Full genomic sequence characterization of the chikungunya virus from an imported case with serum viral concentration below culturable level [0.03%]
基孔肯雅热病毒完整基因序列特征分析——来源于血清病毒浓度低于培养水平的输入性病例
Mengling Jiang,Muchun Wan,Qinghong Fan et al.
Mengling Jiang et al.
Chikungunya virus (CHIKV) infection, responsible for chikungunya fever and occasionally severe symptoms, has emerged as an increasing global health concern following several large-scale outbreaks from Africa, Asia, Europe, and America. Over...
Wenjing Liu,Erxin Zhang,Wei Li et al.
Wenjing Liu et al.
Mpox is a zoonotic disease caused by the monkeypox virus (MPXV). Diagnosing and treating the disease has become a global health concern requiring close attention to its spread to non-endemic regions. Clinical diagnosis is based on laborator...
Vaccinia virus Tiantan strain blocks host antiviral innate immunity and programmed cell death by disrupting gene expression [0.03%]
天坛株痘苗病毒通过干扰基因表达来阻断宿主抗病毒固有免疫和程序性细胞死亡
Changcheng Wu,Zhongxian Zhang,Zhaoqing Li et al.
Changcheng Wu et al.
The vaccinia virus Tiantan (VTT) is widely utilized as a smallpox vaccine in China and holds significant importance in the prevention of diseases stemming from poxvirus infections. Nevertheless, few studies have investigated the influence o...
Drupacine as a potent SARS-CoV-2 replication inhibitor in vitro [0.03%]
德鲁帕西恩作为强有力的SARS-CoV-2体外复制抑制剂
Chen Yang,Yanying Yu,Qi Peng et al.
Chen Yang et al.
Despite the availability of vaccines and antiviral treatments, the continued emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants and breakthrough infections underscores the need for new, potent antiviral thera...
An outbreak of rhinovirus infection in a primary school in Shenyang City, China, in 2022 [0.03%]
中国沈阳市某小学2022年发生的一起鼻病毒疫情爆发事件
Yage Wang,Jiayuan Liang,Zhibo Xie et al.
Yage Wang et al.
Rhinovirus (RV) is a common pathogen that causes respiratory tract infection and can cause outbreaks in hospitals and welfare institutions. A cluster of respiratory diseases occurred in a primary school in Shenyang City, Liaoning Province, ...
Developing an advanced course of vaccinology in middle-income countries: The case of China [0.03%]
在中等收入国家开展高级疫苗学课程的案例研究：中国的实例
Likui Wang,Lei Guo,Yunguo Liu et al.
Likui Wang et al.
•We provide the Chinese Vaccinology Course was the only national advanced vaccinology training course in China, in response to the global call to improve vaccine capacity and meet local needs.•To address the challenges for both the develo...
Biosafety and immunology: An interdisciplinary field for health priority [0.03%]
生物安全与免疫学：一个面向健康重点的交叉学科领域
Jun Liu,Gary Wong,Hui Li et al.
Jun Liu et al.
Biosafety hazards can trigger a host immune response after infection, invasion, or contact with the host. Whether infection with a microorganism results in disease or biosafety concerns depends to a large extent on the immune status of the ...
Construction of pseudotyped human coronaviruses and detection of pre-existing antibodies in the human population [0.03%]
伪型人类冠状病毒的构建及人群中既存抗体的检测
Qi Jiang,Xi Wu,Fangyu Dong et al.
Qi Jiang et al.
In order to clarify the pre-exist immunity background of different human coronaviruses (HCoV), this study investigated the positive rate of spike (S) protein antibodies of HCoV, including HCoV- severe acute respiratory syndrome (SARS) -asso...
Impact of ursodeoxycholic acid therapy in autoimmune liver disease patients with COVID-19 and its clinical prognosis [0.03%]
熊去氧胆酸疗法对患有COVID-19的自身免疫性肝病患者及其临床预后的影响
Minghui Li,Weihua Cao,Tingting Jiang et al.
Minghui Li et al.
To explore the impact of ursodeoxycholic acid (UDCA) on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and clinical outcomes in patients with autoimmune liver disease (AILD). Patients diagnosed with AILD were enrolle...
Evaluation of antibody responses in healthy individuals receiving SARS-CoV-2 inactivated vaccines [0.03%]
健康个体接受SARS-CoV-2灭活疫苗的抗体反应评价
Ziyu Liu,Liyan Cai,Man Xing et al.
Ziyu Liu et al.
Inactivated coronavirus disease 2019 (COVID-19) vaccines such as CoronaVac and BBIBP-CorV have been widely used in China. However, more investigation is still needed to understand antibodies' duration and effectiveness against severe acute ...