The prevalence and genetic characteristics of human bocavirus in patients with acute respiratory infection in China during 2012-2021 [0.03%]
2012-2021年中国急性呼吸道感染患者人博卡病毒流行现状及基因特征分析
Haoran Jiang,Baicheng Xia,Xujing Chi et al.
Haoran Jiang et al.
Human bocavirus (HBoV) is a common respiratory virus among patients with acute respiratory infection (ARI). To investigate the prevalence and genetic characteristics of HBoV, clinical specimens from 13,109 ARI patients were collected throug...
Spatiotemporal patterns and influencing factors of genotypic resistance testing utilization among people living with HIV: A 10-year retrospective analysis at a tertiary care hospital in Beijing, China (2014-2023) [0.03%]
中国北京一家三级护理医院2014-2023年HIV感染者的基因型耐药检测利用时空模式及影响因素：基于回顾性分析
Defu Yuan,Fei Zhao,Shanshan Liu et al.
Defu Yuan et al.
Prior research indicated low genotypic resistance testing (GRT) for human immunodeficiency virus (HIV) utilization in China due to partial cost coverage under national antiretroviral therapy policies, limited testing accessibility, and fina...
The holistic rehabilitation from acute severe fever with thrombocytopenia syndrome virus infection to 10 years after recovery: A cross-sectional study [0.03%]
急性严重发热伴血小板减少综合征病毒感染康复至康复后10年的全面康复状况：横断面研究
Min Li,Yalan Wang,Peiwen Qiao et al.
Min Li et al.
Acute viral infections may lead to long-term adverse health effects. Investigating the hematological and biochemical profiles during recovery can provide valuable insights into the prognosis of severe fever with thrombocytopenia syndrome (S...
Xinxin Li,Yuanjiao Gao,Ziyu Zhang et al.
Xinxin Li et al.
Since the discovery of the double helix structure of deoxyribonucleic acid (DNA), significant progress has been made in engineering technologies such as gene analysis and editing, greatly promoting the development of biomedical research and...
Longitudinal profiling of host response and oropharyngeal respiratory microbiome reveals dynamic alterations during recovery from community-acquired pneumonia [0.03%]
队列研究揭示了社区获得性肺炎的恢复过程中宿主反应和口咽部微生物群的动态变化
Lizhe Hong,Lijun Suo,Kang Chang et al.
Lizhe Hong et al.
Community-acquired pneumonia (CAP) is a major global health concern, with limited understanding of longitudinal changes in host gene expression and respiratory microbiome throughout disease progression and recovery. To address this gap, we ...
Detection of the mpox virus using a robust recombinase-aided amplification-based approach [0.03%]
一种基于重组酶介导的扩增方法检测猴痘病毒的新方案
Meihui Luo,Yuanchun Shan,Xin Zhang et al.
Meihui Luo et al.
In 2022, a global outbreak of mpox was anticipated, with several cases reported in non-endemic countries in early May. Given the challenge of distinguishing the mpox virus (MPXV) from other pathogens based solely on symptoms, there is an ur...
Detecting and classifying metabolic activity of Staphylococcus aureus by D2O-probed single-cell Raman spectroscopy and machine learning [0.03%]
利用D2O单细胞拉曼光谱和机器学习检测并分类金黄色葡萄球菌的代谢活性
Li Liu,Bing Feng,Yang Song et al.
Li Liu et al.
The metabolic activity of pathogens poses a substantial risk across diverse domains, including food safety, vaccine development, clinical treatment, and national biosecurity. Conventional subculturing methods typically require several days ...
Guowu Shen,Xiaohua Zhao,Jie Chen et al.
Guowu Shen et al.
Brucellosis poses a significant health threat to the population, particularly to vulnerable populations, including infants. In this investigation, we retrospectively analyzed the infection source and potential transmission route in a three-...
Longitudinal analysis of cytokine dynamics in severe fever with thrombocytopenia syndrome patients - High-incidence regions of China (2010-2023) [0.03%]
中国严重发热伴血小板减少综合征患者细胞因子动力学的纵向分析（2010-2023年高发区数据）
Yanhan Wen,Yeqing Tong,Lei Gong et al.
Yanhan Wen et al.
Severe fever with thrombocytopenia syndrome (SFTS) is a life-threatening tick-borne disease characterized by cytokine dysregulation and immune-mediated hyperinflammation. This multicenter retrospective study analyzed the dynamics of 17 cyto...
Development of an in-house dual RT-qPCR assay for detecting SFTSV and Hantaan virus simultaneously [0.03%]
一种检测发热伴血小板减少综合征病毒和汉坦病毒的双靶实时荧光定量RT-PCR方法研究
Xiaoyu Xue,Youde Liu,Chuan Song et al.
Xiaoyu Xue et al.
Given the overlapping endemic regions and clinical similarities between severe fever with thrombocytopenia syndrome (SFTS) and hemorrhagic fever with renal syndrome (HFRS), we developed a dual real-time fluorescence-based reverse transcript...