A novel method to assess antibody-dependent cell-mediated cytotoxicity against influenza A virus M2 in immunized murine models [0.03%]
评估免疫小鼠模型中抗流感病毒M2抗体依赖性细胞介导的细胞毒性的新方法
Yinjie Liang,Junjia Guo,Zhen Li et al.
Yinjie Liang et al.
The matrix protein 2 (M2) is a preferred target for developing a universal vaccine against the influenza A virus (IAV). This study aimed to develop a method for assessing antibody-dependent cell-mediated cytotoxicity (ADCC) associated with ...
Human mpox co-infection with advanced HIV-1 and XDR-TB in a MSM patient previously vaccinated against smallpox: A case report [0.03%]
既往接种过天花疫苗的男男性行为者中HIV-1和广泛耐药结核病合并人猴痘感染一例报告
Yuan Fang,Fuchun Wang,Taiyi Jiang et al.
Yuan Fang et al.
Mpox is a zoonotic infectious disease caused by the mpox virus (MPXV). Historically, the majority of mpox cases have been documented in Central Africa. However, since May 2022, there has been a notable rise in reported cases from regions be...
Caspase-8 activation regulates enterovirus D68 infection-induced inflammatory response and cell death [0.03%]
半胱天冬酶-8的激活调节肠道病毒D68感染诱导的炎症反应和细胞死亡
Yuanyuan Zhou,Chongtao Zhang,Yuhan Zhang et al.
Yuanyuan Zhou et al.
Enterovirus D68 (EV-D68) infection causes severe acute respiratory infection and severe neurological complications, such as acute flaccid myelitis (AFM), in children. However, although EV-D68 has pandemic potential, no effective drugs or va...
A novel method for identifying SARS-CoV-2 infection mutants via an epitope-specific CD8+ T cell test [0.03%]
通过抗原表位特异性CD8+T细胞检测鉴定SARS-CoV-2感染突变株的新方法
Congling Qiu,Bo Peng,Chanchan Xiao et al.
Congling Qiu et al.
Since the outbreak of the coronavirus disease 2019 (COVID-19) epidemic in 2019, the public health system has faced enormous challenges. Tracking the individuals who test positive for severe acute respiratory syndrome coronavirus 2 (SARS-CoV...
Advances in technology for the laboratory diagnosis of individuals with HIV/AIDS coinfected with Mycobacterium tuberculosis [0.03%]
人类免疫缺陷病毒/艾滋病合并结核分枝杆菌感染的实验室诊断技术的进步
Jin Sun,Xiaoxu Han,Hongxia Yan et al.
Jin Sun et al.
The high morbidity and mortality rate of individuals with human immunodeficiency virus (HIV) / acquired immunodeficiency syndrome (AIDS) coinfected with Mycobacterium tuberculosis (MTB) is a tough challenge for current global tuberculosis p...
The differential effects of integrase strand transfer inhibitors and efavirenz on neuropsychiatric conditions and brain imaging in HIV-positive men who have sex with men [0.03%]
整合酶链转移抑制剂和依法韦伦对男男性行为的HIV阳性男子神经精神状况和脑成像的不同影响
Yihui He,Yang Zhang,Jiaxin Zhen et al.
Yihui He et al.
Integrase strand transfer inhibitors (INSTIs) have emerged as the first-line choice for treating human immunodeficiency virus (HIV) infection due to their superior efficacy and safety. However, the impact of INSTIs on the development of neu...
Automated robot and artificial intelligence-powered wastewater surveillance for proactive mpox outbreak prediction [0.03%]
用于主动预测猴痘疫情的自动化机器人和人工智能驱动的废水监测系统
Guanyong Ou,Yuxuan Tang,Jiexiang Liu et al.
Guanyong Ou et al.
In the wake of the largest-ever recorded outbreak of mpox in terms of magnitude and geographical spread in human history since May 2022, we innovatively developed an automated online sewage virus enrichment and concentration robot for disea...
A secure visualization platform for pathogenic genome analysis with an accurate reference database [0.03%]
具有精确参考数据库的病原体基因组分析的安全可视化平台
Guomei Fan,Chongye Guo,Qian Zhang et al.
Guomei Fan et al.
Investigating the genetic and developmental characteristics, infection transmission attributes, and epidemiological trends of pathogens using genomic data represents the foundation for pathogen surveillance and is a crucial prerequisite for...
Establishment of the benchmarking tool for evaluating the operation of biorepositories for pathogenic resource using a modified Delphi method [0.03%]
基于改进的Delphi方法建立评估病原资源生物样本库运行基准工具
Geng Hong,Dongxin Liu,Yuanyuan Zhao et al.
Geng Hong et al.
In recent years, as the infectious diseases caused by pathogens such as novel coronavirus and mpox (formerly called monkeypox) spread globally, the significance of identification, preservation, and sharing of pathogenic resources become pro...
Tuoyu Liu,Sijie Zhou,Tao Wang et al.
Tuoyu Liu et al.
Synthetic biology is a crucial component of the "cyber-biological revolution" in this new industrial revolution. Owing to breakthroughs in synthetic biology, deoxyribonucleic acid (DNA), the storehouse of hereditary material in biological s...