1,2,3, MHC: a review of mass-spectrometry-based immunopeptidomics methods for relative and absolute quantification of pMHCs [0.03%]
1,2,3,MHC：基于质谱的相对和绝对定量PMHC免疫肽组方法综述
L E Stopfer,A D D&#x;Souza,F M White
L E Stopfer
Quantitative mass-spectrometry-based methods to perform relative and absolute quantification of peptides in the immunopeptidome are growing in popularity as researchers aim to measure the dynamic nature of the peptide major histocompatibili...
[This corrects the article DOI: 10.1016/j.iotech.2019.11.003.][This corrects the article DOI: 10.1016/j.iotech.2021.100034.][This corrects the article DOI: 10.1016/j.iotech.2020.03.001.][This corrects the article DOI: 10.1016/j.iotech.2019....
Published Erratum
Immuno-oncology technology. 2021 Nov 12:11:100051. DOI:10.1016/j.iotech.2021.100051 2021
The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens [0.03%]
功能遗传筛查发现肿瘤固有的免疫敏感决定因素
D W Vredevoogd,G Apriamashvili,D S Peeper
D W Vredevoogd
Functional genetic screens by CRISPR-Cas9 allow for the unbiased discovery of proteins causally involved in complex biological processes. In recent years, this approach has been used by multiple laboratories to uncover a range of tumor cell...
Z Bodalal,I Wamelink,S Trebeschi et al.
Z Bodalal et al.
With the ongoing advances in imaging techniques, increasing volumes of anatomical and functional data are being generated as part of the routine clinical workflow. This surge of available imaging data coincides with increasing research in q...
S Peters,J Tabernero,A Cervantes et al.
S Peters et al.
Germline genetic host factors as predictive biomarkers in immuno-oncology [0.03%]
免疫肿瘤学中作为预测生物标志物的生殖系遗传宿主因素
Vylyny Chat,Robert Ferguson,Tomas Kirchhoff
Vylyny Chat
In immuno-oncology (IO), the baseline host factors attract significant clinical interest as promising predictive biomarker candidates. Growing evidence from experimental or population-based studies suggests that the host genetic factors con...
Qian Chen,Tianyuan Ci,Zhen Gu
Qian Chen
Background: Surgery remains the first option to treat most solid tumors. However, despite the development of surgical techniques, the elimination of tumor recurrence after surgery remains a challenge. ...
John B Haanen
John B Haanen
High multiplex analysis of the immune microenvironment in bone marrow trephine samples using GeoMX™ digital spatial profiling [0.03%]
采用GeoMX数字空间分析技术对骨髓活检样本免疫微环境进行高通量分析
R M Koldej,D S Ritchie
R M Koldej
Background: To date, studies into the bone marrow (BM) immune microenvironment have been limited due to reliance on the analysis of BM aspirates in which the microenvironmental context is lost. GeoMX™ digital spatial pro...
E A Lim,C G Drake,A Mintz
E A Lim
Immunotherapy has changed the treatment landscape for many cancers; however, not all patients treated have a favorable response and others can develop immune-related adverse events. A method to predict the treatment response to immunotherap...