Province, China [0.03%]
中国广东省应用宏基因组下一代测序技术诊断Q热病
Ting Hu,Yuan Cheng,Jia Wan et al.
Ting Hu et al.
Q fever is a zoonotic disease caused by infection with Coxiella burnetii (C. burnetii). Due to its atypical symptoms and the absence of specific detection methods, Q fever is underdiagnosed commonly. Herein, we report a case of Q fever conf...
Rapid generation and characterization of recombinant HCoV-OC43-VR1558 infectious clones expressing reporter Renilla luciferase [0.03%]
快速生成和鉴定表达海肾荧光素酶报告基因的重组人冠状病毒HCoV-OC43-VR1558感染性克隆
Fei Ye,Na Wang,Qiongge Guan et al.
Fei Ye et al.
Viral infectious clones (ICs) serve as robust platforms for studying viral biology and screening antiviral agents using reverse genetics. However, the molecular profiles and complex limitations of human coronaviruses (HCoVs) pose a challeng...
Narciclasine inhibits vaccinia virus infection by activating the RhoA signaling pathway [0.03%]
Narciclasine通过激活RhoA信号通路抑制牛痘病毒的感染
Ting Xu,Zhengyang Pan,Xue Li et al.
Ting Xu et al.
In 2022, a sharp rise in global cases of mpox virus (MPXV) led the World Health Organization (WHO) to declare it a public health emergency of international concern. However, progress in developing drugs targeting MPXV has been slow. Here, w...