SFTS exerts an underrecognized disease burden and socioeconomic effect in East Asia [0.03%]
发热伴血小板减少综合征在东亚地区疾病负担及经济社会影响不容忽视
Wen Zheng,Fang Zhong,Weixue Wang et al.
Wen Zheng et al.
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus that poses a growing public health concern, especially in East Asia. However, its global distribution, disease burden, and economic impact remain insu...
China's malaria elimination: One Health lessons for vector-borne disease governance [0.03%]
中国消除疟疾：“同一个健康”的经验教训及对媒介传播疾病的治理启示
Jianying Liu,Yang Liu,Gong Cheng
Jianying Liu
China's certification as malaria-free by the World Health Organization in 2021 marked the achievement of seven decades of adaptive surveillance, evolving strategies, and community engagement. The British Medical Journal series led by Qiyong...
SEC11A identified as a critical host factor for HMPV through virus-induced alternative splicing [0.03%]
HMPV诱导的替代剪接鉴定出宿主因子SEC11A
Yiman Huang,Jiayin Guo,Shiyuan Zheng et al.
Yiman Huang et al.
Alternative splicing (AS) significantly increases the diversity of the eukaryotic proteome, and alterations in AS induced by viruses have emerged as a novel approach to studying virus-host interactions. Human metapneumovirus (HMPV) interact...
Leveraging knowledge graphs and large language models for integrating molecular variants and clinical insights in COVID-19 research [0.03%]
利用知识图谱和大型语言模型整合分子变异和临床洞察以促进COVID-19研究
Jiaxin Yang,Fushuai Zhang,Ruifang Cao et al.
Jiaxin Yang et al.
The relentless emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants continues to challenge global health, as high mutation rates and complex pathogenicity obscure molecular mechanisms and impede clinical progre...
Seroepidemiological study of pertussis in Henan Province, China, and prediction of the effectiveness of a new immunization strategy [0.03%]
中国河南省百日咳血清流行病学研究及新的免疫策略有效性的预测分析
Yuting Tang,Qian Liu,Jiangnan Kong et al.
Yuting Tang et al.
The study objectives were to analyze the epidemiological characteristics of pertussis in Henan Province, China, and to evaluate the impact of pertussis vaccination strategy adjustments on population infection rates. A retrospective analysis...
The urban infection susceptibility index and its application in cities of China [0.03%]
我国城市传染性疾病易感性指数及其应用研究
Wei Yan,Jianping Huang,Xinbo Lian et al.
Wei Yan et al.
Infectious diseases pose a serious threat to human health and social safety. In order to better respond to large-scale outbreaks of infectious diseases in the context of climate change, it is essential to identify potential high-risk areas ...
Impact of adjuvants on a recombinant SARS-CoV-2 spike vaccine: Protective efficacy and recall antibody response following homologous challenge [0.03%]
辅助剂对重组新型冠状病毒(SARSCoV2)刺突疫苗的影响：同源攻击后的保护效力和召回抗体反应
Dawei Wang,Zhendong Pan,Liangliang Jiang et al.
Dawei Wang et al.
Immune imprinting, or original antigenic sin, challenges the control of evolving severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). How the quantity and quality of pre-existing immunity modulate the recall antibody response upon ...
Advances in the development of infectious clones of human coronaviruses and related applications [0.03%]
人冠状病毒感染性克隆的发展进展及相关的应用研究
Guanya Liu,Ruixiao Tan,Yiyi Wu et al.
Guanya Liu et al.
Coronaviruses can infect humans, mammals, and birds, leading to respiratory, gastrointestinal, and neurological diseases. These viruses are significant zoonotic pathogens with nine known types capable of infecting humans. The coronavirus ge...
Epidemiological characteristics of human adenovirus infections in China, 2020-2023 [0.03%]
中国2020—2023年人腺病毒疫情流行病学特征分析
Chongyang Li,Yitong Lin,Naiying Mao et al.
Chongyang Li et al.
To better understand the epidemiological characteristics of human adenovirus (HAdV) infections in China during and after the coronavirus disease 2019 (COVID-19) pandemic, respiratory specimens were collected from 17,562 enrolled patients wi...
Genomic characteristics of 12 HBV-I strains in the 2020 national HBV serosurvey in China [0.03%]
2020年中国乙肝血清流行病学HBV—I型基因特征分析
Qiudong Su,Liping Shen,Xiaoqi Guo et al.
Qiudong Su et al.
Hepatitis B virus (HBV) is categorized into ten distinct genotypes (A - J), with over 40 subgenotypes identified to date. HBV genotype I (HBV-I), an inter-genotypic recombinant, has emerged during the evolution history of HBV. In this study...