Predict SARS-CoV-2 genome interactions based on RNA language models [0.03%]
基于RNA语言模型预测SARS-CoV-2基因组相互作用
Weiwei Shen,Yixue Li,Liucun Zhu et al.
Weiwei Shen et al.
As a single-stranded ribonucleic acid (RNA) virus, the replication, transcription, and interactions with host cells of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) rely on a complex network of RNA-RNA interactions. Inves...
Inactivation of BSL-2 and BSL-3 human pathogens using FATHHOME's Trinion Disinfector: A rapid and eco-friendly ozone-based dry disinfection approach [0.03%]
利用FATHHOME的Trinion消毒器失活BSL-2和BSL-3人类病原体：一种快速且生态友好的基于臭氧的干式消毒方法
Kabita Adhikari,Elizabeth Zhou,Majid Khan et al.
Kabita Adhikari et al.
The role of personal protective equipment (PPE) in protecting against exposure to infectious agents and toxic chemicals is well-established. However, the global surge in PPE demand during the pandemic exposed challenges, including shortages...
A metagenomic approach for microbial risk assessment and source attribution in high-risk ports of entry environments [0.03%]
口岸高风险环境中的微生物风险评估与来源追溯的宏基因组方法
Xiaozhou He,Ran Zhang,Jie Dong et al.
Xiaozhou He et al.
The epidemiological characteristics of emerging infectious disease outbreaks in recent years have underscored the critical importance of controlling imported infectious diseases. In this study, we implemented dynamic tracking of microbial i...
Development of an identity test for COVID-19 mRNA vaccines using SARS-CoV-2 NAT standard [0.03%]
基于新冠病毒核酸检测标准品的COVID-19mRNA疫苗鉴别方法的研究与发展
Miran Jo,Eunjo Lee,Ho Jung Oh et al.
Miran Jo et al.
Despite the development of messenger ribonucleic acid (mRNA) vaccines for the infectious novel coronavirus 2 (SARS-CoV-2), further research on test methods is required to ensure their quality as well as rapid and effective approval for rele...
DeepHVI: A multimodal deep learning framework for predicting human-virus protein-protein interactions using protein language models [0.03%]
基于蛋白质语言模型预测人病毒互作的多模态深度学习框架
Xindi Wang,Junyu Luo,Xiyang Cai et al.
Xindi Wang et al.
Understanding human-virus protein-protein interactions is critical for studying molecular mechanisms driving viral infection, immune evasion, and propagation, thereby informing strategies for public health. Here, we introduce a novel multim...
Wanying Gao,Zongzhen Wu,Kunlan Zuo et al.
Wanying Gao et al.
Biosafety is essential to ensuring the safe and effective conduct of biological research by minimizing risks associated with laboratory work and biological materials. This paper traces the historical and conceptual development of biosafety,...
Random forest-based predictor selection and pneumonia risk probability assessment in acute respiratory infections: A cross-sectional study in Chongqing, China, 2023-2024 [0.03%]
基于随机森林的预测选择和急性呼吸道感染肺炎风险概率评估：中国重庆地区2023-2024年横断面研究
Yunshao Xu,Yuping Duan,Jule Yang et al.
Yunshao Xu et al.
Progression of acute respiratory infection (ARI) to pneumonia increases severity and healthcare burden. Limited evidence exists on using machine learning to identify predictors from demographics, clinical, and pathogen detection data. This ...
Microbiota of critical areas prior to reopening in an oncology center: Potential uncommon nosocomial pathogens for vulnerable populations [0.03%]
肿瘤科中心重新开放前关键区域的微生物群：潜在的不常见的医院获得性病原体及其易感人群
Freddy Villanueva-Cotrina,Fiorella Quiroz,Kathya L Mimbela et al.
Freddy Villanueva-Cotrina et al.
Healthcare-associated infections are linked with the contamination of inanimate surfaces and the air in occupied hospital areas by recognized pathogens. However, there is limited information about the presence of these microorganisms or oth...
IncRNA IPAN antagonizes RIG-I/TRIM25-mediated degradation of influenza A virus PB1 to promote viral replication [0.03%]
长链非编码RNA IPAN通过拮抗RIG-I/TRIM25介导的流感病毒PB1降解来促进病毒复制
Tingting Sun,Shumin Chen,Rui Zhou et al.
Tingting Sun et al.
The productive infection of influenza A virus (IAV) requires the functional involvement of host long noncoding ribonucleic acids (lncRNAs). Identification of key cellular lncRNAs and elucidation of their molecular mechanisms in IAV replicat...
Clinical prognostic value of TTV and HCMV but not EBV for outcomes in hospitalized HIV-positive patients [0.03%]
TTV和HCMV而非EBV可作为住院HIV阳性患者临床预后的标志物
Qinghong Fan,Guofang Tang,Mengling Jiang et al.
Qinghong Fan et al.
Opportunistic infections caused by viruses, bacteria, fungi, and parasites, are commonly reported in hospitalized human immunodeficiency virus (HIV)-positive patients, but their detrimental contribution to disease severity remains under exp...