Efficient reporting delay calibration in spatial metapopulation models for reconstructing cross-regional epidemic dynamics [0.03%]
高效校准空间元种群模型中的报告延迟以重建区域间流行病动态
Huichun Li,Yue Teng,Zhenghu Zu et al.
Huichun Li et al.
Reconstructing the early spatiotemporal dynamics of emerging infectious diseases (EIDs) is essential for effective public health response but remains difficult due to reporting delays, heterogeneous surveillance systems, and cryptic transmi...
Development of monoclonal antibody-based methods for detecting mpox virus [0.03%]
用于检测猴痘病毒的单克隆抗体方法的研发
Zuoyuan Du,Xingqi Wu,Li Guo et al.
Zuoyuan Du et al.
The World Health Organization declared mpox a public health emergency of international concern in both 2022 and 2024, highlighting the critical need for rapid and reliable diagnostic solutions. To address this challenge, we developed monocl...
A rapid and sensitive yellow fever virus detection method based on CRISPR/Cas13a and reverse transcription recombinase-aided amplification with special lateral-flow test strips [0.03%]
一种基于CRISPR/Cas13a和反转录重组酶扩增的快速灵敏的黄热病毒检出方法及特异试纸条检测
Yujie Yan,Tong Wei,Xue Dong et al.
Yujie Yan et al.
Yellow fever (YF) is an epidemic disease caused by the yellow fever virus (YFV). Historically, it has caused several epidemics and continues to result in fatalities in South Sudan and other regions today. Due to its limited therapeutic opti...
Shifting seasonal patterns of influenza before, during, and after the COVID-19 pandemic in Shanghai, China: A population-based surveillance study, 2015-2023 [0.03%]
中国上海在2015年至2023年间COVID-19大流行前、期间和之后流感季节性变化的模式：基于人群的监测研究
Yaxu Zheng,Yinzi Chen,Shenghua Mao et al.
Yaxu Zheng et al.
Seasonal influenza activity was disrupted due to the emergence of coronavirus disease 2019 (COVID-19) and the implementation of non-pharmaceutical interventions. In this study, we analyzed weekly influenza-like illness (ILI) cases and influ...
MTB-ImmunogenKG: An LLM-assisted knowledge graph for antigen selection in tuberculosis vaccine research [0.03%]
MTB-ImmunogenKG：一种LLM辅助的知识图谱，用于结核病疫苗研究中的抗原选择
Jielong Peng,Xinhao Zhuang,Yingying Chen et al.
Jielong Peng et al.
Tuberculosis (TB) vaccine design relies on the selection of optimal antigens. However, evidence on candidate antigens is scattered across the literature and rarely linked to critical vaccine parameters, such as immune responses, antigen com...
Beyond antibiotics: Multidimensional interventions and coordinated governance against ESKAPE resistance [0.03%]
超越抗生素：应对ESKAPE耐药性的多维度干预和协调治理
Guzhen Cui,Xinxin Wang,Wei Hong et al.
Guzhen Cui et al.
ESKAPE, including Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. pose a significant global health threat due to their extensive drug resistance and ...
A landscape of epidemiology and strain distribution of Nocardia in China [0.03%]
中国诺卡菌病的流行病学和血清型分布概况
Ziyu Song,Bingqian Du,Deming Tang et al.
Ziyu Song et al.
Nocardiosis is an uncommon infection that can cause severe damage or be life-threatening. However, the epidemiology and strain distribution of nocardiosis in China remain poorly characterized. In this study, a comprehensive literature searc...
Danyang Li,Zuoyuan Du,Qiao Zhang et al.
Danyang Li et al.
Since the 2022 global mpox outbreak, the lack of specific antibodies for mpox virus (MPXV) detection has hindered precise immunoassays due to cross-reactivity among Orthopoxviruses (OPXVs). This study developed and characterized two monoclo...
A semi-mechanistic modeling strategy for infectious diseases forecasting: Error correction and probabilistic prediction [0.03%]
一种传染病预测的半机制建模策略：误差修正和概率预测
Zihan Hao,Jiaxuan Hu,Shujuan Hu et al.
Zihan Hao et al.
Global climate change and technological advancements have intensified the threats of pandemics, while complex transmission dynamics challenge infectious disease forecasting. Traditional compartmental models struggle to fully capture both th...
Containment of antimicrobial resistance for strengthening global public health security: Biorisk management perspectives [0.03%]
防控抗微生物药物耐药性以加强全球公共卫生安全：生物风险管理视角
Md Asadulghani,Natasha K Griffith,William Arndt
Md Asadulghani
Antimicrobials have been hugely successful in improving health outcomes. However, its positive impact is threatened by worldwide increase of antimicrobial resistance (AMR). Use, misuse and overuse are the drivers of AMR. Antimicrobials are ...